NIH Director's Seminar Series: Neuronal-origin extracellular vesicles in the circulation as a source of biomarkers for brain diseases
Extracellular Vesicles enriched for neuronal origin (NEVs) can be isolated from plasma by immunoaffinity capture. NEVs provide biomarkers for diagnosis, prognosis, disease monitoring, and therapeutic response in Alzheimer ’ s disease and related dementias (AD/ADRD), and, increasingly, other neurologic and psychiatric disorders. NEV biomarkers for preclinical AD have been validated in large longitudinal cohorts, such as the Baltimore Longitudinal Study of Aging. Moreover, NEV biomarkers can identify clinical subgroups (e.g., Parkinson ’ s disease patients with cognitive impairment), facilitating the development of Preci...
Source: Videocast - All Events - March 29, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
