Primary urethral carcinoma: A Surveillance, Epidemiology, and End Results data analysis identifying predictors of cancer-specific survival
Conclusions: Knowledge of patient and tumor characteristics that influences survival is paramount in dictating management. The present study illustrates that age and stage are factors significantly associated with CSS in PUC. (Source: Urology Annals)
Source: Urology Annals - April 9, 2018 Category: Urology & Nephrology Authors: Ilija Aleksic Soroush Rais-Bahrami Michael Daugherty Piyush K Agarwal Srinivas Vourganti Gennady Bratslavsky Source Type: research
Clear cell adenocarcinoma of the urethra with inguinal lymph node metastases: A rare case report and review of literature
Varuna Mallya, Ashwin Mallya, J GayathriJournal of Cancer Research and Therapeutics 2018 14(2):468-470
Urethral cancer is a rare malignancy with urothelial subtype being the most common followed by adenocarcinoma. In women, the usual presentation is urinary retention and hematuria. Clear cell variety of adenocarcinoma is a rarer entity which usually has a better prognosis than other variants. Lymph node metastasis is seen in about 30% of urethral cancers. Histopathological differential diagnosis includes Skene gland carcinoma and nephrogenic adenoma. Herein, we present a 58-year-old female patient who presented...
Source: Journal of Cancer Research and Therapeutics - March 8, 2018 Category: Cancer & Oncology Authors: Varuna Mallya Ashwin Mallya J Gayathri Source Type: research
Skene duct adenocarcinoma in a patient with an elevated serum prostate-specific antigen level: a case report
ConclusionsWe report a very rare case of Skene duct adenocarcinoma in a female patient with serum prostate-specific antigen elevation. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - February 14, 2018 Category: General Medicine Source Type: research
A rare case of primary female urethral adenocarcinoma: Columnar type with colonic adenocarcinoma features.
Abstract
Female urethral carcinoma is extremely rare and accounts for 0.02% of all women's cancers and <1% of cancers in the female genitourinary tract. Adenocarcinoma accounts for only 10% of urethral carcinomas in females. Due to their location, presentation is usually late and tumors are often missed on physical examination. As in this case, nonspecific symptoms in the early stages may delay the diagnosis in most patients. Herein, we present an extremely rare case of the columnar type of primary female urethral adenocarcinoma exhibiting colonic adenocarcinoma features which to the authors' best knowl...
Source: Indian Journal of Pathology and Microbiology - January 1, 2018 Category: Pathology Authors: Gangadhar P, Pai MR, Sandhya I Tags: Indian J Pathol Microbiol Source Type: research
Lower tract neoplasm: Update of imaging evaluation
Publication date: December 2017 Source:European Journal of Radiology, Volume 97 Author(s): Robert Hartman, Akira Kawashima Cancers of the lower urinary tract can arise from the bladder, urachus or urethra. Urothelial carcinoma of the bladder (UCB) is the most common of these. The presentation of bladder, urachal and urethral cancers can differ but many result in hematuria as an initial indication. The diagnosis and staging of these cancers often necessitate radiologic imaging often in the form of cross-section CT urography or MR urography. The following article reviews the specific nature of lower tract cancers and the...
Source: European Journal of Radiology - November 19, 2017 Category: Radiology Source Type: research
Magnetic Resonance Imaging of a Urethral Caruncle and the Pathologic Correlation: A Report of 3 Cases
We present 3 patients with symptomatic urethral caruncles who underwent magnetic resonance imaging preoperatively. (Source: Journal of Computer Assisted Tomography)
Source: Journal of Computer Assisted Tomography - November 1, 2017 Category: Radiology Tags: Abdominal Imaging Source Type: research
The prognostic effect of salvage surgery and radiotherapy in patients with recurrent primary urethral carcinoma.
CONCLUSIONS: In this study, patients who underwent ST for recurrent PUC demonstrated improved OS compared to those who did not receive ST and exhibited similar survival to those who never developed recurrence after primary treatment.
PMID: 29055518 [PubMed - as supplied by publisher] (Source: Urologic Oncology)
Source: Urologic Oncology - October 18, 2017 Category: Urology & Nephrology Authors: Gakis G, Schubert T, Morgan TM, Daneshmand S, Keegan KA, Mischinger J, Clayman RH, Brisuda A, Ali-El-Dein B, Galland S, Gregg J, Balci M, Olugbade K, Rink M, Fritsche HM, Burger M, Babjuk M, Stenzl A, Thalmann GN, Kübler H, Efstathiou JA Tags: Urol Oncol Source Type: research
The prognostic effect of salvage surgery and radiotherapy in patients with recurrent primary urethral carcinoma
To evaluate the impact of salvage therapy (ST) on overall survival (OS) in recurrent primary urethral cancer (PUC). (Source: Urologic Oncology: Seminars and Original Investigations)
Source: Urologic Oncology: Seminars and Original Investigations - October 18, 2017 Category: Urology & Nephrology Authors: Georgios Gakis, Tina Schubert, Todd M. Morgan, Siamak Daneshmand, Kirk A. Keegan, Johannes Mischinger, Rebecca H. Clayman, Antonin Brisuda, Bedeir Ali-El-Dein, Sigolene Galland, Justin Gregg, Melih Balci, Kola Olugbade, Michael Rink, Hans-Martin Fritsche, Tags: Original article Source Type: research
Skene's gland adenocarcinoma with intestinal differentiation: A case report and literature review
We present a case of Skene's gland adenocarcinoma with intestinal differentiation. The patient was a 69‐year‐old Japanese woman who was operated on for a recurrent tumor of the external ostium of the urethra. Histopathologically, the tumor showed glandular and cribriform patterns with a signet‐ring cell component in a mucus lake. Immunohistochemically, the tumor cells were positive for prostate specific acid phosphatase (PSAP), and AMACR, and negative for Nkx3.1 or prostate specific antigen (PSA). Although in situ lesion could not be discovered, positive immunostainings for Nkx3.1, PSAP, and androgen receptor in the ...
