Interactive neuroinflammation pathways and transcriptomics-based identification of drugs and chemical compounds for schizophrenia
Conclusions: New neuroinflammatory pathways incorporating the extracellular matrix, glutamatergic neurons, and astrocytes in the aetiology of schizophrenia were established. Transcriptomics based network analysis provided novel targets, including extra-synaptic glutamate receptors, glutamate transporters and extracellular matrix molecules that can be evaluated for therapeutic strategies.PMID:37961844 | DOI:10.1080/15622975.2023.2281514 (Source: The World Journal of Biological Psychiatry)
Source: The World Journal of Biological Psychiatry - November 14, 2023 Category: Psychiatry Authors: Lisa Koole Pilar Martinez-Martinez Therese van Amelsvoort Chris T Evelo Friederike Ehrhart Source Type: research
Interactive neuroinflammation pathways and transcriptomics-based identification of drugs and chemical compounds for schizophrenia
Conclusions: New neuroinflammatory pathways incorporating the extracellular matrix, glutamatergic neurons, and astrocytes in the aetiology of schizophrenia were established. Transcriptomics based network analysis provided novel targets, including extra-synaptic glutamate receptors, glutamate transporters and extracellular matrix molecules that can be evaluated for therapeutic strategies.PMID:37961844 | DOI:10.1080/15622975.2023.2281514 (Source: The World Journal of Biological Psychiatry)
Source: The World Journal of Biological Psychiatry - November 14, 2023 Category: Psychiatry Authors: Lisa Koole Pilar Martinez-Martinez Therese van Amelsvoort Chris T Evelo Friederike Ehrhart Source Type: research
Interactive neuroinflammation pathways and transcriptomics-based identification of drugs and chemical compounds for schizophrenia
Conclusions: New neuroinflammatory pathways incorporating the extracellular matrix, glutamatergic neurons, and astrocytes in the aetiology of schizophrenia were established. Transcriptomics based network analysis provided novel targets, including extra-synaptic glutamate receptors, glutamate transporters and extracellular matrix molecules that can be evaluated for therapeutic strategies.PMID:37961844 | DOI:10.1080/15622975.2023.2281514 (Source: The World Journal of Biological Psychiatry)
Source: The World Journal of Biological Psychiatry - November 14, 2023 Category: Psychiatry Authors: Lisa Koole Pilar Martinez-Martinez Therese van Amelsvoort Chris T Evelo Friederike Ehrhart Source Type: research
Interactive neuroinflammation pathways and transcriptomics-based identification of drugs and chemical compounds for schizophrenia
Conclusions: New neuroinflammatory pathways incorporating the extracellular matrix, glutamatergic neurons, and astrocytes in the aetiology of schizophrenia were established. Transcriptomics based network analysis provided novel targets, including extra-synaptic glutamate receptors, glutamate transporters and extracellular matrix molecules that can be evaluated for therapeutic strategies.PMID:37961844 | DOI:10.1080/15622975.2023.2281514 (Source: The World Journal of Biological Psychiatry)
Source: The World Journal of Biological Psychiatry - November 14, 2023 Category: Psychiatry Authors: Lisa Koole Pilar Martinez-Martinez Therese van Amelsvoort Chris T Evelo Friederike Ehrhart Source Type: research
Metabolites of Kimchi Lactic Acid Bacteria, Indole-3-Lactic Acid, Phenyllactic Acid, and Leucic Acid, Inhibit Obesity-Related Inflammation in Human Mesenchymal Stem Cells
J Microbiol Biotechnol. 2023 Oct 31;34(3):1-8. doi: 10.4014/jmb.2308.08015. Online ahead of print.ABSTRACTGiven the diversity of vegetables utilized in food fermentation and various lactic acid bacteria (LAB) populations in these materials, comprehensive studies on LAB from vegetable foods, including kimchi, are imperative. Therefore, this study aimed to investigate the obesity-related inflammation response of three metabolites-phenyllactic acid (PLA), indole-3-lactic acid (ILA), and leucic acid (LA)-produced by LAB (Companilactobacillus allii WiKim39 and Lactococcus lactis WiKim0124) isolated from kimchi. Their effects on...
