Exploring the molecular mechanisms and shared gene signatures between celiac disease and ulcerative colitis based on bulk RNA and single-cell sequencing: Experimental verification

In conclusion, our study elucidated that abnormal immune response could be the common pathogenesis of UC and CeD, and REG4 might be a key potential biomarker and therapeutic target for the comorbidity of these two diseases.PMID:38615385 | DOI:10.1016/j.intimp.2024.112059

Source: International Immunopharmacology - April 14, 2024 Category: Allergy & Immunology Authors: Changshan Wan Tao Ji Liwei Wang Qiuyan Wu Qiuyu Chen Yali Wang Yaqian Li Fengming He Wentian Liu Weilong Zhong Bangmao Wang Source Type: research