Accumulation of resistance genes in < em > Salmonella < /em > Typhimurium transmitted between poultry and dairy farms increases the risk to public health
Appl Environ Microbiol. 2024 May 9:e0229723. doi: 10.1128/aem.02297-23. Online ahead of print.ABSTRACTSalmonella Typhimurium is a zoonotic pathogen that poses a major threat to public health. This generalist serotype can be found in many hosts and the environment where varying selection pressures may result in the accumulation of antimicrobial resistance determinants. However, the transmission of this serotype between food-producing hosts, specifically between poultry layer flocks and nearby dairy herds, was never demonstrated. We investigated an outbreak at a dairy in Israel to determine the role of nearby poultry houses ...
Source: Applied and Environmental Microbiology - May 9, 2024 Category: Microbiology Authors: Janet Perry Katya Arnold Cinthia Satuchne Ori Koren Gaby Kenigswald Ehud Elnekave Source Type: research
Seroprevalence of Toxoplasma gondii, risk factors and knowledge about toxoplasmosis in undergraduate students from Lima, Peru
Acta Trop. 2024 May 7:107233. doi: 10.1016/j.actatropica.2024.107233. Online ahead of print.ABSTRACTToxoplasma gondii is the causative agent of toxoplasmosis, a zoonotic disease of worldwide distribution. The aim of this study was to assess the seroprevalence of T. gondii in undergraduate students from Lima, Peru, and to identify the risk factors linked to the infection. For this, serum samples of 100 undergraduate students of the Faculty of Biological Sciences were tested for T. gondii antibodies with a commercially available ELISA. The seroprevalence of T. gondii in these subjects was 7%. Only the age of students showed ...
Source: Acta Tropica - May 9, 2024 Category: Infectious Diseases Authors: Juan Jimenez-Chunga Luis A Gomez-Puerta Ana Vargas-Calla Julia Castro-Hidalgo Carol S ánchez-Chicana Maritza Calder ón-Sánchez Source Type: research
Accumulation of resistance genes in < em > Salmonella < /em > Typhimurium transmitted between poultry and dairy farms increases the risk to public health
Appl Environ Microbiol. 2024 May 9:e0229723. doi: 10.1128/aem.02297-23. Online ahead of print.ABSTRACTSalmonella Typhimurium is a zoonotic pathogen that poses a major threat to public health. This generalist serotype can be found in many hosts and the environment where varying selection pressures may result in the accumulation of antimicrobial resistance determinants. However, the transmission of this serotype between food-producing hosts, specifically between poultry layer flocks and nearby dairy herds, was never demonstrated. We investigated an outbreak at a dairy in Israel to determine the role of nearby poultry houses ...
Source: Applied and Environmental Microbiology - May 9, 2024 Category: Microbiology Authors: Janet Perry Katya Arnold Cinthia Satuchne Ori Koren Gaby Kenigswald Ehud Elnekave Source Type: research
Seroprevalence of Toxoplasma gondii, risk factors and knowledge about toxoplasmosis in undergraduate students from Lima, Peru
Acta Trop. 2024 May 7:107233. doi: 10.1016/j.actatropica.2024.107233. Online ahead of print.ABSTRACTToxoplasma gondii is the causative agent of toxoplasmosis, a zoonotic disease of worldwide distribution. The aim of this study was to assess the seroprevalence of T. gondii in undergraduate students from Lima, Peru, and to identify the risk factors linked to the infection. For this, serum samples of 100 undergraduate students of the Faculty of Biological Sciences were tested for T. gondii antibodies with a commercially available ELISA. The seroprevalence of T. gondii in these subjects was 7%. Only the age of students showed ...
Source: Acta Tropica - May 9, 2024 Category: Infectious Diseases Authors: Juan Jimenez-Chunga Luis A Gomez-Puerta Ana Vargas-Calla Julia Castro-Hidalgo Carol S ánchez-Chicana Maritza Calder ón-Sánchez Source Type: research
Leptospirosis in a patient with cardiac manifestation: A case report study and literature review
We describe a 37-year-old male farmer who initially sought medical attention for general symptoms that had been deteriorating despite receiving outpatient treatment for 3 days for a presumed diagnosis of influenza. During his initial assessment, he exhibited sinus bradycardia, anemia, leukocytosis, elevated levels of direct and total bilirubin, and abnormal liver function test results. Through thorough history-taking, physical examination, and laboratory analyses, a diagnosis of leptospirosis was conclusively established for him. Focusing on the patient's medical history, clinical manifestations, and thorough physical a...
