Association between serum 25 ‐hydroxyvitamin D level and inflammatory markers in hemodialysis‐treated patients
ConclusionCollectively, serum 25(OH)D level has a negative correlation with inflammatory markers. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - April 23, 2024 Category: Allergy & Immunology Authors: Chunlei Luo, Xueyan Bian, Lingling Bao, Qingqing Xu, Chunyang Ji Tags: ORIGINAL ARTICLE Source Type: research

Phenomewide Association Study of Health Outcomes Associated With the Genetic Correlates of 25 Hydroxyvitamin D Concentration and Vitamin D Binding Protein Concentration
We examined the predictive properties of PGS25OHD, and two scores related to DBP concentration with respect to 1322 health-related phenotypes and 315 laboratory-measured phenotypes from electronic health records. In those with European ancestry: (a) the PGS25OHD and PGSDBP scores, and individual SNPs rs4588 and rs7041 were associated with both 25OHD concentration and 1,25 dihydroxyvitamin D concentrations; (b) higher PGS25OHD was associated with decreased concentrations of triglycerides and cholesterol, and reduced risks of vitamin D deficiency, disorders of lipid metabolism, and diabetes. In general, the findings for the ...
Source: Twin Research and Human Genetics - April 22, 2024 Category: Genetics & Stem Cells Authors: Hailey A Kresge Freida Blostein Slavina Goleva Clara Albi ñana Joana A Revez Naomi R Wray Bjarni J Vilhj álmsson Zhihong Zhu John J McGrath Lea K Davis Source Type: research

Phenomewide Association Study of Health Outcomes Associated With the Genetic Correlates of 25 Hydroxyvitamin D Concentration and Vitamin D Binding Protein Concentration
We examined the predictive properties of PGS25OHD, and two scores related to DBP concentration with respect to 1322 health-related phenotypes and 315 laboratory-measured phenotypes from electronic health records. In those with European ancestry: (a) the PGS25OHD and PGSDBP scores, and individual SNPs rs4588 and rs7041 were associated with both 25OHD concentration and 1,25 dihydroxyvitamin D concentrations; (b) higher PGS25OHD was associated with decreased concentrations of triglycerides and cholesterol, and reduced risks of vitamin D deficiency, disorders of lipid metabolism, and diabetes. In general, the findings for the ...
Source: Twin Research and Human Genetics - April 22, 2024 Category: Genetics & Stem Cells Authors: Hailey A Kresge Freida Blostein Slavina Goleva Clara Albi ñana Joana A Revez Naomi R Wray Bjarni J Vilhj álmsson Zhihong Zhu John J McGrath Lea K Davis Source Type: research

Vitamin D-associated genetic variants in the Brazilian population: Investigating potential instruments for Mendelian randomization
CONCLUSIONS: More research is needed to validate sound proxies for vitamin D levels in Brazil, for example, prioritizing GC rather than VDR.PMID:38648345 | DOI:10.7705/biomedica.6972 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - April 22, 2024 Category: International Medicine & Public Health Authors: Caroline De Souza Silverio Carolina Bonilla Source Type: research

Phenomewide Association Study of Health Outcomes Associated With the Genetic Correlates of 25 Hydroxyvitamin D Concentration and Vitamin D Binding Protein Concentration
We examined the predictive properties of PGS25OHD, and two scores related to DBP concentration with respect to 1322 health-related phenotypes and 315 laboratory-measured phenotypes from electronic health records. In those with European ancestry: (a) the PGS25OHD and PGSDBP scores, and individual SNPs rs4588 and rs7041 were associated with both 25OHD concentration and 1,25 dihydroxyvitamin D concentrations; (b) higher PGS25OHD was associated with decreased concentrations of triglycerides and cholesterol, and reduced risks of vitamin D deficiency, disorders of lipid metabolism, and diabetes. In general, the findings for the ...
Source: Twin Research and Human Genetics - April 22, 2024 Category: Genetics & Stem Cells Authors: Hailey A Kresge Freida Blostein Slavina Goleva Clara Albi ñana Joana A Revez Naomi R Wray Bjarni J Vilhj álmsson Zhihong Zhu John J McGrath Lea K Davis Source Type: research

Vitamin D-associated genetic variants in the Brazilian population: Investigating potential instruments for Mendelian randomization
CONCLUSIONS: More research is needed to validate sound proxies for vitamin D levels in Brazil, for example, prioritizing GC rather than VDR.PMID:38648345 | DOI:10.7705/biomedica.6972 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - April 22, 2024 Category: International Medicine & Public Health Authors: Caroline De Souza Silverio Carolina Bonilla Source Type: research

