Screening for HTLV-1 infection should be expanded in Europe
HTLV-1 infection is spreading globally at an uncertain speed [1, 2]. This is not surprising since viral transmission occurs following sexual, parenteral and vertical exposure, and HTLV testing is rare in most regions. Moreover, as only 10% of carriers develop serious clinical manifestations lifelong, the HTLV-1 pandemic largely runs silently involving people unaware of their infection [3]. Finally, to date there is neither protective vaccine nor antiviral therapy. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - January 31, 2024 Category: Infectious Diseases Authors: Vicente Soriano, Carmen de-Mendoza, Spanish HTLV Network Tags: Perspective Source Type: research

“MAMA’s is like a second mom:” Client and Staff Experiences in a Comprehensive Social Risk Care Management Program Within a Perinatal Medical Home
This study seeks to understand the experiences of staff and clients within the MAMA’s program to identify what factors decrease stress, how the program addresses racism and the challenges and opportunities of optimizing health during the COVID-19 pandemic.Methods21 staff and 34 clients completed semi-structured interviews from November 2020 –December 2021. Separate interview guides for staff and clients explored experiences within the program, experiences during the COVID-19 pandemic, and how racism affects clients. Interviews were recorded and transcribed. Analysis used a phenomenologic framework. Coding was performed...
Source: Maternal and Child Health Journal - January 31, 2024 Category: Health Management Source Type: research

Experiences of Spanish out-of-hospital emergency workers with high levels of depression during the COVID-19 pandemic: a qualitative study
ConclusionThe strong impact of the circumstances experienced points to the need to develop psychological support programmes that can protect people ’s mental health from depression during a crisis and improve the relationship between workers and their managers. (Source: Archives of Public Health)
Source: Archives of Public Health - January 30, 2024 Category: International Medicine & Public Health Source Type: research

Viruses, Vol. 16, Pages 201: Hypoxia and Activation of Neutrophil Degranulation-Related Genes in the Peripheral Blood of COVID-19 Patients
In this study, consensus gene dysregulation in the blood was obtained from 13 independent transcriptome studies on COVID-19. Among the up-regulated genes, the most prominent functional categories were neutrophil degranulation and cell cycle, which is clearly different from the classical activation of interferon signaling pathway in seasonal flu. As for the potential upstream causal factors of the atypical gene dysregulation, systemic hypoxia was further examined because it is much more widely reported in COVID-19 than that in seasonal flu. It was found that both physiological and pathological hypoxia can induce activation ...
Source: Viruses - January 28, 2024 Category: Virology Authors: Hongxing Lei Tags: Article Source Type: research

Spatial and social aspects of the 1918-1919 pandemic flu in split
Acta Med Hist Adriat. 2024 Jan 2;21(2):259-282. doi: 10.31952/amha.21.2.4.ABSTRACTThe Spanish flu pandemic is considered the largest and most dangerous epidemic at the beginning of the 20th century affecting most of the world today. The Spanish flu pandemic did not bypass the territory of Croatia (at the time, Croatia was part of the Austro-Hungarian Monarchy), nor its southern coastal region of Dalmatia and the city of Split. Using the example of the city Split, the paper analyses the spatial and demographic determinants of population mortality from the Spanish flu between 1918 and 1919, i.e., from March 1918 to April 191...
Source: Medical History - January 25, 2024 Category: History of Medicine Authors: Lena Miro šević Antonia Mi ć Source Type: research