Clinicopathological features of carcinoma of the distal penile urethra

Distal urethral carcinomas are very rare and are similar in their pathology and behaviour to tumours of the glans penis and foreskin. Similarly they are associated with Penile Intraepithelial Neoplasia (PeIN) of both differentiated and undifferentiated types. Current management is mainly surgical, but increasingly involves specialist penile preserving techniques. Handling and dissection of the specimens is broadly the same as other primary penile tumours.The prognosis of distal urethral lesions is believed to be worse than penile tumours and better than prostatic urethral tumours but the evidence is sparse.
Source: Seminars in Diagnostic Pathology - Category: Pathology Authors: Source Type: research