Copy number variant risk loci for schizophrenia converge on the BDNF pathway
Conclusions: Our findings suggest that specific pathways - BDNF signaling - are critical contributors to schizophrenia risk conferred by rare CNVs. Our approach highlights the importance of not only investigating deleted or duplicated genes within pathogenic CNV loci, but also study their direct interaction partners, which may explain pleiotropic effects of CNVs on schizophrenia risk and offer a broader field for interventions.PMID:38493363 | DOI:10.1080/15622975.2024.2327027 (Source: The World Journal of Biological Psychiatry)
Source: The World Journal of Biological Psychiatry - March 17, 2024 Category: Psychiatry Authors: Friederike Ehrhart Ana Silva Therese van Amelsvoort Emma vonScheibler Chris Evelo David E J Linden Source Type: research
Copy number variant risk loci for schizophrenia converge on the BDNF pathway
Conclusions: Our findings suggest that specific pathways - BDNF signaling - are critical contributors to schizophrenia risk conferred by rare CNVs. Our approach highlights the importance of not only investigating deleted or duplicated genes within pathogenic CNV loci, but also study their direct interaction partners, which may explain pleiotropic effects of CNVs on schizophrenia risk and offer a broader field for interventions.PMID:38493363 | DOI:10.1080/15622975.2024.2327027 (Source: The World Journal of Biological Psychiatry)
Source: The World Journal of Biological Psychiatry - March 17, 2024 Category: Psychiatry Authors: Friederike Ehrhart Ana Silva Therese van Amelsvoort Emma vonScheibler Chris Evelo David E J Linden Source Type: research
Copy number variant risk loci for schizophrenia converge on the BDNF pathway
Conclusions: Our findings suggest that specific pathways - BDNF signaling - are critical contributors to schizophrenia risk conferred by rare CNVs. Our approach highlights the importance of not only investigating deleted or duplicated genes within pathogenic CNV loci, but also study their direct interaction partners, which may explain pleiotropic effects of CNVs on schizophrenia risk and offer a broader field for interventions.PMID:38493363 | DOI:10.1080/15622975.2024.2327027 (Source: The World Journal of Biological Psychiatry)
Source: The World Journal of Biological Psychiatry - March 17, 2024 Category: Psychiatry Authors: Friederike Ehrhart Ana Silva Therese van Amelsvoort Emma vonScheibler Chris Evelo David E J Linden Source Type: research
Copy number variant risk loci for schizophrenia converge on the BDNF pathway
Conclusions: Our findings suggest that specific pathways - BDNF signaling - are critical contributors to schizophrenia risk conferred by rare CNVs. Our approach highlights the importance of not only investigating deleted or duplicated genes within pathogenic CNV loci, but also study their direct interaction partners, which may explain pleiotropic effects of CNVs on schizophrenia risk and offer a broader field for interventions.PMID:38493363 | DOI:10.1080/15622975.2024.2327027 (Source: The World Journal of Biological Psychiatry)
Source: The World Journal of Biological Psychiatry - March 17, 2024 Category: Psychiatry Authors: Friederike Ehrhart Ana Silva Therese van Amelsvoort Emma vonScheibler Chris Evelo David E J Linden Source Type: research
Copy number variant risk loci for schizophrenia converge on the BDNF pathway
Conclusions: Our findings suggest that specific pathways - BDNF signaling - are critical contributors to schizophrenia risk conferred by rare CNVs. Our approach highlights the importance of not only investigating deleted or duplicated genes within pathogenic CNV loci, but also study their direct interaction partners, which may explain pleiotropic effects of CNVs on schizophrenia risk and offer a broader field for interventions.PMID:38493363 | DOI:10.1080/15622975.2024.2327027 (Source: The World Journal of Biological Psychiatry)
Source: The World Journal of Biological Psychiatry - March 17, 2024 Category: Psychiatry Authors: Friederike Ehrhart Ana Silva Therese van Amelsvoort Emma vonScheibler Chris Evelo David E J Linden Source Type: research
