Vitamin D levels of pregnant immigrant women and developmental disorders of language, learning and coordination in offspring
by Bianca Arrhenius, Helj ä-Marja Surcel, Susanna Hinkka Yli-Salomäki, Alan Brown, Keely Cheslack-Postava, Andre Sourander BackgroundPrenatal vitamin D deficiency is a common health concern among immigrants. No previous studies have examined the associations between prenatal vitamin D levels and developmental disorders of language, scholastic skills, and coordination in an immigrant sample. MethodsThe sample included 542 immigrant mothers of cases with language, scholastic, coordination or mixed developmental disorders, 443 immigrant mothers of controls without these disorders and 542 Finnish mothers of controls. Materna...
Source: PLoS One - February 29, 2024 Category: Biomedical Science Authors: Bianca Arrhenius Source Type: research

Mini-Review on Vitamin D in Pediatric Population and its Role in Respiratory and Atopic Disorders
Mini Rev Med Chem. 2024 Feb 20. doi: 10.2174/0113895575284873240212045431. Online ahead of print.ABSTRACTIn recent years, our comprehension of the function of vitamin D has significantly evolved. The ubiquitous presence of the vitamin D receptor (Vitamin D Receptor- VDR) in the body has led to its redefinition from a steroidal hormone primarily involved in skeletal functions to a hormone with pleiotropic effects, exerting its influence on the circulatory, nervous, and immune systems. This has prompted investigations into its potential use in preventing and treating chronic metabolic disorders, cardiovascular diseases, infe...
Source: Mini Reviews in Medicinal Chemistry - February 28, 2024 Category: Chemistry Authors: Cristiana Indolfi Angela Klain Giulio Dinardo Fabio Decimo Maria Maddalena Marrapodi Amelia Licari Michele Miraglia Del Giudice Source Type: research

Exploring the link between vitamin D deficiency and obstructive sleep apnea: A comprehensive review
J Sleep Res. 2024 Feb 27:e14166. doi: 10.1111/jsr.14166. Online ahead of print.ABSTRACTDespite the high prevalence and significant health burden of obstructive sleep apnea (OSA), its underlying pathophysiology remains incompletely understood. This comprehensive review explores the emerging connection between vitamin D deficiency and OSA, discusses potential mechanisms underlying this association, and explores the therapeutic implications of these findings. Recent research has consistently highlighted the high incidence of vitamin D deficiency among patients with OSA, which often occurs independently of geographical locatio...
Source: Journal of Sleep Research - February 28, 2024 Category: Sleep Medicine Authors: Nan Yao Chenyuan Ma Ruixue Dou Chao Shen Ye Yuan Wei Li Jun Qu Source Type: research

Paraspeckle protein NONO attenuates vascular calcification by inhibiting bone morphogenetic protein 2 transcription
Kidney Int. 2024 Feb 26:S0085-2538(24)00162-5. doi: 10.1016/j.kint.2024.01.039. Online ahead of print.ABSTRACTVascular calcification is a pathological process commonly associated with atherosclerosis, chronic kidney disease, and diabetes. Paraspeckle protein NONO is a multifunctional RNA/DNA binding protein involved in many nuclear biological processes but its role in vascular calcification remains unclear. Here, we observed that NONO expression was decreased in calcified arteries of mice and patients with CKD. We generated smooth muscle-specific NONO-knockout mice and established three different mouse models of vascular c...
Source: Atherosclerosis - February 28, 2024 Category: Cardiology Authors: Yue Lu Linlin Meng Ruiqing Ren Xinlu Wang Wenhai Sui Fei Xue Lin Xie Ang Chen Yuxia Zhao Jianmin Yang Wencheng Zhang Xiao Yu Bo Xi Feng Xu Meng Zhang Yun Zhang Cheng Zhang Source Type: research

Mini-Review on Vitamin D in Pediatric Population and its Role in Respiratory and Atopic Disorders
Mini Rev Med Chem. 2024 Feb 20. doi: 10.2174/0113895575284873240212045431. Online ahead of print.ABSTRACTIn recent years, our comprehension of the function of vitamin D has significantly evolved. The ubiquitous presence of the vitamin D receptor (Vitamin D Receptor- VDR) in the body has led to its redefinition from a steroidal hormone primarily involved in skeletal functions to a hormone with pleiotropic effects, exerting its influence on the circulatory, nervous, and immune systems. This has prompted investigations into its potential use in preventing and treating chronic metabolic disorders, cardiovascular diseases, infe...
Source: Mini Reviews in Medicinal Chemistry - February 28, 2024 Category: Chemistry Authors: Cristiana Indolfi Angela Klain Giulio Dinardo Fabio Decimo Maria Maddalena Marrapodi Amelia Licari Michele Miraglia Del Giudice Source Type: research

