Histidine-Rich Glycoprotein Modulates the Toxic Effects of High-Dose Polyphosphate in Mice
CONCLUSIONS: High-dose intravenous polyP is cardiotoxic in mice, and HRG modulates this effect.PMID:38752349 | DOI:10.1161/ATVBAHA.124.320899 (Source: Atherosclerosis)
Source: Atherosclerosis - May 16, 2024 Category: Cardiology Authors: Rida A Malik Ji Zhou James C Fredenburgh Jeff Crosby Alexey S Revenko Jeff S Healey Jeffrey I Weitz Source Type: research
Mitral Valve Replacement in Infants and Children: Five Year Outcomes of the HALO Clinical Trial
CONCLUSIONS: In small children with severe mitral valve disease requiring MVR, the 15mm SJM MHV provides satisfactory hemodynamics. Mortality and complications in these patients are not trivial. Low molecular weight heparin likely should be avoided as primary anticoagulation. Eventual valve replacement is inevitable.PMID:38750684 | DOI:10.1016/j.athoracsur.2024.04.025 (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - May 16, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Fawwaz R Shaw Brian Kogon Jonathan Chen Max B Mitchell Charles Fraser Kirk Kanter Source Type: research
Aspirin and prevention of the recurrence of venous thromboembolism
Ann Cardiol Angeiol (Paris). 2024 May 15;73(3):101761. doi: 10.1016/j.ancard.2024.101761. Online ahead of print.ABSTRACTAfter a first episode of unprovoked vein thrombosis, the risk of recurrence persists for many years. Long term of anticoagulant therapy prevents the recurrence of vein thrombosis but is associated with a major risk of bleeding. As platelets play a role in the initiation and propagation of venous thromboembolism as well, antiplatelet agents, may play a role in the treatment and prevention of this disease. This review summarizes available evidence on effect of aspirin in the prevention of recurrent deep vei...
Source: Annales de Cardiologie et d'Angeiologie - May 16, 2024 Category: Cardiology Authors: Raida Ben Salah Abir Derbel Imen Chabchoub Faten Frikha Sameh Marzouk Zouhir Bahloul Source Type: research
A clinical comparative study of dual LVIS devices and single flow diversion stenting for the treatment of unruptured V3-V4 vertebral artery dissection
CONCLUSION: Both methods could effectively treat unruptured VAD in V3-V4 segments. Nevertheless, simple FD implantation is relatively easier to perform and involves lower radiation exposure.PMID:38751187 | DOI:10.1177/15910199241254864 (Source: Interventional Neuroradiology)
Source: Interventional Neuroradiology - May 16, 2024 Category: Radiology Authors: Shuhai Long Shuailong Shi Zhike Zhang Qi Tian Zhuangzhuang Wei Ji Ma Ye Wang Jie Yang Xinwei Han Tengfei Li Source Type: research
Experimental comparison of first-pass effect between direct thromboaspiration and combined thrombectomy in the setting of distal basilar occlusion
CONCLUSIONS: In the context of distal basilar occlusion, our in-vitro results showed that higher first-pass effect rates were achieved with direct thromboaspiration compared to combined thrombectomy in all types of thrombus analogs.PMID:38751100 | DOI:10.1177/15910199241254412 (Source: Interventional Neuroradiology)
Source: Interventional Neuroradiology - May 16, 2024 Category: Radiology Authors: Reza Seiffert Olivier Brina Philippe Reymond Jeremy Hofmeister Gianmarco Bernava Andrea Rosi Lars Michels Zsolt Kulcsar Karl-Olof Lovblad Paolo Machi Source Type: research
Comparative genomics of two Asian medicinal leeches Hirudo nipponia and Hirudo tianjinensis: With emphasis on antithrombotic genes and their corresponding proteins
Int J Biol Macromol. 2024 May 15;270(Pt 1):132278. doi: 10.1016/j.ijbiomac.2024.132278. Online ahead of print.ABSTRACTLeeches secrete various biologically active substances which have important medical and pharmaceutical values in antithrombotic treatments. Here, we provide a high quality genome of two Asian medicinal leeches Hirudo nipponia and Hirudo tianjinensis, based on which, we identified 22 antithrombotic gene families, including fourteen coagulation inhibitors, four platelet aggregation inhibitors, three fibrinolysis enhancers, and one tissue penetration enhancer. The total numbers of antithrombotic genes were sim...
Source: International Journal of Biological Macromolecules - May 16, 2024 Category: Biochemistry Authors: Fang Zhao Zuhao Huang Bo He Kaiqing Liu Junyu Li Zichao Liu Gonghua Lin Source Type: research
Venous thromboembolism among Asian populations with localized colorectal cancer undergoing curative resection: is pharmacological thromboprophylaxis required? A systematic review and meta-analysis
CONCLUSION: The benefit of PTP in reducing VTE incidence among Asian patients undergoing curative resection for localized colorectal cancer has not been clearly established. The decision to administer PTP should be evaluated on a case-bycase basis and with consideration of associated bleeding risks.PMID:38752323 | DOI:10.3393/ac.2022.01046.0149 (Source: Annals of Coloproctology)
Source: Annals of Coloproctology - May 16, 2024 Category: Gastroenterology Authors: Shih Jia Janice Tan Emile Kwong-Wei Tan Yvonne Ying Ru Ng Rehena Sultana John Carson Allen Isaac Seow-En Ronnie Mathew Aik Yong Chok Source Type: research
Further Research Is Necessary to Demonstrate Potential Advantages of Ultrasound Assisted Catheter Directed Thrombolysis in The Management of Proximal Deep Vein Thrombosis
Eur J Vasc Endovasc Surg. 2024 May 14:S1078-5884(24)00395-2. doi: 10.1016/j.ejvs.2024.05.017. Online ahead of print.NO ABSTRACTPMID:38754726 | DOI:10.1016/j.ejvs.2024.05.017 (Source: PubMed: Eur J Vasc Endovasc ...)
