Comparison of remimazolam and propofol combined with low dose esketamine for pediatric same-day painless bidirectional endoscopy: a randomized, controlled clinical trial

Conclusion: Remimazolam combined with low dose esketamine has a non-inferior sedative effect than propofol for pediatric BDE, with no injection pain, less respiratory depression, more stable hemodynamics. Moreover, early detection of the decline in PI may avoid harmful stimulation under light anesthesia.Clinical trial registration:https://www.clinicaltrials.gov/study/NCT05686863?id=NCT05686863&rank=1, NCT05686863
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research