Prevalence and characteristics of erectile dysfunction in coronary patients in Abidjan Heart Institute of C ôte d'ivoire
CONCLUSION: Isolated ED appears as an early marker of generalized endothelial dysfunction. Hence the advantage of systematic screening, especially in subjects at risk of cardiovascular disease.PMID:36549938 | DOI:10.1016/j.ancard.2022.11.010 (Source: Annales de Cardiologie et d'Angeiologie)
Source: Annales de Cardiologie et d'Angeiologie - December 22, 2022 Category: Cardiology Authors: O Mahamat-Azaki A Ekou E Soya R N'guetta Source Type: research
Prevalence and characteristics of erectile dysfunction in coronary patients in Abidjan Heart Institute of C ôte d'ivoire
CONCLUSION: Isolated ED appears as an early marker of generalized endothelial dysfunction. Hence the advantage of systematic screening, especially in subjects at risk of cardiovascular disease.PMID:36549938 | DOI:10.1016/j.ancard.2022.11.010 (Source: Annales de Cardiologie et d'Angeiologie)
Source: Annales de Cardiologie et d'Angeiologie - December 22, 2022 Category: Cardiology Authors: O Mahamat-Azaki A Ekou E Soya R N'guetta Source Type: research
Computational and experimental therapeutic efficacy analysis of andrographolide phospholipid complex self-assembled nanoparticles against Neuro2a cells
CONCLUSION: Self-assembled soft ANSPC nanoparticles warrant further in-depth antitumor study in xenograft model of neuroblastoma to establish the anticancer potential.PMID:36414179 | DOI:10.1016/j.bbagen.2022.130283 (Source: Biochimica et Biophysica Acta)
Source: Biochimica et Biophysica Acta - November 22, 2022 Category: Biochemistry Authors: Atul Mourya Purva Pingle Chanti Katta Babu Veerabroma Hartisree Vaskuri G S Sainaga Jyothi Jurica Novak Prateek Pathak Maria Grishina Amita Verma Rahul Kumar Pankaj Kumar Singh Dharmendra Kumar Khatri Shashi Bala Singh Jitender Madan Source Type: research
Computational and experimental therapeutic efficacy analysis of andrographolide phospholipid complex self-assembled nanoparticles against Neuro2a cells
CONCLUSION: Self-assembled soft ANSPC nanoparticles warrant further in-depth antitumor study in xenograft model of neuroblastoma to establish the anticancer potential.PMID:36414179 | DOI:10.1016/j.bbagen.2022.130283 (Source: Biochimica et Biophysica Acta)
Source: Biochimica et Biophysica Acta - November 22, 2022 Category: Biochemistry Authors: Atul Mourya Purva Pingle Chanti Katta Babu Veerabroma Hartisree Vaskuri G S Sainaga Jyothi Jurica Novak Prateek Pathak Maria Grishina Amita Verma Rahul Kumar Pankaj Kumar Singh Dharmendra Kumar Khatri Shashi Bala Singh Jitender Madan Source Type: research
Asiatic Acid Fabricated Nanoconstructs to Mitigate Amyloid Beta1-42 Induced Injury in SH-SY5Y Cells In-Vitro and Ameliorates Cognitive Impairment by Dual Cholinesterase Inhibition and Attenuation of Oxidative Stress In-Vivo
ConclusionsHence, developed AAN has neuroprotective potential and should be further considered as an unconventional platform in preclinical model for the management of AD.Graphical Abstract (Source: Pharmaceutical Research)
Source: Pharmaceutical Research - November 14, 2022 Category: Drugs & Pharmacology Source Type: research
Innovative feedstocks for optimal mass production of the edible long-horned grasshopper, Ruspolia differens
The edible long-horned grasshopper Ruspolia differens Serville (Orthoptera:Tettigoniidae) is a highly nutritious food source consumed in over 20 African countries. Its occurrence is highly seasonal, and wild harvesting is carried out using locally designed and inefficient light traps, thus limiting sustainable utilization as an important food source. To ensure year-round production and availability of R. differens, we evaluated the effects of low-cost and affordable diets based on agricultural by-products on their growth performance, survival, fecundity, and longevity. A total of four diets with varying ratios of agricultu...
