Vitamin D status of pregnant women with obesity in the United Kingdom and its association with pregnancy outcomes: a secondary analysis of the UPBEAT study
Br J Nutr. 2024 Apr 18:1-28. doi: 10.1017/S0007114524000862. Online ahead of print.ABSTRACTPrenatal vitamin D deficiency is widely reported and may affect perinatal outcomes. In this secondary analysis of the UK Pregnancies Better Eating and Activity Trial (UPBEAT), we examined vitamin D status and its relationship with selected pregnancy outcomes in women with obesity (BMI≥30kg/m2) from multi-ethnic inner-city settings in the UK. Determinants of vitamin D status at a mean of 17±1 weeks' gestation were assessed using multivariable linear regression and reported as percent differences in serum hydroxyvitamin D (25(OH)D)....
Source: The British Journal of Nutrition - April 18, 2024 Category: Nutrition Authors: Karen M O'Callaghan Katarzyna G Nowak Kathryn V Dalrymple Lucilla Poston Jessica Rigutto-Farebrother Ola F Quotah Sara L White Angela C Flynn UPBEAT Consortium Source Type: research

Gene expression profiling of vitamin D metabolism enzymes in leukemia and lymphoma patients: molecular aspect interplay of VDR, CYP2R1, and CYP24A1
CONCLUSION: The study revealed a noteworthy difference in VDR protein levels between men and women. The highest mean CYP24A1 protein levels were observed in the age group > 60 years. This study found a significant, moderately positive correlation between VDR protein levels and CYP24A1 protein levels in the male and vitamin D sufficiency groups. In addition, a significant positive correlation was found between VDR mRNA levels and CYP2R1 mRNA levels, VDR mRNA levels and CYP2R1 mRNA levels, and CYP2R1 mRNA levels and CYP24A1 mRNA levels. However, the expression of these genes does not correlate with the protein levels of i...
Source: Molecular Biology Reports - April 17, 2024 Category: Molecular Biology Authors: Anggraini Iriani Andhika Rachman Marsya Kaila Fatina Rizka Kurnia Gemilang Andi Trisnandi Media Fitri Isma Nugraha Source Type: research

Impact of supplementation with iron-folic acid (IFA) and vitamin D3 compared with IFA alone on haemoglobin levels in elderly people with mild-to-moderate anaemia: protocol for the double-blind, randomised, placebo-controlled Iron and vitamin D trial in Elderly Anemia (IDEA)
This study is a community-based, double-blind, placebo-controlled, randomised trial. The study will be done in the Kalyani municipality area. Individuals aged ≥60 years with mild-to-moderate anaemia and normal vitamin D3 levels will be randomised into the intervention (IFA and vitamin D3 supplementation) group or the control group (IFA and olive oil as placebo). All medications will be self-administered. Follow-up will be done on a weekly basis for 12 weeks. The calculated sample size is 150 in each arm. Block randomisation will be done. The primary outcome is change in haemoglobin levels from baseline to 12 weeks. Seco...
Source: BMJ Open - April 16, 2024 Category: General Medicine Authors: Ahamed, F., Jaiswal, A., Sahoo, S., Ghosh, T., Kaur, A., Rehman, T., Goswami, K. Tags: Open access, Geriatric medicine Source Type: research

Monitoring the utilization and effectiveness of Iron and Vitamin D supplementations program and its predictive factors in high schools ’ girls in Qom, Iran
Conclusion:The inadequate and incomplete rate of IVDSP in Qom was high and more than 60% of distributed supplementations have been wasted. Our results showed that students who were participated in educational orientation classes were more successful and eager in iron and vitamin D3 consumption.  Therefore, it is recommended to increase interventions at individual, interpersonal, intra-organizational and inter-organizational levels in order to fully support the program and ultimately increase the efficiency of the program.  (Source: Journal of Preventive Medicine and Hygiene)
Source: Journal of Preventive Medicine and Hygiene - April 15, 2024 Category: International Medicine & Public Health Authors: Abolfazl Mohammadbeigi, Dr Source Type: research

