Reactive Oxygen Species-Responsive Nano-platform with Dual-Targeting and Fluorescent Lipid-Specific Imaging Capabilities for the management of Atherosclerotic Plaques
This study provides a valuable reference for evaluating the performance of such fluorescent dyes, and offers a promising perspective on the design of the target delivery systems for atherosclerosis.PMID:38734284 | DOI:10.1016/j.actbio.2024.05.011 (Source: Atherosclerosis)
Source: Atherosclerosis - May 11, 2024 Category: Cardiology Authors: Zhigui He Qiao Chen Xinmei Duan Yuan Zhong Li Zhu Nianlian Mou Xu Yang Yu Cao Zhiqiang Han Houhua He Shuai Wu Guixue Wang Xian Qin Kai Qu Kun Zhang Jie Liu Wei Wu Source Type: research
Recent Advances in Thrombosis and Hemostasis-Part X
Semin Thromb Hemost. 2024 May 11. doi: 10.1055/s-0044-1786753. Online ahead of print.NO ABSTRACTPMID:38733980 | DOI:10.1055/s-0044-1786753 (Source: Atherosclerosis)
Source: Atherosclerosis - May 11, 2024 Category: Cardiology Authors: Sam Schulman Source Type: research
Bilateral renal lymphangiectasia: Literature review of a rare entity
Saudi Med J. 2024 May;45(5):537-540. doi: 10.15537/smj.2024.45.5.20231019.ABSTRACTRenal lymphangiectasia (RL) is a rare condition in which lymphatic vessels are dilated giving rise to cyst formation in peripelvic, perirenal and intrarenal locations. Knowledge about RL is limited and based upon individual case reports. This can be genetic or acquired. There is no significant association with any gender or age. It can be manifested as focal or diffuse forms and can be unilateral or bilateral. Most of the cases present with abdominal or flank pain. The diagnosis is based on radiological imaging. Due to rarity of diseases, it ...
Source: Saudi Medical Journal - May 11, 2024 Category: Middle East Health Authors: Abdullah Ayed Shahzada Khalid Sohail Syeda Fatima Rizvi Raed I Alwadai Source Type: research
Reactive Oxygen Species-Responsive Nano-platform with Dual-Targeting and Fluorescent Lipid-Specific Imaging Capabilities for the management of Atherosclerotic Plaques
This study provides a valuable reference for evaluating the performance of such fluorescent dyes, and offers a promising perspective on the design of the target delivery systems for atherosclerosis.PMID:38734284 | DOI:10.1016/j.actbio.2024.05.011 (Source: Atherosclerosis)
Source: Atherosclerosis - May 11, 2024 Category: Cardiology Authors: Zhigui He Qiao Chen Xinmei Duan Yuan Zhong Li Zhu Nianlian Mou Xu Yang Yu Cao Zhiqiang Han Houhua He Shuai Wu Guixue Wang Xian Qin Kai Qu Kun Zhang Jie Liu Wei Wu Source Type: research
Recent Advances in Thrombosis and Hemostasis-Part X
Semin Thromb Hemost. 2024 May 11. doi: 10.1055/s-0044-1786753. Online ahead of print.NO ABSTRACTPMID:38733980 | DOI:10.1055/s-0044-1786753 (Source: Atherosclerosis)
Source: Atherosclerosis - May 11, 2024 Category: Cardiology Authors: Sam Schulman Source Type: research
Unexplained massive pulmonary embolism in acromegaly patient: A case report
We present the case of a 36-year-old male with a history of acromegaly who presented with acute dyspnea, chest pain, and cough. Despite a prior trans-sphenoidal hypophysectomy, his acromegaly symptoms persisted. Upon evaluation, he was found to have bilateral pulmonary embolism. Thorough thrombophilia workup was unremarkable, suggesting acromegaly as a potential risk factor for VTE. (Source: Clinical Case Reports)
Source: Clinical Case Reports - May 11, 2024 Category: General Medicine Authors: Usamah Al ‐Anbagi,
Shybin Usman,
Abdulrahman Saad,
Abdulqadir J. Nashwan Tags: CASE REPORT Source Type: research
Differences in quality of anticoagulation care delivery according to ethnoracial group in the United States: A scoping review
AbstractAnticoagulation therapy is standard for conditions like atrial fibrillation, venous thromboembolism, and valvular heart disease, yet it is unclear if there are ethnoracial disparities in its quality and delivery in the United States. For this scoping review, electronic databases were searched for publications between January 1, 2011 – March 30, 2022. Eligible studies included all study designs, any setting within the United States, patients prescribed anticoagulation for any indication, outcomes reported for ≥ 2 distinct ethnoracial groups. The following four research questions were explored: Do ethnoracial...