Copy number variant risk loci for schizophrenia converge on the BDNF pathway
Conclusions: Our findings suggest that specific pathways - BDNF signaling - are critical contributors to schizophrenia risk conferred by rare CNVs. Our approach highlights the importance of not only investigating deleted or duplicated genes within pathogenic CNV loci, but also study their direct interaction partners, which may explain pleiotropic effects of CNVs on schizophrenia risk and offer a broader field for interventions.PMID:38493363 | DOI:10.1080/15622975.2024.2327027 (Source: The World Journal of Biological Psychiatry)
Source: The World Journal of Biological Psychiatry - March 17, 2024 Category: Psychiatry Authors: Friederike Ehrhart Ana Silva Therese van Amelsvoort Emma vonScheibler Chris Evelo David E J Linden Source Type: research
Copy number variant risk loci for schizophrenia converge on the BDNF pathway
Conclusions: Our findings suggest that specific pathways - BDNF signaling - are critical contributors to schizophrenia risk conferred by rare CNVs. Our approach highlights the importance of not only investigating deleted or duplicated genes within pathogenic CNV loci, but also study their direct interaction partners, which may explain pleiotropic effects of CNVs on schizophrenia risk and offer a broader field for interventions.PMID:38493363 | DOI:10.1080/15622975.2024.2327027 (Source: The World Journal of Biological Psychiatry)
Source: The World Journal of Biological Psychiatry - March 17, 2024 Category: Psychiatry Authors: Friederike Ehrhart Ana Silva Therese van Amelsvoort Emma vonScheibler Chris Evelo David E J Linden Source Type: research
Copy number variant risk loci for schizophrenia converge on the BDNF pathway
Conclusions: Our findings suggest that specific pathways - BDNF signaling - are critical contributors to schizophrenia risk conferred by rare CNVs. Our approach highlights the importance of not only investigating deleted or duplicated genes within pathogenic CNV loci, but also study their direct interaction partners, which may explain pleiotropic effects of CNVs on schizophrenia risk and offer a broader field for interventions.PMID:38493363 | DOI:10.1080/15622975.2024.2327027 (Source: The World Journal of Biological Psychiatry)
Source: The World Journal of Biological Psychiatry - March 17, 2024 Category: Psychiatry Authors: Friederike Ehrhart Ana Silva Therese van Amelsvoort Emma vonScheibler Chris Evelo David E J Linden Source Type: research
Copy number variant risk loci for schizophrenia converge on the BDNF pathway
Conclusions: Our findings suggest that specific pathways - BDNF signaling - are critical contributors to schizophrenia risk conferred by rare CNVs. Our approach highlights the importance of not only investigating deleted or duplicated genes within pathogenic CNV loci, but also study their direct interaction partners, which may explain pleiotropic effects of CNVs on schizophrenia risk and offer a broader field for interventions.PMID:38493363 | DOI:10.1080/15622975.2024.2327027 (Source: The World Journal of Biological Psychiatry)
Source: The World Journal of Biological Psychiatry - March 17, 2024 Category: Psychiatry Authors: Friederike Ehrhart Ana Silva Therese van Amelsvoort Emma vonScheibler Chris Evelo David E J Linden Source Type: research
Copy number variant risk loci for schizophrenia converge on the BDNF pathway
Conclusions: Our findings suggest that specific pathways - BDNF signaling - are critical contributors to schizophrenia risk conferred by rare CNVs. Our approach highlights the importance of not only investigating deleted or duplicated genes within pathogenic CNV loci, but also study their direct interaction partners, which may explain pleiotropic effects of CNVs on schizophrenia risk and offer a broader field for interventions.PMID:38493363 | DOI:10.1080/15622975.2024.2327027 (Source: The World Journal of Biological Psychiatry)
Source: The World Journal of Biological Psychiatry - March 17, 2024 Category: Psychiatry Authors: Friederike Ehrhart Ana Silva Therese van Amelsvoort Emma vonScheibler Chris Evelo David E J Linden Source Type: research