Source: Clinical Case Reports - May 9, 2024 Category: General Medicine Authors: Narges Lashkarbolouk,
Mahdi Mazandarani Tags: CASE REPORT Source Type: research
Proteomic change in the upper lobe of the left lung of Beagle dogs at the lung migration stage of Toxocara canis infection
Toxocara canis is considered one of the most neglected parasitic zoonoses and threatens the health of millions of people worldwide with a predilection for pediatric and adolescent populations in impoverished comm... (Source: Parasites and Vectors)
Source: Parasites and Vectors - May 9, 2024 Category: Microbiology Authors: Wen-Bin Zheng, Hui-Jie Qiu, Han-Dan Xiao, Yang Zou and Xing-Quan Zhu Tags: Research Source Type: research
Brucellar arthritis and sacroiliitis: an 8-year retrospective comparative analysis of demographic, clinical, and paraclinical features
CONCLUSION: Arthritis and sacroiliitis were the two most important and common manifestations of brucellar osteoarthritis with a frequency of 9.64% and 13.6%, respectively. Any complaints of low back pain and radiculopathy as well as the presence of spondylitis in patients should raise suspicion of sacroiliitis. High levels of AST and ALP and a high platelet count may be associated with brucellar sacroiliitis and arthritis, respectively. The use of imaging methods such as MRI and bone scan seems necessary for the diagnosis of sacroiliitis.PMID:38716079 | PMC:PMC11075600 | DOI:10.1177/20499361241246937 (Source: Adv Data)
Source: Adv Data - May 8, 2024 Category: Epidemiology Authors: Sanaz Morovati Arezoo Bozorgomid Arman Mohammadi Forouzan Ahmadi Leila Arghand Fatemeh Khosravi Shadmani Babak Sayad Source Type: research
Evaluation of LN34 Pan-Lyssavirus RT-qPCR assay for rabies diagnosis in Brazil
This study evaluated its performance using 130 rabies virus isolates representing eleven Brazilian variants and 303 clinical samples from surveillance operations. The LN34 assay demonstrated 100% sensitivity and 98% specificity compared to dFAT. Additionally, it detected all samples, including those missed by dFAT, indicating superior sensitivity. The assay's specificity was confirmed through Sanger nucleotide sequencing, with only a minimal false-positive rate. Comparative analysis revealed higher accuracy and concordance with dFAT than traditional rabies tissue culture infection tests (RTCIT). False-negative RTCIT result...
Source: Journal of Virological Methods - May 8, 2024 Category: Virology Authors: M E R Chierato V B V Silveira D F P Pavani W O Fahl K Iamamoto K M Asano H B C R Batista K C Scheffer P C Maiorka E Mori Source Type: research
Leptospiral LipL45 lipoprotein undergoes processing and shares structural similarities with bacterial sigma regulators
Biochem Biophys Res Commun. 2024 May 4;717:150057. doi: 10.1016/j.bbrc.2024.150057. Online ahead of print.ABSTRACTLeptospirosis is a widespread zoonotic infectious disease of human and veterinary concern caused by pathogenic spirochetes of the genus Leptospira. To date, little progress towards understanding leptospiral pathogenesis and identification of virulence factors has been made, which is the main bottleneck for developing effective measures against the disease. Some leptospiral proteins, including LipL32, Lig proteins, LipL45, and LipL21, are being considered as potential virulence factors or vaccine candidates. How...