Source: Journal of Thrombosis and Thrombolysis - May 11, 2024 Category: Hematology Source Type: research
Cardiovascular Benefits of GLP-1 Receptor Agonists in Patients Living with Obesity or Overweight: A Meta-analysis of Randomized Controlled Trials
ConclusionsIn patients living with obesity or overweight, GLP-1 RA reduced systolic and diastolic blood pressure and the occurrence of myocardial infarction, with a neutral effect on the occurrence of UA, stroke, AF, and deep vein thrombosis.RegistrationPROSPERO identifier number CRD42023475226. (Source: American Journal of Cardiovascular Drugs)
Source: American Journal of Cardiovascular Drugs - May 11, 2024 Category: Cardiology Source Type: research
The Next, Next-Generation of Sequencing, Promising to Boost Research and Clinical Practice
Semin Thromb Hemost DOI: 10.1055/s-0044-1786756 Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents | Full text (Source: Seminars in Thrombosis and Hemostasis)
Source: Seminars in Thrombosis and Hemostasis - May 11, 2024 Category: Hematology Authors: Kumar, Kishore R. Cowley, Mark J. Davis, Ryan L. Tags: Commentary Source Type: research
Heparins May Not Be the Optimal Anticoagulants for Sepsis and Sepsis-Associated Disseminated Intravascular Coagulation
Semin Thromb Hemost DOI: 10.1055/s-0044-1786754Historically, heparin has had the longest historical use as an anticoagulant and continues this day to be the primary therapeutic option for preventing thrombosis and thromboembolism in critically ill hospitalized patients. Heparin is also used to treat sepsis and sepsis-associated disseminated intravascular coagulation (DIC) in various countries. However, the efficacy and safety of heparin for this indication remains controversial, as adequately powered randomized clinical studies have not demonstrated as yet a survival benefit in sepsis and sepsis-associated DIC, despite met...
Source: Seminars in Thrombosis and Hemostasis - May 11, 2024 Category: Hematology Authors: Iba, Toshiaki Helms, Julie Totoki, Takaaki Levy, Jerrold H. Tags: Commentary Source Type: research
Evaluating Diagnostic Algorithms for Heparin-Induced Thrombocytopenia using Two Combined Automated Rapid Immunoassays
Semin Thromb Hemost DOI: 10.1055/s-0044-1786749Heparin-induced thrombocytopenia (HIT) is an autoimmune disorder caused by antibodies against platelet factor 4 (PF4) and heparin complexes. Rapid immunoassays (IAs) for detection of these antibodies mark a milestone in HIT diagnosis, despite a higher false-positive rate compared with functional platelet-activation assays. However, combining different rapid IAs may help to improve their diagnostic specificity. Here, we compared the individual performance of the latex immunoturbidimetric assay (LIA; HemosIL HIT-Ab [PF4-H]; sensitivity 91.7%, specificity 68.4%) and chemiluminesc...
Source: Seminars in Thrombosis and Hemostasis - May 11, 2024 Category: Hematology Authors: Bissola, Anna-Lise Zhang, Yi Cranstone, Madison Moore, Jane C. Warkentin, Theodore E. Arnold, Donald M. Nazy, Ishac Tags: Review Article Source Type: research
Recent Advances in Thrombosis and Hemostasis —Part X
Semin Thromb Hemost DOI: 10.1055/s-0044-1786753 Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents | Full text (Source: Seminars in Thrombosis and Hemostasis)
Source: Seminars in Thrombosis and Hemostasis - May 11, 2024 Category: Hematology Authors: Schulman, Sam Tags: Preface Source Type: research
Prone Position and the Risk of Venous Thrombosis in COVID-19 Patients with Respiratory Failure
Semin Thromb Hemost DOI: 10.1055/s-0044-1786735 Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents | Full text (Source: Seminars in Thrombosis and Hemostasis)
Source: Seminars in Thrombosis and Hemostasis - May 11, 2024 Category: Hematology Authors: Lippi, Giuseppe Mattiuzzi, Camilla Favaloro, Emmanuel J. Tags: Commentary Source Type: research
Nonsevere Hemophilia: The Need for a Renewed Focus and Improved Outcomes
Semin Thromb Hemost DOI: 10.1055/s-0044-1786358People with nonsevere hemophilia (PWNSH) are phenotypically more diverse than those with severe hemophilia. Perceptions relating to a “nonsevere” phenotype have contributed to fewer research initiatives, fewer guidelines on optimal management, and a lack of standards for surveillance and clinical assessment for affected individuals. In many cases, episodes of abnormal bleeding could, if investigated, have led to earlier diagnosis. Furthermore, the major recent developments in therapy for hemophilia have largely focused on severe disease and, as a group, PWNSH have not been...
Source: Seminars in Thrombosis and Hemostasis - May 11, 2024 Category: Hematology Authors: Dolan, Gerard Fijnvandraat, Karin Lenting, Peter J. Catarino, Cristina Lavin, Michelle Tags: Review Article Source Type: research
Thrombophilia Screening: Not So Straightforward
Semin Thromb Hemost DOI: 10.1055/s-0044-1786807Although inherited thrombophilias are lifelong risk factors for a first thrombotic episode, progression to thrombosis is multifactorial and not all individuals with inherited thrombophilia develop thrombosis in their lifetimes. Consequently, indiscriminate screening in patients with idiopathic thrombosis is not recommended, since presence of a thrombophilia does not necessarily predict recurrence or influence management, and testing should be selective. It follows that a decision to undertake laboratory detection of thrombophilia should be aligned with a concerted effort to id...
Source: Seminars in Thrombosis and Hemostasis - May 11, 2024 Category: Hematology Authors: Moore, Gary W. Tags: Review Article Source Type: research
