High carriage of plasmid-mediated quinolone resistance (PMQR) genes by ESBL-producing and fluoroquinolone-resistant Escherichia coli recovered from animal waste dumps
CONCLUSIONS: This study showed that animal wastes disposed indiscriminately into dumps could be a budding 'hotspot' for multidrug resistant, ESBL-producing and fluoroquinolone-resistant E. coli carrying multiple genes encoding resistance to fluoroquinolone antibiotics.PMID:38491992 | DOI:10.1007/s11033-024-09228-8 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - March 16, 2024 Category: Molecular Biology Authors: Elizabeth Omokoshi Joel Olabisi Comfort Akinlabi Adedolapo Victoria Olaposi Temitayo Omotunde Olowomofe Abimbola Olumide Adekanmbi Source Type: research
High carriage of plasmid-mediated quinolone resistance (PMQR) genes by ESBL-producing and fluoroquinolone-resistant Escherichia coli recovered from animal waste dumps
CONCLUSIONS: This study showed that animal wastes disposed indiscriminately into dumps could be a budding 'hotspot' for multidrug resistant, ESBL-producing and fluoroquinolone-resistant E. coli carrying multiple genes encoding resistance to fluoroquinolone antibiotics.PMID:38491992 | DOI:10.1007/s11033-024-09228-8 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - March 16, 2024 Category: Molecular Biology Authors: Elizabeth Omokoshi Joel Olabisi Comfort Akinlabi Adedolapo Victoria Olaposi Temitayo Omotunde Olowomofe Abimbola Olumide Adekanmbi Source Type: research
Exploring variations in recommended first ‐choice therapy for complicated urinary tract infections in males: Insights from outpatient settings across age, race, and ethnicity
ConclusionsNearly half of the patients included in this study did not receive recommended first-choice therapies; however, racial and ethnic disparities were not identified. Underutilization of recommended first-choice antibiotic therapy in complicated UTIs continues to be an area of focus for antimicrobial stewardship programs. (Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy)
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - March 14, 2024 Category: Drugs & Pharmacology Authors: Kathryn Sine,
Thomas Lavoie,
Aisling R. Caffrey,
Vrishali V. Lopes,
David Dosa,
Kerry L. LaPlante,
Haley J. Appaneal Tags: RESEARCH ARTICLE Source Type: research
Use of sawdust for production of ligninolytic enzymes by white-rot fungi and pharmaceutical removal
Bioprocess Biosyst Eng. 2024 Mar 14. doi: 10.1007/s00449-024-02976-8. Online ahead of print.ABSTRACTUse of white-rot fungi for enzyme-based bioremediation of wastewater is of high interest. These fungi produce considerable amounts of extracellular ligninolytic enzymes during solid-state fermentation on lignocellulosic materials such as straw and sawdust. We used pure sawdust colonized by Pleurotus ostreatus, Trametes versicolor, and Ganoderma lucidum for extraction of ligninolytic enzymes in aqueous suspension. Crude enzyme suspensions of the three fungi, with laccase activity range 12-43 U/L and manganese peroxidase activ...
Source: Bioprocess and Biosystems Engineering - March 14, 2024 Category: Biomedical Engineering Authors: M Hultberg O Golovko Source Type: research
Use of sawdust for production of ligninolytic enzymes by white-rot fungi and pharmaceutical removal
Bioprocess Biosyst Eng. 2024 Mar 14. doi: 10.1007/s00449-024-02976-8. Online ahead of print.ABSTRACTUse of white-rot fungi for enzyme-based bioremediation of wastewater is of high interest. These fungi produce considerable amounts of extracellular ligninolytic enzymes during solid-state fermentation on lignocellulosic materials such as straw and sawdust. We used pure sawdust colonized by Pleurotus ostreatus, Trametes versicolor, and Ganoderma lucidum for extraction of ligninolytic enzymes in aqueous suspension. Crude enzyme suspensions of the three fungi, with laccase activity range 12-43 U/L and manganese peroxidase activ...
