US researchers find vitamin B3 prevents glaucoma
Researchers from The Jackson Laboratory (JAX), US, have found that vitamin B3, when added to drinking water, is effective at preventing glaucoma. (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - February 20, 2017 Category: Pharmaceuticals Source Type: news

Adding vitamin B3 to water may prevent glaucoma
In a study on mice, scientists from The Jackson Laboratory in Bar Harbor, Maine, found it helped to keep their eyes healthier for longer - reducing their risk of developing the condition. (Source: the Mail online | Health)
Source: the Mail online | Health - February 17, 2017 Category: Consumer Health News Source Type: news

[Report] Vitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice
Glaucomas are neurodegenerative diseases that cause vision loss, especially in the elderly. The mechanisms initiating glaucoma and driving neuronal vulnerability during normal aging are unknown. Studying glaucoma-prone mice, we show that mitochondrial abnormalities are an early driver of neuronal dysfunction, occurring before detectable degeneration. Retinal levels of nicotinamide adenine dinucleotide (NAD+, a key molecule in energy and redox metabolism) decrease with age and render aging neurons vulnerable to disease-related insults. Oral administration of the NAD+ precursor nicotinamide (vitamin B3), and/or gene therapy ...
Source: ScienceNOW - February 16, 2017 Category: Science Authors: Pete A. Williams Source Type: news

[This Week in Science] Vitamin B3 protects mice from glaucoma
Author: Priscilla Kelly (Source: ScienceNOW)
Source: ScienceNOW - February 16, 2017 Category: Science Authors: Priscilla Kelly Tags: Glaucoma Source Type: news

On the Verge of Immortality, Or Are We Stuck with Death? A New Direction For Research Could Provide the Answers--and More
How long can human beings live? Is there an outside limit? Do we know enough about aging to break through possible biological barriers? Is the current approach to curing "age associated diseases" like Alzheimer's flawed? Experts are sharply divided. In 1962 eminent biologist Leonard Hayflick discovered that normal human fetal cells replicate a limited number of times. This phenomenon promptly acquired the moniker the "Hayflick Limit." Later, biologists Calvin Harley and Carol Greider provided the molecular explanation for the Hayflick limit with their discovery that telomeres, the DNA biological material in every cell of ...
Source: Healthy Living - The Huffington Post - January 13, 2017 Category: Consumer Health News Source Type: news

People with forms of early-onset Parkinson's disease may benefit from boosting niacin in diet, research suggests
People with certain forms of early-onset Parkinson's disease may benefit from boosting the amount of niacin in their diet, according to new research from the University of Leicester. (Source: Parkinson's Disease News From Medical News Today)
Source: Parkinson's Disease News From Medical News Today - January 12, 2017 Category: Neurology Tags: Parkinson's Disease Source Type: news

People with forms of early-onset Parkinson's disease may benefit from boosting niacin in diet, research suggests
A new study is strengthening the therapeutic potential for dietary interventions in Parkinson ' s disease, suggesting that these patients may benefit from a boost in niacin, which is found in some nuts and meat. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - January 10, 2017 Category: Science Source Type: news

Why Knowing Your Triglyceride Number Matters
Many of us can rattle off our latest cholesterol number at the drop of a hat. Keeping an eye on your cholesterol is important but there's another number you also should have memorized - your triglycerides. However, if asked about our triglyceride number, most of us have little to know idea what it is. That's too bad because our triglyceride number reveals quite a bit of how healthy we are or not. The good news is there are many steps we can take to get it in a healthier range starting today. What are triglycerides? Triglycerides (TG) are the most common type of fat in the body and are an important measure of heart health...
Source: Healthy Living - The Huffington Post - October 17, 2016 Category: Consumer Health News Source Type: news

First human clinical trial for nicotinamide riboside
In the first controlled clinical trial of nicotinamide riboside (NR), a newly discovered form of Vitamin B3, researchers have shown that the compound is safe for humans and increases levels of a cell metabolite that is critical for cellular energy production and protection against stress and DNA damage. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - October 10, 2016 Category: Science Source Type: news

First human clinical trial for nicotinamide riboside
In the first controlled clinical trial of nicotinamide riboside (NR), a newly discovered form of Vitamin B3, researchers have shown that the compound is safe for humans and increases levels of a cell metabolite that is critical for cellular energy production and protection against stress and DNA damage. Studies in mice have shown that boosting the levels of this cell metabolite - known as NAD+ - can produce multiple health benefits, (Source: World Pharma News)
Source: World Pharma News - October 10, 2016 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

First human clinical trial for nicotinamide riboside
(University of Iowa Health Care) In the first controlled clinical trial of nicotinamide riboside (NR), a newly discovered form of vitamin B3, researchers have shown that the compound is safe for humans and increases levels of a cell metabolite that is critical for cellular energy production and protection against stress and DNA damage. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 10, 2016 Category: Global & Universal Source Type: news

Eczema risk 'reduced by a third' by eating fish and mushrooms during pregnancy
High levels of nicotinamide - a form of Vitamin B3 - in pregnancy lowers the risk of one-year-old children by 30 per cent, researchers from the University of Southampton found. (Source: the Mail online | Health)
Source: the Mail online | Health - September 23, 2016 Category: Consumer Health News Source Type: news

Want to stop YOUR child from getting eczema? Eating fish, chicken and mushrooms during pregnancy 'reduces the risk by a third'
High levels of nicotinamide - a form of Vitamin B3 - in pregnancy lowers the risk of one-year-old children by 30 per cent, researchers from the University of Southampton found. (Source: the Mail online | Health)
Source: the Mail online | Health - September 23, 2016 Category: Consumer Health News Source Type: news

[Research Article] NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice
Adult stem cells (SCs) are essential for tissue maintenance and regeneration yet are susceptible to senescence during aging. We demonstrate the importance of the amount of the oxidized form of cellular nicotinamide adenine dinucleotide (NAD+) and its effect on mitochondrial activity as a pivotal switch to modulate muscle SC (MuSC) senescence. Treatment with the NAD+ precursor nicotinamide riboside (NR) induced the mitochondrial unfolded protein response and synthesis of prohibitin proteins, and this rejuvenated MuSCs in aged mice. NR also prevented MuSC senescence in the mdx (C57BL/10ScSn-Dmdmdx/J) mouse model of muscular ...
Source: ScienceNOW - June 16, 2016 Category: Science Authors: Hongbo Zhang Source Type: news

Vitamin nicotinamide riboside protects mice from diabetes complications
A naturally occurring vitamin, nicotinamide riboside, can improve metabolic symptoms and prevent peripheral nerve damage in mouse models of diabetes, according to a new study. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 27, 2016 Category: Science Source Type: news