Heart failure in chronic kidney disease – Cardiology Basics

Heart failure in chronic kidney disease – Cardiology Basics Prevalence of both heart failure and chronic kidney disease (CKD) are increasing as the population is aging globally. Hence heart failure in chronic kidney disease is seen more often. Presence of CKD in heart failure increases morbidity and mortality. Though there is increasing use of effective medications and special devices like cardiac resynchronization therapy in heart failure patients in general, those with CKD have not been benefited well. CKD is defined as abnormalities of kidney structure or function, present for >3 months, with implications for health. A more detailed definition is persistently reduced estimated glomerular filtration rate (eGFR) of <60 ml/min per 1.73 sq. m. or at least 1 marker of kidney damage for >3 months. The markers of kidney damage include albuminuria, urine sediment abnormalities, histological, or structural abnormalities detected on imaging. History of renal transplantation is also included among markers of kidney damage. Significant albuminuria is albumin excretion rate of 30 mg/24 hours or more and albumin creatinine ratio of 30 mg/g or more. Heart failure can occur in those on dialysis as well as those who have kidney disease not requiring dialysis. Naturally those on dialysis have more advanced kidney disease. Major medications used in heart failure can also be used in those with heart failure and mild-moderate CKD. But caution is needed because angiotensin conver...
Source: Cardiophile MD - Category: Cardiology Authors: Tags: General Cardiology Source Type: blogs