Penile-preserving surgery for primary urothelial carcinoma of male urethra
We report an 84-year-old male patient, with a history of chronic hepatitis C, hypertension, and transient ischemic accident, who presented with dysuria and acute urinary retention. The intravenous urography showed mild prostatic enlargement, but no stone or filling defect was noted in the upper urinary tract. On urethrocystoscopy, multiple papillary tumors were found at the pendulous urethra, and the pathology of biopsy confirmed urothelial carcinoma. The patient was admitted, and electroresection with fulguration of urethral tumors was performed owing to the patient's old age and poor performance status. Intraurethral and...
Source: Urological Science - April 11, 2015 Category: Urology & Nephrology Source Type: research
Mp10-16 substitution urethroplasty for treatment of distal urethral carcinoma and carcinoma in situ
Urethral cancers are rare, comprising (Source: The Journal of Urology)
Source: The Journal of Urology - April 1, 2015 Category: Urology & Nephrology Authors: Meghana Kulkarni, Mahua Sahu, Alberto Coscione, Davendra Sharma, Benjamin Ayres, Nicholas Watkin Tags: Sexual Function/Dysfunction/Andrology: Penis/Testis/Urethra: Malignant Disease Source Type: research
Mp65-09 impact of perioperative chemotherapy on survival in patients with advanced primary urethral cancer: results of the international collaboration on primary urethral carcinoma
Primary urethral carcinoma (PUC) is an uncommon but potentially lethal genitourinary malignancy that meets the definition of a “rare cancer,” accounting for well under 1% of all malignancies. In Western countries, the incidence is reported to range between 0.6-1.6 per 1.000.000. Given the rarity of this cancer, there remain critical gaps in our understanding of the optimal management of patients with PUC. In particular, there are no reports we are aware of addressing the timing of perioperative chemotherapy in patients with clinically advanced PUC. (Source: The Journal of Urology)
Source: The Journal of Urology - April 1, 2015 Category: Urology & Nephrology Authors: Georgios Gakis, Todd Morgan, Siamak Daneshmand, Kirk Keegan, Harras Zaid, Jan Hrbacek, Bedeir Ali-El-Dein, Rebecca Clayman, Tilman Todenhöfer, Sigolene Galland, Kola Olugbade Jr., Michael Rink, Hans-Martin Fritsche, Maximillian Burger, Sam Chang, Marko B Tags: Bladder Cancer: Invasive III Source Type: research
Lymphadenectomy for testicular, penile, upper tract urothelial and urethral cancers
Purpose of review: The lymph node dissection (LND) is an integral component of many oncologic surgeries. Better understanding of each cancer's behaviour and improvements in surgical techniques necessitate a critical analysis of lymph node disease and the optimal LND template. This review will focus on updates in managing lymph node disease in testicular, penile, upper tract urothelial and urethral cancer.
Recent findings: For testicular and penile cancer, advances have focused on reducing the morbidity associated with the standard templates of dissection while maintaining oncologic efficacy. For upper tract urothelial carc...
Source: Current Opinion in Urology - February 2, 2015 Category: Urology & Nephrology Tags: ORGAN SPARING SURGERY IN UROLOGY: Edited by Inderbir S. Gill Source Type: research
Pneumomediastinum as a complication of SABR for lung metastases
Conclusion:
Radiation oncologist should be aware of the potential risk of severe lung toxicity caused by SABR in patients with ILD, especially when chemotherapy-induced pulmonary toxicity is administered in a short time interval. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - January 23, 2015 Category: Epidemiology Authors: María Rodríguez-RuizEstefanía ArévaloIgnacio Gil-BazoAlicia GarcíaGerman ValtueñaMarta Moreno-JiménezLeire Arbea-MorenoJavier Mendioroz Source Type: research
Eighteen years experience of granulocyte donations—acceptable donor safety?
Conclusion: No serious short‐term AE were observed. Due to the variability of diagnoses among excluded/deceased donors, we propose that it is less likely that granulocyte donations have a causative impact on these donors' exclusion or death. J. Clin. Apheresis, 2014. © 2014 Wiley Periodicals, Inc. (Source: Journal of Clinical Apheresis)
Source: Journal of Clinical Apheresis - December 26, 2014 Category: Hematology Authors: Ulla Axdorph Nygell, Agneta Sollén‐Nilsson, Joachim Lundahl Tags: Research Article Source Type: research
Clinicopathological features of carcinoma of the distal penile urethra
Distal urethral carcinomas are very rare and are similar in their pathology and behaviour to tumours of the glans penis and foreskin. Similarly they are associated with Penile Intraepithelial Neoplasia (PeIN) of both differentiated and undifferentiated types. Current management is mainly surgical, but increasingly involves specialist penile preserving techniques. Handling and dissection of the specimens is broadly the same as other primary penile tumours.The prognosis of distal urethral lesions is believed to be worse than penile tumours and better than prostatic urethral tumours but the evidence is sparse. (Source: Semina...