Source: Cell Research - May 8, 2024 Category: Cytology Authors: Gabriel de Assis Noman B árbara Emmanuelle Lacerda de Moura M ônica Larucci Vieira Source Type: research
Brucellar arthritis and sacroiliitis: an 8-year retrospective comparative analysis of demographic, clinical, and paraclinical features
CONCLUSION: Arthritis and sacroiliitis were the two most important and common manifestations of brucellar osteoarthritis with a frequency of 9.64% and 13.6%, respectively. Any complaints of low back pain and radiculopathy as well as the presence of spondylitis in patients should raise suspicion of sacroiliitis. High levels of AST and ALP and a high platelet count may be associated with brucellar sacroiliitis and arthritis, respectively. The use of imaging methods such as MRI and bone scan seems necessary for the diagnosis of sacroiliitis.PMID:38716079 | PMC:PMC11075600 | DOI:10.1177/20499361241246937 (Source: Adv Data)
Source: Adv Data - May 8, 2024 Category: Epidemiology Authors: Sanaz Morovati Arezoo Bozorgomid Arman Mohammadi Forouzan Ahmadi Leila Arghand Fatemeh Khosravi Shadmani Babak Sayad Source Type: research
Leptospiral LipL45 lipoprotein undergoes processing and shares structural similarities with bacterial sigma regulators
Biochem Biophys Res Commun. 2024 May 4;717:150057. doi: 10.1016/j.bbrc.2024.150057. Online ahead of print.ABSTRACTLeptospirosis is a widespread zoonotic infectious disease of human and veterinary concern caused by pathogenic spirochetes of the genus Leptospira. To date, little progress towards understanding leptospiral pathogenesis and identification of virulence factors has been made, which is the main bottleneck for developing effective measures against the disease. Some leptospiral proteins, including LipL32, Lig proteins, LipL45, and LipL21, are being considered as potential virulence factors or vaccine candidates. How...
Source: Biochemical and Biophysical Research communications - May 8, 2024 Category: Biochemistry Authors: Gabriel de Assis Noman B árbara Emmanuelle Lacerda de Moura M ônica Larucci Vieira Source Type: research
Evaluation of LN34 Pan-Lyssavirus RT-qPCR assay for rabies diagnosis in Brazil
This study evaluated its performance using 130 rabies virus isolates representing eleven Brazilian variants and 303 clinical samples from surveillance operations. The LN34 assay demonstrated 100% sensitivity and 98% specificity compared to dFAT. Additionally, it detected all samples, including those missed by dFAT, indicating superior sensitivity. The assay's specificity was confirmed through Sanger nucleotide sequencing, with only a minimal false-positive rate. Comparative analysis revealed higher accuracy and concordance with dFAT than traditional rabies tissue culture infection tests (RTCIT). False-negative RTCIT result...
Source: Journal of Virological Methods - May 8, 2024 Category: Virology Authors: M E R Chierato V B V Silveira D F P Pavani W O Fahl K Iamamoto K M Asano H B C R Batista K C Scheffer P C Maiorka E Mori Source Type: research
Evaluation of LN34 Pan-Lyssavirus RT-qPCR assay for rabies diagnosis in Brazil
This study evaluated its performance using 130 rabies virus isolates representing eleven Brazilian variants and 303 clinical samples from surveillance operations. The LN34 assay demonstrated 100% sensitivity and 98% specificity compared to dFAT. Additionally, it detected all samples, including those missed by dFAT, indicating superior sensitivity. The assay's specificity was confirmed through Sanger nucleotide sequencing, with only a minimal false-positive rate. Comparative analysis revealed higher accuracy and concordance with dFAT than traditional rabies tissue culture infection tests (RTCIT). False-negative RTCIT result...
Source: Journal of Virological Methods - May 8, 2024 Category: Virology Authors: M E R Chierato V B V Silveira D F P Pavani W O Fahl K Iamamoto K M Asano H B C R Batista K C Scheffer P C Maiorka E Mori Source Type: research
Evaluation of LN34 Pan-Lyssavirus RT-qPCR assay for rabies diagnosis in Brazil
This study evaluated its performance using 130 rabies virus isolates representing eleven Brazilian variants and 303 clinical samples from surveillance operations. The LN34 assay demonstrated 100% sensitivity and 98% specificity compared to dFAT. Additionally, it detected all samples, including those missed by dFAT, indicating superior sensitivity. The assay's specificity was confirmed through Sanger nucleotide sequencing, with only a minimal false-positive rate. Comparative analysis revealed higher accuracy and concordance with dFAT than traditional rabies tissue culture infection tests (RTCIT). False-negative RTCIT result...
Source: Journal of Virological Methods - May 8, 2024 Category: Virology Authors: M E R Chierato V B V Silveira D F P Pavani W O Fahl K Iamamoto K M Asano H B C R Batista K C Scheffer P C Maiorka E Mori Source Type: research