Source: PubMed: Eur J Vasc Endovasc ... - May 16, 2024 Category: Surgery Authors: Mohammed Ashrafi Stavros A Antoniou George A Antoniou Source Type: research
Association of Aortic Stiffness and Pressure Pulsatility With Noninvasive Estimates of Hepatic Steatosis and Fibrosis: The Framingham Heart Study
CONCLUSIONS: Elevated aortic stiffness and pressure pulsatility may contribute to hepatic steatosis and fibrosis.PMID:38752348 | DOI:10.1161/ATVBAHA.123.320553 (Source: Arteriosclerosis, Thrombosis and Vascular Biology)
Source: Arteriosclerosis, Thrombosis and Vascular Biology - May 16, 2024 Category: Cardiology Authors: Leroy L Cooper Brenton R Prescott Vanessa Xanthakis Emelia J Benjamin Ramachandran S Vasan Naomi M Hamburg Michelle T Long Gary F Mitchell Source Type: research
Histidine-Rich Glycoprotein Modulates the Toxic Effects of High-Dose Polyphosphate in Mice
CONCLUSIONS: High-dose intravenous polyP is cardiotoxic in mice, and HRG modulates this effect.PMID:38752349 | DOI:10.1161/ATVBAHA.124.320899 (Source: Arteriosclerosis, Thrombosis and Vascular Biology)
Source: Arteriosclerosis, Thrombosis and Vascular Biology - May 16, 2024 Category: Cardiology Authors: Rida A Malik Ji Zhou James C Fredenburgh Jeff Crosby Alexey S Revenko Jeff S Healey Jeffrey I Weitz Source Type: research
De Novo Elastin Assembly Alleviates Development of Supravalvular Aortic Stenosis
CONCLUSIONS: We demonstrate de novo elastin deposition normalizes SVAS human induced pluripotent stem cell-derived vascular smooth muscle cell hyperproliferation and rescues hypertension and aortic mechanics in Eln± mice, providing critical preclinical findings for the future application of epigallocatechin gallate treatment in humans.PMID:38752350 | DOI:10.1161/ATVBAHA.124.320790 (Source: Arteriosclerosis, Thrombosis and Vascular Biology)
Source: Arteriosclerosis, Thrombosis and Vascular Biology - May 16, 2024 Category: Cardiology Authors: Matthew W Ellis Muhammad Riaz Yan Huang Christopher W Anderson Marie Hoareau Xin Li Hangqi Luo Seoyeon Lee Jinkyu Park Jiesi Luo Luke D Batty Qunhua Huang Colleen A Lopez Dieter P Reinhardt George Tellides Yibing Qyang Source Type: research
Venous thromboembolism among Asian populations with localized colorectal cancer undergoing curative resection: is pharmacological thromboprophylaxis required? A systematic review and meta-analysis
CONCLUSION: The benefit of PTP in reducing VTE incidence among Asian patients undergoing curative resection for localized colorectal cancer has not been clearly established. The decision to administer PTP should be evaluated on a case-bycase basis and with consideration of associated bleeding risks.PMID:38752323 | DOI:10.3393/ac.2022.01046.0149 (Source: Cancer Control)
Source: Cancer Control - May 16, 2024 Category: Cancer & Oncology Authors: Shih Jia Janice Tan Emile Kwong-Wei Tan Yvonne Ying Ru Ng Rehena Sultana John Carson Allen Isaac Seow-En Ronnie Mathew Aik Yong Chok Source Type: research
Histidine-Rich Glycoprotein Modulates the Toxic Effects of High-Dose Polyphosphate in Mice
CONCLUSIONS: High-dose intravenous polyP is cardiotoxic in mice, and HRG modulates this effect.PMID:38752349 | DOI:10.1161/ATVBAHA.124.320899 (Source: Atherosclerosis)
Source: Atherosclerosis - May 16, 2024 Category: Cardiology Authors: Rida A Malik Ji Zhou James C Fredenburgh Jeff Crosby Alexey S Revenko Jeff S Healey Jeffrey I Weitz Source Type: research
Mitral Valve Replacement in Infants and Children: Five Year Outcomes of the HALO Clinical Trial
CONCLUSIONS: In small children with severe mitral valve disease requiring MVR, the 15mm SJM MHV provides satisfactory hemodynamics. Mortality and complications in these patients are not trivial. Low molecular weight heparin likely should be avoided as primary anticoagulation. Eventual valve replacement is inevitable.PMID:38750684 | DOI:10.1016/j.athoracsur.2024.04.025 (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - May 16, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Fawwaz R Shaw Brian Kogon Jonathan Chen Max B Mitchell Charles Fraser Kirk Kanter Source Type: research
Comparison of apixaban versus aspirin for the prevention of latent bioprosthetic aortic valve thrombosis: study protocol for a prospective randomized trial
The optimal antithrombotic strategy early after aortic valve replacement surgery with a biological valve remains controversial due to lack of high-quality evidence. Either oral anticoagulants or acetylsalicyli... (Source: Trials)
Source: Trials - May 16, 2024 Category: General Medicine Authors: Tomislav Kopjar, Hrvoje Gasparovic, Maja Hrabak Paar, Daniel Lovric, Petra Cerina, Tomislav Tokic and Davor Milicic Tags: Study protocol Source Type: research
