The effects of green tea extract supplementation on body composition, obesity-related hormones, and oxidative stress markers: A grade-assessed systematic review and dose-response meta-analysis of randomized controlled trials

Br J Nutr. 2023 Nov 30:1-77. doi: 10.1017/S000711452300260X. Online ahead of print.ABSTRACTResearch indicates that green tea extract (GTE) supplementation is beneficial for a range of conditions, including several forms of cancer, cardiovascular, and liver diseases; nevertheless, the existing evidence addressing its effects on body composition, oxidative stress, and obesity-related hormones is inconclusive. This systematic review and meta-analysis aimed to investigate the effects of GTE supplementation on body composition (body mass [BM], body fat percentage [BFP], fat mass [FM], body mass index [BMI], waist circumference [WC]), obesity-related hormones (leptin, adiponectin, and ghrelin) and oxidative stress (malondialdehyde [MDA], and total antioxidant capacity [TAC]) markers. We searched proper databases, including PubMed/Medline, Scopus, and Web of Science, up to July 2022 to recognize published randomized controlled trials (RCTs) that investigated the effects of GTE supplementation on the markers mentioned above. A random-effects model was used to carry out a meta-analysis. The heterogeneity among the studies was assessed using the I2 index. Among the initial 11286 studies identified from an electronic database search, 59 studies involving 3802 participants were eligible to be included in this meta-analysis. Pooled effect sizes indicated that BM, BFP, BMI, and MDA significantly reduced following GTE supplementation. In addition, GTE supplementation increased adiponectin a...
Source: The British Journal of Nutrition - Category: Nutrition Authors: Source Type: research