The expression of trefoil factor family member 2 in increased at an acidic pH

In conclusion, TFF2 was highly expressed under acidic conditions, implying that it may have an important function in protecting the plasma membrane from acidic environments in both normal and cancer cells. These findings warrant further investigation of TFF2 as a target of cancer therapy and diagnosis.PMID:38572063 | PMC:PMC10988190 | DOI:10.3892/ol.2024.14345

Source: Oncology Letters - April 4, 2024 Category: Cancer & Oncology Authors: Yui Masumoto Suzuka Matsuo Natsuno Kinjou Yuka Narieda Morimasa Wada Kyoko Fujimoto Source Type: research