Energizing sick mitochondria with vitamin B3
(University of Helsinki) The researchers of the University of Helsinki, Finland, and École Polytechnique Fédérale de Lausanne, Switzerland, have shown that vitamin B3 form nicotinamide riboside can slow down the progression of mitochondrial disease, suggesting its potential as a novel therapy approach to adult-onset mitochondrial muscle diseases. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 7, 2014 Category: Biology Source Type: news

Jubilant Life to hike Niacin prices by 18%
Drug-maker Jubilant Life Sciences today announced a price increase of 18 per cent for Niacin feed-grade, with immediate effect. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - March 13, 2014 Category: Pharmaceuticals Source Type: news

Could niacin be the fountain of youth?
The vitamin niacin has a life-prolonging effect, as Michael Ristow has demonstrated in roundworms. From his study, the ETH-Zurich professor also concludes that so-called reactive oxygen species are healthy, not only disagreeing with the general consensus, but also many of his peers. Who would not want to live a long and healthy life? A freely available food supplement could help in this respect, scientists from ETH Zurich have demonstrated in roundworms... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 2, 2013 Category: Consumer Health News Tags: Nutrition / Diet Source Type: news

Niacin, the fountain of youth
(ETH Zurich) The vitamin niacin has a life-prolonging effect, as Michael Ristow has demonstrated in roundworms. From his study, the ETH-Zurich professor also concludes that so-called reactive oxygen species are healthy, not only disagreeing with the general consensus, but also many of his peers. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 30, 2013 Category: Global & Universal Source Type: news

Nutrition 101: Niacin
(HealthCastle.com) Niacin, also known as vitamin B3, is one of 8 B vitamins.  All of the B vitamins are water-soluble, meaning that the body does not store them but excretes them in the urine. Other names for niacin include nicotinic acid and nicotinamide / niacinamide.  read more (Source: HealthCastle.com Nutrition Tips - written by Registered Dietitians)
Source: HealthCastle.com Nutrition Tips - written by Registered Dietitians - September 7, 2013 Category: Nutrition Source Type: news

Adding Niacin to Statins Improves HDL Levels, Not HDL FunctionAdding Niacin to Statins Improves HDL Levels, Not HDL Function
Raising HDL cholesterol levels by adding niacin to statins doesn't improve clinical outcomes, and a new letter in the Journal of the American College of Cardiology suggests why that might be the case. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 26, 2013 Category: Consumer Health News Tags: Cardiology News Source Type: news

Adding Niacin No Help for HDL Function (CME/CE)
(MedPage Today) -- Despite increasing HDL cholesterol levels, the addition of niacin (Niaspan) to statin therapy did not improve the beneficial functions of HDL cholesterol, which could explain the drug's failure to improve clinical outcomes in recent large clinical trials, researchers found. (Source: MedPage Today State Required CME)
Source: MedPage Today State Required CME - August 8, 2013 Category: Consumer Health News Source Type: news

Cardio Notes: Niacin and Stroke Risk
(MedPage Today) -- The correlation of niacin with stroke in the AIM-HIGH trial lost significance when other factors were considered. Also this week, finding vulnerable coronary lesions before they rupture and improving fluoro time. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - July 29, 2013 Category: Cardiology Source Type: news

Potential for new therapeutic options for a diverse array of challenging medical disorders
Researchers have identified a master network of signaling molecules that acts like a "fuse box" to regulate the cellular effects of defective energy flow in mitochondrial respiratory chain diseases - a diverse set of difficult-to-treat genetic-based energy disorders. Using that knowledge, they showed that nicotinic acid, a form of vitamin B3, partially restores normal functioning in cells taken from patients with mitochondrial disease... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 26, 2013 Category: Consumer Health News Tags: Public Health Source Type: news

In A Mouse Model Of Polycystic Kidney Disease, Vitamin B3 Blocks Cyst Formation
Autosomal dominant polycystic kidney disease (ADPKD) is an inherited systemic disorder caused by mutations in PKD1 or PKD2 that predominately affects the kidneys and is characterized by the formation of cysts in the kidneys and other organs. Xiaogang Li and colleagues at the University of Kansas Medical Centr used a mouse model of ADPKD to explore the role of the protein sirtuin 1 in cyst formation. They found that inhibition of sirtuin 1 activity using vitamin B3 can reduced cyst formation in the kidneys of ADPKD mice... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 19, 2013 Category: Consumer Health News Tags: Urology / Nephrology Source Type: news

Increased Niacin (Niaspan) Use in US, CanadaIncreased Niacin (Niaspan) Use in US, Canada
Nearly 700 000 prescriptions per month were written in the US at the end of 2009, an increase of 191% from 2002. In Canada, the use of niacin increased sevenfold, with nearly 14 000 prescriptions written at the end of 2009. Heartwire (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 10, 2013 Category: Consumer Health News Tags: Cardiology News Source Type: news

Niacin use increased nearly 200% over seven-year period
Nearly 700 000 prescriptions per month were written in the US at the end of 2009, an increase of 191% from 2002. In Canada, the use of niacin increased sevenfold, with nearly 14 000 prescriptions written at the end of 2009. (Source: theHeart.org)
Source: theHeart.org - June 10, 2013 Category: Cardiology Source Type: news

HPS2-THRIVE Trial of ER Niacin/LaropiprantHPS2-THRIVE Trial of ER Niacin/Laropiprant
Will extended release niacin be a help or hindrance to adherence and tolerability factors -- when added to lipid lowering regimens? European Heart Journal (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 24, 2013 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

Forum: Niacin and Depression?
Bellaclarke recently posted on the forum: Hi, I've been treated for depression for 12 years with various different antidepressants. At best, they make me feel numb. Also, I experienced side effects from every single type I've taken.  I've reached my breaking point and don't feel like antidepressants are the answer any more.  I've recently done a significant amount of research into high doses of niacin as an alternative to traditional pills. This week I started taking 1000mg of non-flush niacin. Has anyone on here every taken it? What doses did you take? Did it work? Did you take flush or non-flush niacin?......
Source: About.com Depression - April 22, 2013 Category: Psychiatry Source Type: news

Niacin (Niaspan) adverse events in AIM-HIGH, HPS2-THRIVENiacin (Niaspan) adverse events in AIM-HIGH, HPS2-THRIVE
AIM-HIGH researchers have yet to publish a detailed post hoc analysis of adverse events related to niacin therapy, but the investigators do not believe there was a real risk of bleeding or infection observaed with the proprietary extended-release niacin in the trial. However, the HPS2-THRIVE team believes the results of AIM-HIGH support their conclusions about niacin's off-target risks. Heartwire (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 26, 2013 Category: Consumer Health News Tags: Cardiology News Source Type: news