Source: Pathology International - September 1, 2017 Category: Pathology Authors: Mariko Muto, Kentaro Inamura, Naoko Ozawa, Takashi Endo, Hitoshi Masuda, Junji Yonese, Yuichi Ishikawa Tags: Case Report Source Type: research
Carcinoma of the Urethra
Primary carcinomas of the urethra are rare and poorly understood lesions, hence their clinical and pathologic spectrum is not completely defined. We analyzed a series of 130 primary urethral tumors and classified 106 of them as primary urethral carcinomas. The age at diagnosis of patients with primary urethral carcinomas ranged from 42 –97years (mean: 69.4yrs.; median: 70yrs). There were 73 males and 33 female patients with a ratio of 2.2:1. In male patients the tumors most frequently developed in the bulbous-membranous segment of the urethra. (Source: Human Pathology)
Source: Human Pathology - August 18, 2017 Category: Pathology Authors: Miao Zhang, Adebowale J. Adeniran, Raghunandan Vikram, Pheroze Tamboli, Curtis Pettaway, Jolanta Bondaruk, Jinsong Liu, Keith Baggerly, Bogdan Czerniak Source Type: research
Contemporary practice patterns and survival outcomes for locally advanced urethral malignancies: A National Cancer Database Analysis
Primary urethral carcinoma (PUC) has an aggressive natural history; however, controversy exists regarding the role of multimodal therapy for its treatment. Our objective was to examine practice patterns and survival outcomes for locally advanced urethral cancers. (Source: Urologic Oncology: Seminars and Original Investigations)
Source: Urologic Oncology: Seminars and Original Investigations - August 10, 2017 Category: Urology & Nephrology Authors: David B. Cahn, Elizabeth Handorf, Benjamin T. Ristau, Daniel M. Geynisman, Jay Simhan, Alexander Kutikov, Richard E. Greenberg, Rosalia Viterbo, David Y.T. Chen, Robert G. Uzzo, Marc C. Smaldone Tags: Original Article Source Type: research
Contemporary practice patterns and survival outcomes for locally advanced urethral malignancies: A National Cancer Database Analysis.
CONCLUSIONS: Despite a survival benefit, most patients with locally advanced PUC do not undergo definitive multimodal therapy. We advocate for a multidisciplinary-based treatment approach for these patients. Future prospective trials of multimodal therapy are crucial.
PMID: 28803701 [PubMed - as supplied by publisher] (Source: Urologic Oncology)
Source: Urologic Oncology - August 10, 2017 Category: Urology & Nephrology Authors: Cahn DB, Handorf E, Ristau BT, Geynisman DM, Simhan J, Kutikov A, Greenberg RE, Viterbo R, Chen DYT, Uzzo RG, Smaldone MC Tags: Urol Oncol Source Type: research
Sex-related differences in clinicopathological features and survival of patients with primary urethral carcinoma: a population-based study
(Source: OncoTargets and Therapy)
Source: OncoTargets and Therapy - July 10, 2017 Category: Cancer & Oncology Tags: OncoTargets and Therapy Source Type: research
Priapism with penile gangrene: An unusual presentation of multiple myeloma
We present a 44-year-old patient of multiple myeloma presenting with ischemic priapism and penile gangrene requiring partial penectomy. (Source: Indian Journal of Urology)
Source: Indian Journal of Urology - June 30, 2017 Category: Urology & Nephrology Authors: Vikas Kumar Panwar Ravimohan S Mavuduru Sudheer Kumar Devana Kim Vaiphei Girdhar Singh Bora Source Type: research
Syndrome of Inappropriate Secretion of Antidiuretic Hormone Caused by Carboplatin After Switching from Cisplatin in a Metastatic Urethral Cancer Patient
In this report, we describe a 66-year-old woman who was diagnosed as mPUC with, CDDP-induced SIADH. After switching her to CBDCA and careful managing her sodium balance, three courses of the chemotherapy regimen were completed. (Source: Urology Case Reports)
Source: Urology Case Reports - February 28, 2017 Category: Urology & Nephrology Source Type: research