Vitamin D: Synthesis, deficiency, polymorphisms and resistance to its action in Latin American countries
Biomedica. 2024 Mar 31;44(1):5-9. doi: 10.7705/biomedica.7477.NO ABSTRACTPMID:38648341 | DOI:10.7705/biomedica.7477 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - April 22, 2024 Category: International Medicine & Public Health Authors: Pedro Nel Rueda-Plata Source Type: research

Phenomewide Association Study of Health Outcomes Associated With the Genetic Correlates of 25 Hydroxyvitamin D Concentration and Vitamin D Binding Protein Concentration
We examined the predictive properties of PGS25OHD, and two scores related to DBP concentration with respect to 1322 health-related phenotypes and 315 laboratory-measured phenotypes from electronic health records. In those with European ancestry: (a) the PGS25OHD and PGSDBP scores, and individual SNPs rs4588 and rs7041 were associated with both 25OHD concentration and 1,25 dihydroxyvitamin D concentrations; (b) higher PGS25OHD was associated with decreased concentrations of triglycerides and cholesterol, and reduced risks of vitamin D deficiency, disorders of lipid metabolism, and diabetes. In general, the findings for the ...
Source: Twin Research and Human Genetics - April 22, 2024 Category: Genetics & Stem Cells Authors: Hailey A Kresge Freida Blostein Slavina Goleva Clara Albi ñana Joana A Revez Naomi R Wray Bjarni J Vilhj álmsson Zhihong Zhu John J McGrath Lea K Davis Source Type: research

Vitamin D-associated genetic variants in the Brazilian population: Investigating potential instruments for Mendelian randomization
CONCLUSIONS: More research is needed to validate sound proxies for vitamin D levels in Brazil, for example, prioritizing GC rather than VDR.PMID:38648345 | DOI:10.7705/biomedica.6972 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - April 22, 2024 Category: International Medicine & Public Health Authors: Caroline De Souza Silverio Carolina Bonilla Source Type: research

Vitamin D: Synthesis, deficiency, polymorphisms and resistance to its action in Latin American countries
Biomedica. 2024 Mar 31;44(1):5-9. doi: 10.7705/biomedica.7477.NO ABSTRACTPMID:38648341 | DOI:10.7705/biomedica.7477 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - April 22, 2024 Category: International Medicine & Public Health Authors: Pedro Nel Rueda-Plata Source Type: research

Phenomewide Association Study of Health Outcomes Associated With the Genetic Correlates of 25 Hydroxyvitamin D Concentration and Vitamin D Binding Protein Concentration
We examined the predictive properties of PGS25OHD, and two scores related to DBP concentration with respect to 1322 health-related phenotypes and 315 laboratory-measured phenotypes from electronic health records. In those with European ancestry: (a) the PGS25OHD and PGSDBP scores, and individual SNPs rs4588 and rs7041 were associated with both 25OHD concentration and 1,25 dihydroxyvitamin D concentrations; (b) higher PGS25OHD was associated with decreased concentrations of triglycerides and cholesterol, and reduced risks of vitamin D deficiency, disorders of lipid metabolism, and diabetes. In general, the findings for the ...
Source: Twin Research and Human Genetics - April 22, 2024 Category: Genetics & Stem Cells Authors: Hailey A Kresge Freida Blostein Slavina Goleva Clara Albi ñana Joana A Revez Naomi R Wray Bjarni J Vilhj álmsson Zhihong Zhu John J McGrath Lea K Davis Source Type: research

Vitamin D-associated genetic variants in the Brazilian population: Investigating potential instruments for Mendelian randomization
CONCLUSIONS: More research is needed to validate sound proxies for vitamin D levels in Brazil, for example, prioritizing GC rather than VDR.PMID:38648345 | DOI:10.7705/biomedica.6972 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - April 22, 2024 Category: International Medicine & Public Health Authors: Caroline De Souza Silverio Carolina Bonilla Source Type: research

Vitamin D: Synthesis, deficiency, polymorphisms and resistance to its action in Latin American countries
Biomedica. 2024 Mar 31;44(1):5-9. doi: 10.7705/biomedica.7477.NO ABSTRACTPMID:38648341 | DOI:10.7705/biomedica.7477 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - April 22, 2024 Category: International Medicine & Public Health Authors: Pedro Nel Rueda-Plata Source Type: research