Update on Venous Thromboembolism in Orthopaedic Trauma Surgery
J Am Acad Orthop Surg. 2024 May 8. doi: 10.5435/JAAOS-D-23-00182. Online ahead of print.ABSTRACTVenous thromboembolism (VTE) is a notable contributor to the morbidity and mortality of patients with orthopaedic trauma. Several associations have published guidelines on VTE prophylaxis, with a strong predilection toward low-molecular-weight heparin for chemoprophylaxis. However, previous recommendations may be revisited because recent high-level evidence demonstrated aspirin to be noninferior to low-molecular-weight heparin in preventing serious complications of VTE. Direct oral anticoagulants are emerging as safe alternative...
Source: The Journal of the American Academy of Orthopaedic Surgeons - May 9, 2024 Category: Orthopaedics Authors: Jonathan H Wills Greg E Gaski Source Type: research
Delayed Diagnosis of Pulmonary Artery Thrombosis in a Patient Undergoing Mitral Valve Replacement
We report an unusual case of pulmonary artery thrombus in a patient with rheumatic MS which was diagnosed with transoesophageal echocardiography after MVR.PMID:38722126 | PMC:PMC10876139 | DOI:10.4103/aca.aca_45_23 (Source: Annals of Cardiac Anaesthesia)
Source: Annals of Cardiac Anaesthesia - May 9, 2024 Category: Anesthesiology Authors: Devishree Das Neeti Makhija Suruchi Hasija Mohit Prakash Source Type: research
Confounding Factors Responsible for Elevated Lp(a) Levels in Patients with Coronary Artery Disease
CONCLUSION: The findings highlight the potential significance of Lp(a) as a notable risk factor in cardiovascular health. The observed associations between elevated Lp(a) and adverse cardiovascular events, including ACS, underscore its pathogenic role. Consequently, this study supports the rationale for further research into Lp(a)-specific therapeutic interventions, offering substantial promise in refining the management strategies for cardiovascular diseases.PMID:38722118 | PMC:PMC10876127 | DOI:10.4103/aca.aca_88_23 (Source: Annals of Cardiac Anaesthesia)
Source: Annals of Cardiac Anaesthesia - May 9, 2024 Category: Anesthesiology Authors: Navaneeth Amin Tom Devasia Shobha Ullas Kamath Ganesh Paramasivam Prasad Narayana Shetty Ajit Singh Ganesha N S Prakash Source Type: research
A Case of Non-Seminomatous Germ Cell Tumor Complicated by Tumor Thrombus in an Active Duty Soldier
We present a case of tumor thrombus in a 21-year-old active duty male with a newly diagnosed stage IIIB non-seminomatous germ cell tumor presenting with extensive left lower extremity swelling. Ultrasound with Doppler was notable for significant thrombus of the left common femoral, femoral, and popliteal vein. Computed tomography imaging revealed extensive thrombus of the inferior vena cava, left iliac veins, and left gonadal vein with sparing of the left renal vein. Endovascular thrombectomy was performed with pathologic analysis confirming the presence of malignant cells consistent with tumor thrombus. The patient contin...
Source: Military Medicine - May 9, 2024 Category: International Medicine & Public Health Authors: Matthew Grossmann Chung-Ting J Kou Breanne Vergonet Matthew Soderstrom Matthew J Rendo Lauren E Lee Source Type: research
Arrhythmogenic Manifestations of Chagas Disease: Perspectives From the Bench to Bedside
This article will review the data from experimental studies and translate those findings to draw hypotheses about clinical observations. Human- and animal-based studies at molecular, cellular, tissue, and organ levels suggest 5 main pillars of remodeling caused by the interaction of host and parasite: immunologic, electrical, autonomic, microvascular, and contractile. Integrating these 5 remodeling processes will bring insights into the current knowledge in the field, highlighting some key features for future management of this arrhythmogenic disease.PMID:38723031 | DOI:10.1161/CIRCRESAHA.124.324507 (Source: Circulation Research)
Source: Circulation Research - May 9, 2024 Category: Cardiology Authors: Danilo Roman-Campos Jos é Antonio Marin-Neto Artur Santos-Miranda Nathan Kong Andr é D'Avila Anis Rassi Source Type: research