Source: Frontiers in Physiology - November 9, 2022 Category: Physiology Source Type: research
Antigenicity of subregions of recombinant bovine leukemia virus (BLV) glycoprotein gp51 for antibody detection
In this study, ten different subregions of gp51 containing a common B cell epitope are vital for developing antigens as epitope-driven vaccine design and immunological assays. Such antigens were produced in Escherichia coli expression system to react with antibodies in the serum from BLV-infected cattle and compete for antigenicity. Recombinant His-gp5156-110 and gp5133-301(full) had the same sensitivity in BLV-positive sera, indicating that antibodies responded to the limited subregion of viral gp51, a common B cell epitope. This finding provides significant information for antigen selection in BLV to use in antibody dete...
Source: Journal of Virological Methods - November 4, 2022 Category: Virology Authors: Lanlan Bai Mariko Soya Minori Ichikawa Ryosuke Matsuura Yutaka Arimura Satoshi Wada Yoko Aida Source Type: research
Antigenicity of subregions of recombinant bovine leukemia virus (BLV) glycoprotein gp51 for antibody detection
In this study, ten different subregions of gp51 containing a common B cell epitope are vital for developing antigens as epitope-driven vaccine design and immunological assays. Such antigens were produced in Escherichia coli expression system to react with antibodies in the serum from BLV-infected cattle and compete for antigenicity. Recombinant His-gp5156-110 and gp5133-301(full) had the same sensitivity in BLV-positive sera, indicating that antibodies responded to the limited subregion of viral gp51, a common B cell epitope. This finding provides significant information for antigen selection in BLV to use in antibody dete...
Source: Journal of Virological Methods - November 4, 2022 Category: Virology Authors: Lanlan Bai Mariko Soya Minori Ichikawa Ryosuke Matsuura Yutaka Arimura Satoshi Wada Yoko Aida Source Type: research
Antigenicity of subregions of recombinant bovine leukemia virus (BLV) glycoprotein gp51 for antibody detection
In this study, ten different subregions of gp51 containing a common B cell epitope are vital for developing antigens as epitope-driven vaccine design and immunological assays. Such antigens were produced in Escherichia coli expression system to react with antibodies in the serum from BLV-infected cattle and compete for antigenicity. Recombinant His-gp5156-110 and gp5133-301(full) had the same sensitivity in BLV-positive sera, indicating that antibodies responded to the limited subregion of viral gp51, a common B cell epitope. This finding provides significant information for antigen selection in BLV to use in antibody dete...
Source: Journal of Virological Methods - November 4, 2022 Category: Virology Authors: Lanlan Bai Mariko Soya Minori Ichikawa Ryosuke Matsuura Yutaka Arimura Satoshi Wada Yoko Aida Source Type: research
Intakes of major food groups in China and UK: results from 100,000 adults in the China Kadoorie biobank and UK biobank
ConclusionThe large differences in dietary intakes and their associations with SES and BMI could provide insight into the interpretation of potentially different diet –disease associations between CKB and UKB. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - October 22, 2022 Category: Nutrition Source Type: research
< em > Pseudomonas oryzagri < /em > sp. nov., isolated from a rice field soil
Int J Syst Evol Microbiol. 2022 Oct;72(10). doi: 10.1099/ijsem.0.005534.ABSTRACTA Gram-stain-negative, aerobic, rod-shaped and non-motile novel bacterial strain, designated MAHUQ-58T, was isolated from soil sample of a rice field. The colonies were observed to be light pink-coloured, smooth, spherical and 0.6-1.0 mm in diameter when grown on nutrient agar (NA) medium for 2 days. Strain MAHUQ-58T was found to be able to grow at 15-40 °C, at pH 5.5-10.0 and with 0-1.0 % NaCl (w/v). Cell growth occurred on tryptone soya agar, Luria-Bertani agar, NA, MacConkey agar and Reasoner's 2A agar. The strain was found to be positive f...
