Direct and indirect effects of alcohol and its toxic metabolite acetaldehyde on human esophageal myofibroblasts and epithelial cells
CONCLUSIONS: Alcohol and acetaldehyde doses in which the majority of HEMFs and epithelial cells are healthy, elicit production of paracrine mediators with pro-proliferative effects on neighboring cells. Understanding the effect of alcohol and acetaldehyde on HEMFs and HEMF-epithelial interactions may help identify the molecular basis by which alcohol increases risk for esophageal cancer.PMID:37128647 | DOI:10.1111/acer.15093
Source: Alcoholism, Clinical and Experimental Research - Category: Addiction Authors: Atousa Khalatbari Joshua D Castle Tao Li Anisa Shaker Source Type: research
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