Clinical Effect of Microneedle Injection Combined with Blood Transfusion in the Treatment of Severe Anemia Complicated with Vitiligo under Regenerative Medical Technology
Biomed Res Int. 2022 Jul 29;2022:7117627. doi: 10.1155/2022/7117627. eCollection 2022.ABSTRACTTo explore the clinical efficacy of microneedle injection combined with blood transfusion in the treatment of severe anemia complicated with vitiligo based on regenerative medical technology and provide the theoretical basis for the adoption of microneedle technology, 60 patients with severe anemia complicated with vitiligo were selected as research objects. With 15 patients in each group, they were randomly assigned to the control group (calcipotriol ointment external application), observation group A (external application of moi...
Source: Biomed Res - August 8, 2022 Category: Research Authors: Tao He Li Gong Source Type: research
Clinical Effect of Microneedle Injection Combined with Blood Transfusion in the Treatment of Severe Anemia Complicated with Vitiligo under Regenerative Medical Technology
Biomed Res Int. 2022 Jul 29;2022:7117627. doi: 10.1155/2022/7117627. eCollection 2022.ABSTRACTTo explore the clinical efficacy of microneedle injection combined with blood transfusion in the treatment of severe anemia complicated with vitiligo based on regenerative medical technology and provide the theoretical basis for the adoption of microneedle technology, 60 patients with severe anemia complicated with vitiligo were selected as research objects. With 15 patients in each group, they were randomly assigned to the control group (calcipotriol ointment external application), observation group A (external application of moi...
Source: Biomed Res - August 8, 2022 Category: Research Authors: Tao He Li Gong Source Type: research
Clinical efficacy and safety of using calcipotriol –betamethasone compounding agent for psoriasis treatment: a systematic review and meta-analysis
AbstractThe main objective is to evaluate clinical efficacy and safety of using calcipotriol –betamethasone compounding agent for psoriasis treatment through a systematic review and meta-analysis. We searched MEDLINE, Embase, The Cochrane Library, China National Knowledge Infrastructure (CNKI), China Biomedical Literature Database (CBM), and WanFang Data from inception till July 31, 2020. Efficacy was evaluated based on primary outcome indicators including skin lesion improvement and overall adverse reaction rate. Secondary outcome indicators included degree of life quality improvement, clinical effectiveness rate, and s...
Source: Archives of Dermatological Research - July 28, 2022 Category: Dermatology Source Type: research
Matching-adjusted indirect comparison of efficacy outcomes in trials of calcipotriol plus betamethasone dipropionate foam and cream formulations for the treatment of plaque psoriasis
CONCLUSIONS: Use of Cal/BD foam consistently shows significantly greater improvements in PGA and mPASI outcomes, compared with Cal/BD cream.PMID:35875991 | DOI:10.1080/09546634.2022.2095330 (Source: Journal of Dermatological Treatment)
Source: Journal of Dermatological Treatment - July 25, 2022 Category: Dermatology Authors: Kim A Papp Henrik Thoning Sascha Gerdes Matteo Megna Henrik Brandi Marie Y Jablonski Bernasconi Oriol Y élamos Source Type: research
Clinical efficacy and safety of using calcipotriol –betamethasone compounding agent for psoriasis treatment: a systematic review and meta-analysis
AbstractThe main objective is to evaluate clinical efficacy and safety of using calcipotriol –betamethasone compounding agent for psoriasis treatment through a systematic review and meta-analysis. We searched MEDLINE, Embase, The Cochrane Library, China National Knowledge Infrastructure (CNKI), China Biomedical Literature Database (CBM), and WanFang Data from inception till July 31, 2020. Efficacy was evaluated based on primary outcome indicators including skin lesion improvement and overall adverse reaction rate. Secondary outcome indicators included degree of life quality improvement, clinical effectiveness rate, and s...
Source: Archives of Dermatological Research - July 22, 2022 Category: Dermatology Source Type: research
815 T helper 2 cell immunity eliminates pre-cancerous skin lesions
Actinic keratosis (AK) is a precursor to cutaneous squamous cell carcinoma (SCC). Effective therapeutics to eliminate AKs and prevent SCC are lacking. Long treatment durations and severe side effects have limited the efficacy of cytotoxic AK treatments including 5-fluorouracil (5-FU) chemotherapy and photodynamic therapy. Previously, we have shown that thymic stromal lymphopoietin (TSLP), an epithelium-derived cytokine, induces a robust antitumor immunity in the skin. Since this discovery, we have demonstrated the high efficacy of calcipotriol, a topical TSLP inducer, in combination with 5-fluorouracil (5-FU) as a novel im...