Source: International Journal of Systematic and Evolutionary Microbiology - October 18, 2022 Category: Microbiology Authors: Md Amdadul Huq Sun-Young Lee Juncai Ma M Mizanur Rahman Md Shahedur Rahman Jong-Hyun Park Shahina Akter Source Type: research
< em > Pseudomonas oryzagri < /em > sp. nov., isolated from a rice field soil
Int J Syst Evol Microbiol. 2022 Oct;72(10). doi: 10.1099/ijsem.0.005534.ABSTRACTA Gram-stain-negative, aerobic, rod-shaped and non-motile novel bacterial strain, designated MAHUQ-58T, was isolated from soil sample of a rice field. The colonies were observed to be light pink-coloured, smooth, spherical and 0.6-1.0 mm in diameter when grown on nutrient agar (NA) medium for 2 days. Strain MAHUQ-58T was found to be able to grow at 15-40 °C, at pH 5.5-10.0 and with 0-1.0 % NaCl (w/v). Cell growth occurred on tryptone soya agar, Luria-Bertani agar, NA, MacConkey agar and Reasoner's 2A agar. The strain was found to be positive f...
Source: International Journal of Systematic and Evolutionary Microbiology - October 18, 2022 Category: Microbiology Authors: Md Amdadul Huq Sun-Young Lee Juncai Ma M Mizanur Rahman Md Shahedur Rahman Jong-Hyun Park Shahina Akter Source Type: research
Trypsin Inhibitor Isolated From Glycine max (Soya Bean) Extraction, Purification, and Characterization
Dose Response. 2022 Oct 12;20(4):15593258221131462. doi: 10.1177/15593258221131462. eCollection 2022 Oct-Dec.ABSTRACTThe current study aims to isolate, purify, and characterize the trypsin inhibitor protein from seeds of soya beans, scientifically known as Glycine max. Its seeds were ground, and the powder was soaked several times using n-hexane. It was added to phosphate buffer saline (PBS) followed by filtration and centrifugation of the PBS dissolved extract. The supernatant was subjected to ammonium sulfate precipitation and about six fractions, 30% to 80% were prepared. The centrifuged pellets obtained from each fract...
Source: Dose Response - October 17, 2022 Category: Drugs & Pharmacology Authors: Sabir Khan Shafia Arshad Amina Arif Rida Tanveer Zeemal Seemab Amin Saba Abbas Amna Maqsood Muhammad Raza Arooj Munir Amara Latif Maryam Habiba Muhammad Afzal Source Type: research
Trypsin Inhibitor Isolated From Glycine max (Soya Bean) Extraction, Purification, and Characterization
Dose Response. 2022 Oct 12;20(4):15593258221131462. doi: 10.1177/15593258221131462. eCollection 2022 Oct-Dec.ABSTRACTThe current study aims to isolate, purify, and characterize the trypsin inhibitor protein from seeds of soya beans, scientifically known as Glycine max. Its seeds were ground, and the powder was soaked several times using n-hexane. It was added to phosphate buffer saline (PBS) followed by filtration and centrifugation of the PBS dissolved extract. The supernatant was subjected to ammonium sulfate precipitation and about six fractions, 30% to 80% were prepared. The centrifuged pellets obtained from each fract...
Source: Dose Response - October 17, 2022 Category: Drugs & Pharmacology Authors: Sabir Khan Shafia Arshad Amina Arif Rida Tanveer Zeemal Seemab Amin Saba Abbas Amna Maqsood Muhammad Raza Arooj Munir Amara Latif Maryam Habiba Muhammad Afzal Source Type: research