A Short-Term Zinc-Deficient Diet Maintains Serum Calcium Concentrations through Ca Absorption-Related Gene Expression in Rats
J Nutr Sci Vitaminol (Tokyo). 2024;70(1):82-87. doi: 10.3177/jnsv.70.82.ABSTRACTWe investigated the effects of short-term dietary zinc deficiency on zinc and calcium metabolism. Four-week-old male Wistar rats were divided into two pair-fed groups for a 1-wk treatment: zinc-deficient group (ZD, 1 ppm); control group (PF, 30 ppm). The mRNA expression of zinc transporters, such as Slc39a (Zip) 4, Zip5, Zip10, and Slc30a (ZnT) 1, in various tissues (liver, kidney, and duodenum) quickly responded to dietary zinc deficiency. Although there was no significant difference in serum calcium concentrations between the PF and ZD groups...
Source: Journal of Nutritional Science and Vitaminology - February 28, 2024 Category: Nutrition Authors: Takako Suzuki Kazuharu Suzuki Jun Takahashi Yukio Nakamura Source Type: research

Exploring the link between vitamin D deficiency and obstructive sleep apnea: A comprehensive review
J Sleep Res. 2024 Feb 27:e14166. doi: 10.1111/jsr.14166. Online ahead of print.ABSTRACTDespite the high prevalence and significant health burden of obstructive sleep apnea (OSA), its underlying pathophysiology remains incompletely understood. This comprehensive review explores the emerging connection between vitamin D deficiency and OSA, discusses potential mechanisms underlying this association, and explores the therapeutic implications of these findings. Recent research has consistently highlighted the high incidence of vitamin D deficiency among patients with OSA, which often occurs independently of geographical locatio...
Source: Journal of Sleep Research - February 28, 2024 Category: Sleep Medicine Authors: Nan Yao Chenyuan Ma Ruixue Dou Chao Shen Ye Yuan Wei Li Jun Qu Source Type: research

A Short-Term Zinc-Deficient Diet Maintains Serum Calcium Concentrations through Ca Absorption-Related Gene Expression in Rats
J Nutr Sci Vitaminol (Tokyo). 2024;70(1):82-87. doi: 10.3177/jnsv.70.82.ABSTRACTWe investigated the effects of short-term dietary zinc deficiency on zinc and calcium metabolism. Four-week-old male Wistar rats were divided into two pair-fed groups for a 1-wk treatment: zinc-deficient group (ZD, 1 ppm); control group (PF, 30 ppm). The mRNA expression of zinc transporters, such as Slc39a (Zip) 4, Zip5, Zip10, and Slc30a (ZnT) 1, in various tissues (liver, kidney, and duodenum) quickly responded to dietary zinc deficiency. Although there was no significant difference in serum calcium concentrations between the PF and ZD groups...
Source: Journal of Nutritional Science and Vitaminology - February 28, 2024 Category: Nutrition Authors: Takako Suzuki Kazuharu Suzuki Jun Takahashi Yukio Nakamura Source Type: research

Exploring the link between vitamin D deficiency and obstructive sleep apnea: A comprehensive review
J Sleep Res. 2024 Feb 27:e14166. doi: 10.1111/jsr.14166. Online ahead of print.ABSTRACTDespite the high prevalence and significant health burden of obstructive sleep apnea (OSA), its underlying pathophysiology remains incompletely understood. This comprehensive review explores the emerging connection between vitamin D deficiency and OSA, discusses potential mechanisms underlying this association, and explores the therapeutic implications of these findings. Recent research has consistently highlighted the high incidence of vitamin D deficiency among patients with OSA, which often occurs independently of geographical locatio...
Source: Journal of Sleep Research - February 28, 2024 Category: Sleep Medicine Authors: Nan Yao Chenyuan Ma Ruixue Dou Chao Shen Ye Yuan Wei Li Jun Qu Source Type: research

A Short-Term Zinc-Deficient Diet Maintains Serum Calcium Concentrations through Ca Absorption-Related Gene Expression in Rats
J Nutr Sci Vitaminol (Tokyo). 2024;70(1):82-87. doi: 10.3177/jnsv.70.82.ABSTRACTWe investigated the effects of short-term dietary zinc deficiency on zinc and calcium metabolism. Four-week-old male Wistar rats were divided into two pair-fed groups for a 1-wk treatment: zinc-deficient group (ZD, 1 ppm); control group (PF, 30 ppm). The mRNA expression of zinc transporters, such as Slc39a (Zip) 4, Zip5, Zip10, and Slc30a (ZnT) 1, in various tissues (liver, kidney, and duodenum) quickly responded to dietary zinc deficiency. Although there was no significant difference in serum calcium concentrations between the PF and ZD groups...
Source: Journal of Nutritional Science and Vitaminology - February 28, 2024 Category: Nutrition Authors: Takako Suzuki Kazuharu Suzuki Jun Takahashi Yukio Nakamura Source Type: research