Source: Seminars in Diagnostic Pathology - December 24, 2014 Category: Pathology Authors: Catherine M. Corbishley, Ramzi M. Rajab, Nicholas A. Watkin Source Type: research
Transurethral holmium laser vaporization to the urethral tumour through a ureteroscope.
We present 2 cases of urethral cancers: one is recurrent bladder transitional cell carcinoma accompanied by urethral metastatic carcinoma located on the right side of verumontanum, and the other is primary bladder and metastatic urethral adenocarcinoma. The urethral tumour was treated by transurethral holmium laser vaporization to the urethral tumour through a ureteroscope and the bladder tumour was treated with transurethral resection and degeneration of the bladder tumour (TURD-Bt). After the second or third therapy, patients were free of urethral or bladder tumour recurrence; they also did not experience urethral strict...
Source: Canadian Urological Association Journal - November 1, 2014 Category: Urology & Nephrology Authors: Li A, Fang W, Zuo X, Zhang F, Li W, Lu H, Liu S, Wang H, Zhang B Tags: Can Urol Assoc J Source Type: research
Occult distal urethral carcinoma presenting as metastatic carcinoma in the inguinal lymph nodes
Scandinavian Journal of Urology, Ahead of Print. (Source: Scandinavian Journal of Urology)
Source: Scandinavian Journal of Urology - October 14, 2014 Category: Urology & Nephrology Tags: article Source Type: research
[Penis-preserving surgery in patients with primary penile urethral cancer.]
CONCLUSION: Primary penile urethral cancer can be treated by a penis-preserving operation. Close follow-up is essential because recurrence can arise despite an initial R0 resection.
PMID: 25272986 [PubMed - as supplied by publisher] (Source: Der Urologe. Ausg. A)
Source: Der Urologe. Ausg. A - October 3, 2014 Category: Urology & Nephrology Authors: Maek M Tags: Urologe A Source Type: research
Re: Retrospective Analysis of Survival Outcomes and the Role of Cisplatin-Based Chemotherapy in Patients with Urethral Carcinomas Referred to Medical Oncologists
F. Dayyani, C. A. Pettaway, A. M. Kamat, M. F. Munsell, K. Sircar and L. C. Pagliaro (Source: The Journal of Urology)
Source: The Journal of Urology - September 18, 2014 Category: Urology & Nephrology Authors: David P. Wood Tags: Urological Survey Source Type: research
[Organ and function preservation in urethral cancer.]
Abstract
Primary urethral carcinomas are rare tumors that can occur both in men and women. Histological patterns of these tumors are mixed, urothelial tumors occur as well as squamous cell tumors or adenocarcinomas.There are different clinical factors that define clinical prognosis, and the 1- and 5-year cancer-free survival is 75% and 54%. Therapy of locally limited disease is surgical resection, and organ-preserving treatment is possible if negative frozen sections prove complete surgical resection. However, in men a perineal urethrostomy might be necessary, and in women there is a high risk of urinary i...
Source: Der Urologe. Ausg. A - August 13, 2014 Category: Urology & Nephrology Authors: Tritschler S, Lellig K, Roosen A, Horng A, Stief C Tags: Urologe A Source Type: research
Combined Chemoradiation as Primary Treatment for Invasive Male Urethral Cancer
To evaluate the efficacy and intermediate term outcomes of a combined chemoradiation protocol for the treatment of primary invasive carcinoma of the male urethra. (Source: The Journal of Urology)
Source: The Journal of Urology - July 31, 2014 Category: Urology & Nephrology Authors: Marissa Kent, Leonard Zinman, Lyubov Girshovich, Jacob Sands, Alex Vanni Source Type: research
Urethral squamous cell papilloma: Case report and literature review.
We present a case of a urethral squamous papilloma at the urethral meatus in a premenopausal woman causing significant symptoms.
PMID: 24940467 [PubMed] (Source: Canadian Urological Association Journal)
Source: Canadian Urological Association Journal - May 1, 2014 Category: Urology & Nephrology Authors: Gustafson P, Fenster HN, So AI Tags: Can Urol Assoc J Source Type: research