Source: Journal of Investigative Dermatology - July 20, 2022 Category: Dermatology Authors: T. Oka, M. Azin, T. Cunningham, M. Tabacchi, L. Cornelius, S. Demehri Source Type: research
581 Topical calcipotriol plus imiquimod immunotherapy for non-keratinocyte skin cancers
Non-keratinocyte cutaneous malignancies including breast cancer cutaneous metastasis and melanoma in situ are often poor surgical candidates due to their anatomical location, size and the morbidities associated with surgery. Imiquimod, a toll-like receptor 7 agonist, is used for the treatment of these cutaneous malignancies, which activates the innate immunity in the skin. However, imiquimod ’s modest effect on the activation of adaptive immunity limits its efficacy as a monotherapy. We have previously demonstrated that topical induction of thymic stromal lymphopoietin (TSLP) cytokine by calcipotriol protects against ski...
Source: Journal of Investigative Dermatology - July 20, 2022 Category: Dermatology Authors: M. Azin, K.H. Ngo, S. Demehri Source Type: research
Efficacy and safety of external application of Chinese herbal medicine for psoriasis vulgaris: a systematic review of randomized controlled trials
CONCLUSIONS: Current evidence showed that CHM bath and fumigation appeared to be efficient and safe for PV treatment. However, no definite conclusion could be drawn due to the low quality of included studies and thus more well-designed studies are needed for further assessment.PMID:35848965 | DOI:10.19852/j.cnki.jtcm.20220617.001 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - July 18, 2022 Category: Complementary Medicine Authors: Lin Yi L I Xun Wang Zi Zheng Xiaoran Hang Haiyan L I Lingling Source Type: research
Efficacy and safety of external application of Chinese herbal medicine for psoriasis vulgaris: a systematic review of randomized controlled trials
CONCLUSIONS: Current evidence showed that CHM bath and fumigation appeared to be efficient and safe for PV treatment. However, no definite conclusion could be drawn due to the low quality of included studies and thus more well-designed studies are needed for further assessment.PMID:35848965 | DOI:10.19852/j.cnki.jtcm.20220617.001 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - July 18, 2022 Category: Complementary Medicine Authors: Lin Yi L I Xun Wang Zi Zheng Xiaoran Hang Haiyan L I Lingling Source Type: research
Efficacy and safety of external application of Chinese herbal medicine for psoriasis vulgaris: a systematic review of randomized controlled trials
CONCLUSIONS: Current evidence showed that CHM bath and fumigation appeared to be efficient and safe for PV treatment. However, no definite conclusion could be drawn due to the low quality of included studies and thus more well-designed studies are needed for further assessment.PMID:35848965 | DOI:10.19852/j.cnki.jtcm.20220617.001 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - July 18, 2022 Category: Complementary Medicine Authors: Lin Yi L I Xun Wang Zi Zheng Xiaoran Hang Haiyan L I Lingling Source Type: research
Efficacy and safety of external application of Chinese herbal medicine for psoriasis vulgaris: a systematic review of randomized controlled trials
CONCLUSIONS: Current evidence showed that CHM bath and fumigation appeared to be efficient and safe for PV treatment. However, no definite conclusion could be drawn due to the low quality of included studies and thus more well-designed studies are needed for further assessment.PMID:35848965 | DOI:10.19852/j.cnki.jtcm.20220617.001 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - July 18, 2022 Category: Complementary Medicine Authors: Lin Yi L I Xun Wang Zi Zheng Xiaoran Hang Haiyan L I Lingling Source Type: research
Efficacy and safety of external application of Chinese herbal medicine for psoriasis vulgaris: a systematic review of randomized controlled trials
CONCLUSIONS: Current evidence showed that CHM bath and fumigation appeared to be efficient and safe for PV treatment. However, no definite conclusion could be drawn due to the low quality of included studies and thus more well-designed studies are needed for further assessment.PMID:35848965 | DOI:10.19852/j.cnki.jtcm.20220617.001 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - July 18, 2022 Category: Complementary Medicine Authors: Lin Yi L I Xun Wang Zi Zheng Xiaoran Hang Haiyan L I Lingling Source Type: research
Efficacy and safety of external application of Chinese herbal medicine for psoriasis vulgaris: a systematic review of randomized controlled trials
CONCLUSIONS: Current evidence showed that CHM bath and fumigation appeared to be efficient and safe for PV treatment. However, no definite conclusion could be drawn due to the low quality of included studies and thus more well-designed studies are needed for further assessment.PMID:35848965 | DOI:10.19852/j.cnki.jtcm.20220617.001 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - July 18, 2022 Category: Complementary Medicine Authors: Lin Yi L I Xun Wang Zi Zheng Xiaoran Hang Haiyan L I Lingling Source Type: research
