STUB1 increases adiponectin expression by inducing ubiquitination and degradation of NR2F2, thereby reducing hepatic stellate cell activation and alleviating non-alcoholic fatty liver disease

CONCLUSION: This study highlights the role of STUB1 in reducing HSC activation and alleviating NAFLD by attenuating NR2F2-mediated transcriptional repression of APN.PMID:38471267 | DOI:10.1016/j.tice.2024.102345

Source: Tissue and Cell - March 12, 2024 Category: Cytology Authors: Zheng Mao Jindong Zhao Fan Cui Zhen Li Jinjin Cao Jingjing Zhou Mingliang Hou Zengkun Qian Source Type: research