Copy number variant risk loci for schizophrenia converge on the BDNF pathway
Conclusions: Our findings suggest that specific pathways - BDNF signaling - are critical contributors to schizophrenia risk conferred by rare CNVs. Our approach highlights the importance of not only investigating deleted or duplicated genes within pathogenic CNV loci, but also study their direct interaction partners, which may explain pleiotropic effects of CNVs on schizophrenia risk and offer a broader field for interventions.PMID:38493363 | DOI:10.1080/15622975.2024.2327027 (Source: The World Journal of Biological Psychiatry)
Source: The World Journal of Biological Psychiatry - March 17, 2024 Category: Psychiatry Authors: Friederike Ehrhart Ana Silva Therese van Amelsvoort Emma vonScheibler Chris Evelo David E J Linden Source Type: research
Copy number variant risk loci for schizophrenia converge on the BDNF pathway
Conclusions: Our findings suggest that specific pathways - BDNF signaling - are critical contributors to schizophrenia risk conferred by rare CNVs. Our approach highlights the importance of not only investigating deleted or duplicated genes within pathogenic CNV loci, but also study their direct interaction partners, which may explain pleiotropic effects of CNVs on schizophrenia risk and offer a broader field for interventions.PMID:38493363 | DOI:10.1080/15622975.2024.2327027 (Source: The World Journal of Biological Psychiatry)
Source: The World Journal of Biological Psychiatry - March 17, 2024 Category: Psychiatry Authors: Friederike Ehrhart Ana Silva Therese van Amelsvoort Emma vonScheibler Chris Evelo David E J Linden Source Type: research
Copy number variant risk loci for schizophrenia converge on the BDNF pathway
Conclusions: Our findings suggest that specific pathways - BDNF signaling - are critical contributors to schizophrenia risk conferred by rare CNVs. Our approach highlights the importance of not only investigating deleted or duplicated genes within pathogenic CNV loci, but also study their direct interaction partners, which may explain pleiotropic effects of CNVs on schizophrenia risk and offer a broader field for interventions.PMID:38493363 | DOI:10.1080/15622975.2024.2327027 (Source: The World Journal of Biological Psychiatry)
Source: The World Journal of Biological Psychiatry - March 17, 2024 Category: Psychiatry Authors: Friederike Ehrhart Ana Silva Therese van Amelsvoort Emma vonScheibler Chris Evelo David E J Linden Source Type: research
Copy number variant risk loci for schizophrenia converge on the BDNF pathway
Conclusions: Our findings suggest that specific pathways - BDNF signaling - are critical contributors to schizophrenia risk conferred by rare CNVs. Our approach highlights the importance of not only investigating deleted or duplicated genes within pathogenic CNV loci, but also study their direct interaction partners, which may explain pleiotropic effects of CNVs on schizophrenia risk and offer a broader field for interventions.PMID:38493363 | DOI:10.1080/15622975.2024.2327027 (Source: The World Journal of Biological Psychiatry)
Source: The World Journal of Biological Psychiatry - March 17, 2024 Category: Psychiatry Authors: Friederike Ehrhart Ana Silva Therese van Amelsvoort Emma vonScheibler Chris Evelo David E J Linden Source Type: research
Copy number variant risk loci for schizophrenia converge on the BDNF pathway
Conclusions: Our findings suggest that specific pathways - BDNF signaling - are critical contributors to schizophrenia risk conferred by rare CNVs. Our approach highlights the importance of not only investigating deleted or duplicated genes within pathogenic CNV loci, but also study their direct interaction partners, which may explain pleiotropic effects of CNVs on schizophrenia risk and offer a broader field for interventions.PMID:38493363 | DOI:10.1080/15622975.2024.2327027 (Source: The World Journal of Biological Psychiatry)
Source: The World Journal of Biological Psychiatry - March 17, 2024 Category: Psychiatry Authors: Friederike Ehrhart Ana Silva Therese van Amelsvoort Emma vonScheibler Chris Evelo David E J Linden Source Type: research
