Recent progress in follicular lymphoma in Japan and characteristics of the duodenal type
The incidence of lymphoma has rapidly increased over the last 40 years in Japan, following a trend that is very similar to that of breast cancer. In particular, the relative frequency of follicular lymphoma (FL) has reached that in Western countries. Given its indolence, a “watch‐and‐wait” approach is often applied to FL patients. We have shown that FL is often detected in the second portion of the duodenum and has a distinct follicular dendritic cell distribution and heavy chain variable usage similar to mucosa‐associated lymphoid tissue (MALT) lymphoma. Al though the t(14;18)(q32;q21) frequency is the same as i...
Source: Pathology International - November 20, 2018 Category: Pathology Authors: Tadashi Yoshino, Katsuyoshi Takata, Takehiro Tanaka, Yasuharu Sato, Akira Tari, Hiroyuki Okada Tags: Review Article Source Type: research

Epstein ‐Barr virus (EBV)‐positive diffuse large B‐cell lymphoma arising in patient with a history of EBV‐positive mucocutaneous ulcer and EBV‐positive nodal polymorphous B‐lymphoproliferative disorder
Elderly patients with Epstein ‐Barr virus (EBV) infection are at increased risk for developing B‐cell lymphoproliferative disorder (B‐LPD) due to immunosenescence. Here, we describe a case of a 75‐year‐old man who developed an EBV‐positive (EBV+) mucocutaneous ulcer (EBVMCU) in the gingiva with spontaneous regression . Eighteen months after regression, he had a cervical lymph node enlargement that was diagnosed as EBV+ nodal polymorphous B‐LPD, Ann Arbor stage IA. Clinicians decided to observe his clinical course without any treatment. Fourteen months later, the patient developed EBV‐positive diffuse large ...
Source: Pathology International - November 19, 2018 Category: Pathology Authors: Teerada Daroontum, Kei Kohno, Yoko Inaguma, Akinao Okamoto, Masataka Okamoto, Yoshihiro Kimura, Masato Nagahama, Ayako Sakakibara, Akira Satou, Shigeo Nakamura Tags: Case Report Source Type: research

Histopathological characterization of the neuroglial tissue in ovarian teratoma associated with anti ‐N‐methyl‐D‐aspartate (NMDA) receptor encephalitis
Anti ‐N‐methyl‐D‐aspartate (NMDA) receptor encephalitis is a rare but occasionally fatal limbic encephalitis that may be accompanied by ovarian teratoma. Since the neuroglial tissue within the teratoma may be involved in the pathogenesis of this encephalitis, we attempted morphological and immuno histochemical characterization of the neuroglial tissue in four cases of ovarian teratoma associated with anti‐NMDA receptor encephalitis and 12 control cases, i.e., six consecutive cases of immature teratoma and six cases of mature teratoma with an abundant neuronal component, focusing mainly on NMDA receptor‐expressi...
Source: Pathology International - November 14, 2018 Category: Pathology Authors: Yoshiki Iemura, Yosuke Yamada, Masahiro Hirata, Tatsuki R Kataoka, Sachiko Minamiguchi, Hinonori Haga Tags: Original Article Source Type: research

“Integrated diagnosis” of pilocytic astrocytoma: Molecular diagnostic procedure for an unusual case
A 24 year ‐old female presented with a mass lesion in the right temporal lobe. This case was difficult to diagnose using histological and immunological methods and therefore molecular analyses were applied to provide a definitive diagnosis. The tumor was well‐demarcated, partially cystic, and irregularly‐ enhanced on gadolinium‐enhanced T1‐weighted magnetic resonance images. Pathologically, a large part of the tumor consisted of cells with fine cytoplasmic processes on a myxoid and mucinous background. Cells formed a microcystic structure around the mucinous tissue. Numerous eosinophilic granular bodies, but not ...
Source: Pathology International - November 12, 2018 Category: Pathology Authors: Yusuke Ishida, Masumi Tsuda, Yutaka Sawamura, Kyoko Fujii, Hiroshi Murai, Naruyoshi Horiuchi, Yasuko Orba, Hirofumi Sawa, William W Hall, Kazuo Nagashima, Shinya Tanaka Tags: Case Report Source Type: research

