Severe pediatric COVID-19: a review from the clinical and immunopathophysiological perspectives

CONCLUSIONS: Severe pediatric COVID-19 can affect multiple organ systems. The dysregulated immune pathways in severe COVID-19 shape the disease course, epitomize the vast functional diversity of the pediatric immune system and highlight the immunophenotypical differences between children and adults. Consequently, further research may be warranted to adequately address them in pediatric-specific clinical practice guidelines.PMID:38321331 | DOI:10.1007/s12519-023-00790-y

Source: World Journal of Pediatrics : WJP - February 6, 2024 Category: Pediatrics Authors: Yi-Kan Sun Can Wang Pei-Quan Lin Lei Hu Jing Ye Zhi-Gang Gao Ru Lin Hao-Min Li Qiang Shu Li-Su Huang Lin-Hua Tan Source Type: research