Label-Free Mass Spectrometry-Based Quantitative Proteomics to Evaluate the Effects of the Calcium-Sensing Receptor Agonist Cinacalcet on Protein Expression in Rat Brains and Livers

CONCLUSIONS These findings indicate that long-term cinacalcet therapy can impair phase II of enzymatic detoxication and can cause disturbances in blood hemostasis, lipid metabolism, and inflammatory mediators or contribute to the acceleration of cognitive dysfunction; therefore, appropriate patient monitoring should be considered.PMID:35941808 | DOI:10.12659/MSM.937338

Source: Medical Science Monitor - August 9, 2022 Category: Research Authors: Ewa Bulska Andrzej Gawor Anna Konopka Grzegorz Wryk Bo żena Czarkowska-Pączek Zdzis ław Gajewski Leszek P ączek Source Type: research