Periodontal disease linked to heart failure – New study report

Periodontal disease linked to heart failure – New study report Periodontal disease is known to be associated with coronary artery disease as well as poses a risk for bacteremia and subsequent risks [1]. A recent report looked at 6707 participants of the ARIC (Atherosclerosis Risk In Communities) study who had full-mouth periodontal examination at visit 4 between 1996-1998 and longitudinal follow up for incident heart failure. Data on incident heart failure was checked from visit 4 to 2018. In addition data on incident heart failure with preserved ejection fraction (HFpEF) and heart failure with reduced ejection fraction (HFrEF) between 2005-2018 was also analyzed [2]. Periodontal status was classified as healthy, periodontal disease or edentulous as per the Periodontal Profile Classification. Association between these Periodontal Profile Classification levels and incident heart failure, HFpEF and HFrEF were calculated. Biomarker of inflammation C-reactive protein (CRP) and biomarker of congestion N-terminal brain natriuretic peptide (NT-proBNP) were assessed. Of the total 1,178 incident heart failure, 350 were HFpEF, 319 HFrEF and 509 of unknown type, over a median period of 13 years. 59% of these cases had periodontal disease while 18% were edentulous. Both periodontal disease and edentulism was thus associated with increased risk for all varieties of heart failure. In addition, edentulism was associated with unfavourable change in CRP and NT-proBNP while periodontal d...
Source: Cardiophile MD - Category: Cardiology Authors: Tags: General Cardiology Source Type: blogs