Autonomic activity and cardiovascular system risk assessment in pediatric patients with hemolytic uremic syndrome

Conclusion: Patients with HUS may have autonomic nervous system dysfunction. HRV measurement is a non-invasive method that can evaluate this. It can be thought that there may be an increased risk of cardiovascular events and arrhythmias in some patients with HUS. ECG should be also considered to detect arrhythmia.What is Known:• Hemolytic uremic syndrome (HUS) primarily effects the hematologic parameters and kidney.• Secondary cardiomyopathy with hypertension and renal failure could be observed in these patients.• Rhythm problems are not expected primarily in these patients.• There is very limited data in evaluating autonomic function and arrhythmia risk for these patients.What is New:• Patients with HUS may have autonomic nervous system dysfunction.• HRV measurement is a non-invasive method that can evaluate this.• Cardiovascular events and arrhythmias due to the deterioration of the balance between the sympathetic and parasympathetic systems could manifest in patients with HUS.• An ECG and screening patients for cardiac events, and monitoring them closely should be considered.
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research