Adenosquamous carcinoma of the papilla of Vater: A phenotypic heterogeneity characterized by a common molecular landscape
Pathology International, EarlyView. (Source: Pathology International)
Source: Pathology International - November 12, 2018 Category: Pathology Authors: Anna Caterina Milanetto, Li ço Valbona, Rita Alaggio, Giada Munari, Sergio Pedrazzoli, Matteo Fassan, Claudio Pasquali Tags: Letter to the Editor Source Type: research

Recurrent monomorphic epitheliotropic intestinal T ‐cell lymphoma with aberrant CD20 expression: An implication for anti‐CD20 (rituximab) antibody therapy?
Pathology International, EarlyView. (Source: Pathology International)
Source: Pathology International - November 6, 2018 Category: Pathology Authors: Pi ‐Han Liao, Shih‐Cheng Chou, Wan‐Ting Huang, Ying‐Zhen Su, Ming‐Chung Wang, Shih‐Sung Chuang Tags: Letter to the Editor Source Type: research

Issue Information
Pathology International,Volume 68, Issue 11, Page i-iv, November 2018. (Source: Pathology International)
Source: Pathology International - November 3, 2018 Category: Pathology Source Type: research

Abstracts of A ‐ Presentation by the winners of The Japanese Society of Pathology; Pathology Research Award in 2018 (in program order)
Pathology International,Volume 68, Issue 11, Page 636-639, November 2018. (Source: Pathology International)
Source: Pathology International - November 3, 2018 Category: Pathology Source Type: research

Aggressive cribriform ‐morular variant of papillary thyroid carcinoma: Report of an unusual case with pulmonary metastasis displaying poorly differentiated features
Pathology International, EarlyView. (Source: Pathology International)
Source: Pathology International - October 30, 2018 Category: Pathology Authors: Hiromi Tsuji, Hironao Yasuoka, Yasushi Nakamura, Mitsuyoshi Hirokawa, Takashi Hiroshima, Yasushi Sakamaki, Akira Miyauchi, Masahiko Tsujimoto Source Type: research

NUT Carcinoma: Clinicopathologic features, pathogenesis, and treatment
Pathology International, EarlyView. (Source: Pathology International)
Source: Pathology International - October 26, 2018 Category: Pathology Authors: Christopher A. French Source Type: research

Diagnostic value of HBME ‐1, CK19, Galectin 3, and CD56 in the subtypes of follicular variant of papillary thyroid carcinoma
Pathology International, EarlyView. (Source: Pathology International)
Source: Pathology International - October 23, 2018 Category: Pathology Authors: Haeyon Cho, Ji ‐Ye Kim, Young Lyun Oh Source Type: research

High expression of ovarian cancer immunoreactive antigen domain containing 2 (OCIAD2) is associated with poor prognosis in lung adenocarcinoma
Pathology International, EarlyView. (Source: Pathology International)
Source: Pathology International - October 15, 2018 Category: Pathology Authors: Mai Sakashita, Shingo Sakashita, Yoshihiko Murata, Aya Shiba ‐Ishii, Yunjung Kim, Ryota Matsuoka, Noriyuki Nakano, Yukio Sato, Masayuki Noguchi Source Type: research

A case of combined small cell lung carcinoma with unique morphology: Investigation of tumorigenesis
Pathology International, EarlyView. (Source: Pathology International)
Source: Pathology International - October 12, 2018 Category: Pathology Authors: Miki Asahina, Yuki Fukumura, Osman Mamat, Tsuyoshi Saito, Takuo Hayashi, Toshimasa Uekusa, Kenji Suzuki, Takashi Yao Source Type: research

Issue Information
Pathology International,Volume 68, Issue 10, Page i-iv, October 2018. (Source: Pathology International)
Source: Pathology International - October 5, 2018 Category: Pathology Source Type: research

Synchronous case of follicular lymphoma and Langerhans cell sarcoma in the same lymph node
Pathology International, EarlyView. (Source: Pathology International)
Source: Pathology International - September 26, 2018 Category: Pathology Authors: Joji Shimono, Hiroaki Miyoshi, Fumiko Arakawa, Hideyuki Abe, Takuto Miyagishima, Jun Akiba, Takanori Teshima, Koichi Ohshima Source Type: research