Source: Bioprocess and Biosystems Engineering - March 14, 2024 Category: Biomedical Engineering Authors: M Hultberg O Golovko Source Type: research
Molecular typing of clinical multidrug-resistant Klebsiella pneumoniae isolates
CONCLUSION: Both PCR-typing methods with phenotypic patterns can be useful for the epidemiological typing of K. pneumoniae isolates with the highest performance in discriminating isolates.PMID:38478145 | DOI:10.1007/s11033-024-09278-y (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - March 13, 2024 Category: Molecular Biology Authors: Mehdi Kashefieh Habib Zeighami Hossein Samadi Kafil Pourya Gholizadeh Javid Sadeghi Mohammad Hossein Soroush Barhaghi Hamed Ebrahimzadeh Leylabadlo Reza Ghotaslou Source Type: research
Prevalence and molecular characterization of multi-resistant < em > Escherichia coli < /em > isolates from clinical bovine mastitis in China
This study aimed to investigate the occurrence and molecular characteristics of resistance determinants in E. coli strains (n = 105) obtained from lactating cows with clinical bovine mastitis (CBM) in China. A total of 220 cows with clinical mastitis, which has swollen mammary udder with reduced and red or gangrenous milk, were selected from 5000 cows. The results showed 94.3% of the isolates were recognized as multidrug resistant. The isolates (30.5%) were positive for the class I integrase gene along with seven gene cassettes that were accountable for resistance to trimethoprim resistance (dfrA17, dfr2d and dfrA1), amino...
Source: Animal Biotechnology - March 13, 2024 Category: Biotechnology Authors: Hongxia Zhao Hailan Ma Chen Song Shuting Fan Hongliang Fan Weiguang Zhou Jinshan Cao Source Type: research
Prevalence and molecular characterization of multi-resistant < em > Escherichia coli < /em > isolates from clinical bovine mastitis in China
This study aimed to investigate the occurrence and molecular characteristics of resistance determinants in E. coli strains (n = 105) obtained from lactating cows with clinical bovine mastitis (CBM) in China. A total of 220 cows with clinical mastitis, which has swollen mammary udder with reduced and red or gangrenous milk, were selected from 5000 cows. The results showed 94.3% of the isolates were recognized as multidrug resistant. The isolates (30.5%) were positive for the class I integrase gene along with seven gene cassettes that were accountable for resistance to trimethoprim resistance (dfrA17, dfr2d and dfrA1), amino...
Source: Animal Biotechnology - March 13, 2024 Category: Biotechnology Authors: Hongxia Zhao Hailan Ma Chen Song Shuting Fan Hongliang Fan Weiguang Zhou Jinshan Cao Source Type: research
Molecular typing of clinical multidrug-resistant Klebsiella pneumoniae isolates
CONCLUSION: Both PCR-typing methods with phenotypic patterns can be useful for the epidemiological typing of K. pneumoniae isolates with the highest performance in discriminating isolates.PMID:38478145 | DOI:10.1007/s11033-024-09278-y (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - March 13, 2024 Category: Molecular Biology Authors: Mehdi Kashefieh Habib Zeighami Hossein Samadi Kafil Pourya Gholizadeh Javid Sadeghi Mohammad Hossein Soroush Barhaghi Hamed Ebrahimzadeh Leylabadlo Reza Ghotaslou Source Type: research
Prevalence and molecular characterization of multi-resistant < em > Escherichia coli < /em > isolates from clinical bovine mastitis in China
This study aimed to investigate the occurrence and molecular characteristics of resistance determinants in E. coli strains (n = 105) obtained from lactating cows with clinical bovine mastitis (CBM) in China. A total of 220 cows with clinical mastitis, which has swollen mammary udder with reduced and red or gangrenous milk, were selected from 5000 cows. The results showed 94.3% of the isolates were recognized as multidrug resistant. The isolates (30.5%) were positive for the class I integrase gene along with seven gene cassettes that were accountable for resistance to trimethoprim resistance (dfrA17, dfr2d and dfrA1), amino...
