A comprehensive analysis of mRNA expression profiles of Esophageal Squamous Cell Carcinoma reveals downregulation of Desmoglein 1 and crucial genomic targets
CONCLUSION: We identified novel perturbed genes in relation to ESCC and explored their interaction network. DSG1 is one such gene, its association with microbiota and a clinical presentation seen commonly with ESCC hints that it is a good candidate for early diagnostic marker. Besides, in this study we highlight candidate genes and their molecular connections to risk factors, biological pathways, drug chemicals, and the survival probability of ESCC patients.PMID:38073377 | DOI:10.3233/CBM-230145
Source: Cancer Biomarkers : Section A of Disease Markers - Category: Cancer & Oncology Authors: Amal Alotaibi Veerendra P Gadekar Pranav Swaroop Gundla Sumana Mandarthi Subramanyeshwari Ravi Dhyeya Mallya Asna Tungekar B V Lavanya Ashok Kumar Bhagavath MaryAnne Wong Cordero Janne Pitkaniemi Raviraja N Seetharam Asmatanzeem Bepari Prashantha Hebbar Source Type: research
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