Source: Journal of Microbiology and Biotechnology - November 8, 2023 Category: Biotechnology Authors: Moeun Lee Daun Kim Ji Yoon Chang Source Type: research
Proximity of alcohol outlets and presentation to hospital by young people after self-harm: A retrospective geospatial study using the integrated data infrastructure
CONCLUSIONS: The findings of this study show a clear association between young people's access to alcohol outlets and presentation to hospital for self-harm and may provide a mandate for government policies and universal interventions to reduce young people's access to alcohol outlets. Further research regarding causative mechanisms is needed.PMID:37888830 | DOI:10.1177/00048674231203909 (Source: The Australian and New Zealand Journal of Psychiatry)
Source: The Australian and New Zealand Journal of Psychiatry - October 27, 2023 Category: Psychiatry Authors: Sarah E Hetrick Matthew Hobbs Sarah Fortune Lukas Marek Jesse Wiki Joseph M Boden Reremoana Theodore Troy Ruhe Jesse J Kokaua Hiran Thabrew Barry Milne Nicholas Bowden Source Type: research
Proximity of alcohol outlets and presentation to hospital by young people after self-harm: A retrospective geospatial study using the integrated data infrastructure
CONCLUSIONS: The findings of this study show a clear association between young people's access to alcohol outlets and presentation to hospital for self-harm and may provide a mandate for government policies and universal interventions to reduce young people's access to alcohol outlets. Further research regarding causative mechanisms is needed.PMID:37888830 | DOI:10.1177/00048674231203909 (Source: The Australian and New Zealand Journal of Psychiatry)
Source: The Australian and New Zealand Journal of Psychiatry - October 27, 2023 Category: Psychiatry Authors: Sarah E Hetrick Matthew Hobbs Sarah Fortune Lukas Marek Jesse Wiki Joseph M Boden Reremoana Theodore Troy Ruhe Jesse J Kokaua Hiran Thabrew Barry Milne Nicholas Bowden Source Type: research
Proximity of alcohol outlets and presentation to hospital by young people after self-harm: A retrospective geospatial study using the integrated data infrastructure
CONCLUSIONS: The findings of this study show a clear association between young people's access to alcohol outlets and presentation to hospital for self-harm and may provide a mandate for government policies and universal interventions to reduce young people's access to alcohol outlets. Further research regarding causative mechanisms is needed.PMID:37888830 | DOI:10.1177/00048674231203909 (Source: The Australian and New Zealand Journal of Psychiatry)
Source: The Australian and New Zealand Journal of Psychiatry - October 27, 2023 Category: Psychiatry Authors: Sarah E Hetrick Matthew Hobbs Sarah Fortune Lukas Marek Jesse Wiki Joseph M Boden Reremoana Theodore Troy Ruhe Jesse J Kokaua Hiran Thabrew Barry Milne Nicholas Bowden Source Type: research
Proximity of alcohol outlets and presentation to hospital by young people after self-harm: A retrospective geospatial study using the integrated data infrastructure
CONCLUSIONS: The findings of this study show a clear association between young people's access to alcohol outlets and presentation to hospital for self-harm and may provide a mandate for government policies and universal interventions to reduce young people's access to alcohol outlets. Further research regarding causative mechanisms is needed.PMID:37888830 | DOI:10.1177/00048674231203909 (Source: The Australian and New Zealand Journal of Psychiatry)
Source: The Australian and New Zealand Journal of Psychiatry - October 27, 2023 Category: Psychiatry Authors: Sarah E Hetrick Matthew Hobbs Sarah Fortune Lukas Marek Jesse Wiki Joseph M Boden Reremoana Theodore Troy Ruhe Jesse J Kokaua Hiran Thabrew Barry Milne Nicholas Bowden Source Type: research
Proximity of alcohol outlets and presentation to hospital by young people after self-harm: A retrospective geospatial study using the integrated data infrastructure
CONCLUSIONS: The findings of this study show a clear association between young people's access to alcohol outlets and presentation to hospital for self-harm and may provide a mandate for government policies and universal interventions to reduce young people's access to alcohol outlets. Further research regarding causative mechanisms is needed.PMID:37888830 | DOI:10.1177/00048674231203909 (Source: The Australian and New Zealand Journal of Psychiatry)