Ambient ultraviolet-B radiation, supplements and other factors interact to impact vitamin D status differently depending on ethnicity: a cross-sectional study
Many determinants of vitamin D status have been well-described, yet supplementation guidelines largely follow a one-size-for-all model and deficiency remains common. We hypothesised that accounting accurately for ultraviolet-B (UVB) radiation and considering interactions could advance understanding of vitamin D status. (Source: Clinical Nutrition)
Source: Clinical Nutrition - April 11, 2024 Category: Nutrition Authors: Margaret M. Brennan, Jos van Geffen, Michiel van Weele, Lina Zgaga, Rasha Shraim Source Type: research

Vitamin D-A New Therapeutic Target in the Management of Type 2 Diabetes Patients
Conclusions: Vitamin D influences almost every system and organ in the body, so it should be a routine test for all patients with DM to correct the deficiency and prevent other diseases and complications.PMID:38592202 | DOI:10.3390/jcm13051390 (Source: Molecular Medicine)
Source: Molecular Medicine - April 9, 2024 Category: Molecular Biology Authors: Oana Albai Adina Braha Bogdan Timar Ioana Golu Romulus Timar Source Type: research

Revisiting the association between vitamin D deficiency and active tuberculosis: A prospective case-control study in Taiwan
CONCLUSIONS: VDD is an independent risk factor for incident active TB. Future randomized trials examining the effect of vitamin D supplementation on TB incidence should focus on people with a low BMI or other risk factors to maximize the statistical power.PMID:38594108 | DOI:10.1016/j.jmii.2024.03.005 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - April 9, 2024 Category: Microbiology Authors: Meng-Shiuan Hsu Tzu-Chien Chung Ping-Huai Wang Shih-Lung Cheng Yen-Wen Wu Jung-Cheng Hsu Bing-Hsiean Tzeng Heng-Hsu Lin Chung-Ming Tu Fang-Yeh Chu Chi-Tai Fang Source Type: research

Revisiting the association between vitamin D deficiency and active tuberculosis: A prospective case-control study in Taiwan
CONCLUSIONS: VDD is an independent risk factor for incident active TB. Future randomized trials examining the effect of vitamin D supplementation on TB incidence should focus on people with a low BMI or other risk factors to maximize the statistical power.PMID:38594108 | DOI:10.1016/j.jmii.2024.03.005 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - April 9, 2024 Category: Microbiology Authors: Meng-Shiuan Hsu Tzu-Chien Chung Ping-Huai Wang Shih-Lung Cheng Yen-Wen Wu Jung-Cheng Hsu Bing-Hsiean Tzeng Heng-Hsu Lin Chung-Ming Tu Fang-Yeh Chu Chi-Tai Fang Source Type: research

Revisiting the association between vitamin D deficiency and active tuberculosis: A prospective case-control study in Taiwan
CONCLUSIONS: VDD is an independent risk factor for incident active TB. Future randomized trials examining the effect of vitamin D supplementation on TB incidence should focus on people with a low BMI or other risk factors to maximize the statistical power.PMID:38594108 | DOI:10.1016/j.jmii.2024.03.005 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - April 9, 2024 Category: Microbiology Authors: Meng-Shiuan Hsu Tzu-Chien Chung Ping-Huai Wang Shih-Lung Cheng Yen-Wen Wu Jung-Cheng Hsu Bing-Hsiean Tzeng Heng-Hsu Lin Chung-Ming Tu Fang-Yeh Chu Chi-Tai Fang Source Type: research