Source: Animal Biotechnology - March 13, 2024 Category: Biotechnology Authors: Hongxia Zhao Hailan Ma Chen Song Shuting Fan Hongliang Fan Weiguang Zhou Jinshan Cao Source Type: research
Prevalence and molecular characterization of multi-resistant < em > Escherichia coli < /em > isolates from clinical bovine mastitis in China
This study aimed to investigate the occurrence and molecular characteristics of resistance determinants in E. coli strains (n = 105) obtained from lactating cows with clinical bovine mastitis (CBM) in China. A total of 220 cows with clinical mastitis, which has swollen mammary udder with reduced and red or gangrenous milk, were selected from 5000 cows. The results showed 94.3% of the isolates were recognized as multidrug resistant. The isolates (30.5%) were positive for the class I integrase gene along with seven gene cassettes that were accountable for resistance to trimethoprim resistance (dfrA17, dfr2d and dfrA1), amino...
Source: Animal Biotechnology - March 13, 2024 Category: Biotechnology Authors: Hongxia Zhao Hailan Ma Chen Song Shuting Fan Hongliang Fan Weiguang Zhou Jinshan Cao Source Type: research
Serotype distribution and antimicrobial resistance of pediatric Streptococcus pneumoniae isolated from inpatients and outpatients at Beijing Children's Hospital
CONCLUSIONS: Pneumococcal vaccine-related serotypes are prevalent among both inpatients and outpatients, especially among inpatients, who exhibit more severe antibiotic resistance. Therefore, universal immunization with PCV13 would decrease the hospitalization rate due to S. pneumoniae and the antibiotic resistance rate of S. pneumoniae.PMID:38471654 | DOI:10.1016/j.bjid.2024.103734 (Source: Braz J Infect Dis)
Source: Braz J Infect Dis - March 12, 2024 Category: Infectious Diseases Authors: Shuang Lyu Wei Shi Fang Dong Bao Ping Xu Gang Liu Quan Wang Kai Hu Yao Yong Hong Yang Source Type: research
Metagenomics insights into microbiome and antibiotic resistance genes from free living amoeba in chlorinated wastewater effluents
In this study we comprehensively analyzed the microbiome, antibiotic resistome and virulence factors (VFs) within FLA isolated from final treated effluents of two wastewater treatment plants (WWTPs) using shotgun metagenomics. Acanthamoeba has been identified as the most common FLA, followed by Entamoeba. The bacterial diversity showed no significant difference (p > 0.05) in FLA microbiomes obtained from the two WWTPs. At phylum level, the most dominant taxa were Proteobacteria, followed by Firmicutes and Actinobacteria. The most abundant genera identified were Enterobacter followed by Citrobacter, Paenibacillus, and Cu...
Source: International Journal of Hygiene and Environmental health - March 12, 2024 Category: Environmental Health Authors: Thobela Conco-Biyela Muneer Ahmad Malla Oluyemi Olatunji Awolusi Mushal Allam Arshad Ismail Thor A Stenstr öm Faizal Bux Sheena Kumari Source Type: research
Serotype distribution and antimicrobial resistance of pediatric Streptococcus pneumoniae isolated from inpatients and outpatients at Beijing Children's Hospital
CONCLUSIONS: Pneumococcal vaccine-related serotypes are prevalent among both inpatients and outpatients, especially among inpatients, who exhibit more severe antibiotic resistance. Therefore, universal immunization with PCV13 would decrease the hospitalization rate due to S. pneumoniae and the antibiotic resistance rate of S. pneumoniae.PMID:38471654 | DOI:10.1016/j.bjid.2024.103734 (Source: Braz J Infect Dis)
Source: Braz J Infect Dis - March 12, 2024 Category: Infectious Diseases Authors: Shuang Lyu Wei Shi Fang Dong Bao Ping Xu Gang Liu Quan Wang Kai Hu Yao Yong Hong Yang Source Type: research