Source: The Australian and New Zealand Journal of Psychiatry - October 27, 2023 Category: Psychiatry Authors: Sarah E Hetrick Matthew Hobbs Sarah Fortune Lukas Marek Jesse Wiki Joseph M Boden Reremoana Theodore Troy Ruhe Jesse J Kokaua Hiran Thabrew Barry Milne Nicholas Bowden Source Type: research
Proximity of alcohol outlets and presentation to hospital by young people after self-harm: A retrospective geospatial study using the integrated data infrastructure
CONCLUSIONS: The findings of this study show a clear association between young people's access to alcohol outlets and presentation to hospital for self-harm and may provide a mandate for government policies and universal interventions to reduce young people's access to alcohol outlets. Further research regarding causative mechanisms is needed.PMID:37888830 | DOI:10.1177/00048674231203909 (Source: The Australian and New Zealand Journal of Psychiatry)
Source: The Australian and New Zealand Journal of Psychiatry - October 27, 2023 Category: Psychiatry Authors: Sarah E Hetrick Matthew Hobbs Sarah Fortune Lukas Marek Jesse Wiki Joseph M Boden Reremoana Theodore Troy Ruhe Jesse J Kokaua Hiran Thabrew Barry Milne Nicholas Bowden Source Type: research
Proximity of alcohol outlets and presentation to hospital by young people after self-harm: A retrospective geospatial study using the integrated data infrastructure
CONCLUSIONS: The findings of this study show a clear association between young people's access to alcohol outlets and presentation to hospital for self-harm and may provide a mandate for government policies and universal interventions to reduce young people's access to alcohol outlets. Further research regarding causative mechanisms is needed.PMID:37888830 | DOI:10.1177/00048674231203909 (Source: The Australian and New Zealand Journal of Psychiatry)
Source: The Australian and New Zealand Journal of Psychiatry - October 27, 2023 Category: Psychiatry Authors: Sarah E Hetrick Matthew Hobbs Sarah Fortune Lukas Marek Jesse Wiki Joseph M Boden Reremoana Theodore Troy Ruhe Jesse J Kokaua Hiran Thabrew Barry Milne Nicholas Bowden Source Type: research
Proximity of alcohol outlets and presentation to hospital by young people after self-harm: A retrospective geospatial study using the integrated data infrastructure
CONCLUSIONS: The findings of this study show a clear association between young people's access to alcohol outlets and presentation to hospital for self-harm and may provide a mandate for government policies and universal interventions to reduce young people's access to alcohol outlets. Further research regarding causative mechanisms is needed.PMID:37888830 | DOI:10.1177/00048674231203909 (Source: The Australian and New Zealand Journal of Psychiatry)
Source: The Australian and New Zealand Journal of Psychiatry - October 27, 2023 Category: Psychiatry Authors: Sarah E Hetrick Matthew Hobbs Sarah Fortune Lukas Marek Jesse Wiki Joseph M Boden Reremoana Theodore Troy Ruhe Jesse J Kokaua Hiran Thabrew Barry Milne Nicholas Bowden Source Type: research
RNA expression in cord blood. Can obstructive sleep apnea (OSA) during pregnancy have any effect on fetal development?
Conclusions. Significant differences in gene expression profile in cord blood was found between samples from pregnancies with OSA and non-OSA that could potentially have a negative influence on various biological processes during fetal development (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Canaves, L., Gimenez, P., Fleischer, A., Muncunill, J., Cerda Moncades, M., Alvarez Ruiz De Larrinaga, A., Sanchez Baron, A., Codina Marcet, M., De La Pena Bravo, M., Barcelo Bennasar, A., Morell-Garcia, D., Pierola Lopetegui, J., Pena Zarza, J. A., Pinas Tags: Sleep science Source Type: research
How shrinking corn could help farmers —and the environment
Related podcast
Making corn shorter, and a book on finding India’s women in science
BY
Sarah Crespi
,
Angela Saini
,
Erik Stokstad
On 10 August 2020, a record-breaking windstorm raced across Iowa, the big buckle of the U.S. Corn Belt. Gusts up to 225 kilometers per hour flattened fields and buildings, with losses totaling an estimated $12 billion across several states. “It was devastating,” says Kelly Gillespie, a crop physiologist...
Source: Science of Aging Knowledge Environment - October 26, 2023 Category: Geriatrics Source Type: research