Revisiting the association between vitamin D deficiency and active tuberculosis: A prospective case-control study in Taiwan
CONCLUSIONS: VDD is an independent risk factor for incident active TB. Future randomized trials examining the effect of vitamin D supplementation on TB incidence should focus on people with a low BMI or other risk factors to maximize the statistical power.PMID:38594108 | DOI:10.1016/j.jmii.2024.03.005 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - April 9, 2024 Category: Microbiology Authors: Meng-Shiuan Hsu Tzu-Chien Chung Ping-Huai Wang Shih-Lung Cheng Yen-Wen Wu Jung-Cheng Hsu Bing-Hsiean Tzeng Heng-Hsu Lin Chung-Ming Tu Fang-Yeh Chu Chi-Tai Fang Source Type: research

Effect of Antenatal Oral Vitamin D Supplementation on Serum 25(OH)D Concentration in Exclusively Breastfed Infants at 6 Months of age - A Randomized Double-Blind Placebo-Controlled Trial
CONCLUSIONS: Oral supplementation of vitamin D3 to pregnant women in the third trimester prevents severe hypovitaminosis D in the EBF infants at 6-months of age.PMID:38584410 (Source: Indian Pediatrics)
Source: Indian Pediatrics - April 8, 2024 Category: Pediatrics Authors: Prashant Prabhakar M M A Faridi Anju Aggarwal Rachna Aggarwal S V Madhu Rajeev Malhotra Source Type: research

Effect of Antenatal Oral Vitamin D Supplementation on Serum 25(OH)D Concentration in Exclusively Breastfed Infants at 6 Months of age - A Randomized Double-Blind Placebo-Controlled Trial
CONCLUSIONS: Oral supplementation of vitamin D3 to pregnant women in the third trimester prevents severe hypovitaminosis D in the EBF infants at 6-months of age.PMID:38584410 (Source: Indian Pediatrics)
Source: Indian Pediatrics - April 8, 2024 Category: Pediatrics Authors: Prashant Prabhakar M M A Faridi Anju Aggarwal Rachna Aggarwal S V Madhu Rajeev Malhotra Source Type: research

Effect of Antenatal Oral Vitamin D Supplementation on Serum 25(OH)D Concentration in Exclusively Breastfed Infants at 6 Months of age - A Randomized Double-Blind Placebo-Controlled Trial
CONCLUSIONS: Oral supplementation of vitamin D3 to pregnant women in the third trimester prevents severe hypovitaminosis D in the EBF infants at 6-months of age.PMID:38584410 (Source: Indian Pediatrics)
Source: Indian Pediatrics - April 8, 2024 Category: Pediatrics Authors: Prashant Prabhakar M M A Faridi Anju Aggarwal Rachna Aggarwal S V Madhu Rajeev Malhotra Source Type: research

Association between prenatal vitamin D deficiency with dental caries in infants and children: a systematic review and meta-analysis
Prenatal vitamin D (PVD) is a vital micronutrient for dental caries (DCs). The association between prenatal vitamin D deficiencies (PVDD) and DCs in children has been conflicting in different reports. This met... (Source: BMC Pregnancy and Childbirth)
Source: BMC Pregnancy and Childbirth - April 8, 2024 Category: OBGYN Authors: Mansour Bahardoust, Salar Salari, Nader Ghotbi, Elham Rahimpour, Meisam Haghmoradi, Homan Alipour and Mahsa Soleimani Tags: Research Source Type: research

Iodine Nutrition, Thyroid-stimulating Hormone, and Related Factors of Postpartum Women from three Different Areas in China: A Cross-sectional Survey
CONCLUSION: The mothers in the present study had no iodine deficiency. Region, area type, BMI, and VD may be related to the iodine status or TSH levels.PMID:38582990 | DOI:10.3967/bes2024.029 (Source: Biomedical and Environmental Sciences : BES)
Source: Biomedical and Environmental Sciences : BES - April 7, 2024 Category: Biomedical Science Authors: Xiao Yun Shan Yan Zou Li Chun Huang Shan Jiang Wei Wen Zhou Qiu Lan Qin Chang Qing Liu Xiao Yan Luo Jia Xi Lu De Qian Mao Min Li Zhen Yu Yang Li Chen Yang Source Type: research