Spectrum of renal vascular lesions among patients with lupus nephritis: An experience from a tertiary care center
CONCLUSIONS: Renal vascular lesions are common in systemic lupus erythematosus patients with nephritis and may be associated with aggressive clinical course.PMID:38084527 | DOI:10.4103/ijpm.ijpm_327_22 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - December 12, 2023 Category: Pathology Authors: Madhumita Paul Soma Addya Moumita Sengupta Keya Basu Arpita Roychowdhury Manimoy Bandopadhyay Source Type: research

Spectrum of renal vascular lesions among patients with lupus nephritis: An experience from a tertiary care center
CONCLUSIONS: Renal vascular lesions are common in systemic lupus erythematosus patients with nephritis and may be associated with aggressive clinical course.PMID:38084527 | DOI:10.4103/ijpm.ijpm_327_22 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - December 12, 2023 Category: Pathology Authors: Madhumita Paul Soma Addya Moumita Sengupta Keya Basu Arpita Roychowdhury Manimoy Bandopadhyay Source Type: research

Spectrum of renal vascular lesions among patients with lupus nephritis: An experience from a tertiary care center
CONCLUSIONS: Renal vascular lesions are common in systemic lupus erythematosus patients with nephritis and may be associated with aggressive clinical course.PMID:38084527 | DOI:10.4103/ijpm.ijpm_327_22 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - December 12, 2023 Category: Pathology Authors: Madhumita Paul Soma Addya Moumita Sengupta Keya Basu Arpita Roychowdhury Manimoy Bandopadhyay Source Type: research

Spectrum of renal vascular lesions among patients with lupus nephritis: An experience from a tertiary care center
CONCLUSIONS: Renal vascular lesions are common in systemic lupus erythematosus patients with nephritis and may be associated with aggressive clinical course.PMID:38084527 | DOI:10.4103/ijpm.ijpm_327_22 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - December 12, 2023 Category: Pathology Authors: Madhumita Paul Soma Addya Moumita Sengupta Keya Basu Arpita Roychowdhury Manimoy Bandopadhyay Source Type: research

Spectrum of renal vascular lesions among patients with lupus nephritis: An experience from a tertiary care center
CONCLUSIONS: Renal vascular lesions are common in systemic lupus erythematosus patients with nephritis and may be associated with aggressive clinical course.PMID:38084527 | DOI:10.4103/ijpm.ijpm_327_22 (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - December 12, 2023 Category: Pathology Authors: Madhumita Paul Soma Addya Moumita Sengupta Keya Basu Arpita Roychowdhury Manimoy Bandopadhyay Source Type: research

Differential Myosin 5a splice variants in innervation of pelvic organs
This study examines the expression and distribution of Myo5a splice variants in the MPG, compared to the bladder, corpus cavernosum of the penis (CCP) and distal colon using immunohistochemistry and mRNA analyses.Results/discussion: We report detection of characteristic Myo5a variants in these tissues, with bladder and CCP displaying a similar variant pattern but one which differed from that of distal colon. In all three organs, Myo5a variants were distinct compared to the MPG, implying segregation of one variant within nerve soma and its exclusion from axons. The expression of distinct Myo5a variant arrays is likely to be...
Source: Frontiers in Physiology - December 12, 2023 Category: Physiology Source Type: research

A minimal kinetic model for the interpretation of complex catalysis in single enzyme molecules
Phys. Chem. Chem. Phys., 2024, Advance Article DOI: 10.1039/D3CP01720F, PaperPrasanta Kundu, Soma Saha, Gautam Gangopadhyay A three-state stochastic kinetic model is the minimal requirement to interpret the results of single β-galactosidase-driven conversions of resorufin-β-D-galactopyranoside into fluorogenic product resorufin. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Phys. Chem. Chem. Phys. latest articles)
Source: RSC - Phys. Chem. Chem. Phys. latest articles - December 11, 2023 Category: Chemistry Authors: Prasanta Kundu Source Type: research

Long ascending propriospinal neurons are heterogenous and subject to spinal cord injury induced anatomic plasticity
Exp Neurol. 2023 Dec 7:114631. doi: 10.1016/j.expneurol.2023.114631. Online ahead of print.ABSTRACTLong ascending propriospinal neurons (LAPNs) are a subset of spinal interneurons that provide direct connectivity between distant spinal segments. Here, we focus specifically on an anatomically defined population of "inter-enlargement" LAPNs with cell bodies at L2/3 and terminals at C5/6. Previous studies showed that silencing LAPNs in awake and freely moving animals disrupted interlimb coordination of the hindlimbs, forelimbs, and heterolateral limb pairs. Surprisingly, despite a proportion of LAPNs being anatomically intact...
Source: Experimental Neurology - December 9, 2023 Category: Neurology Authors: Brandon L Brown Neha Anil Gregory States Scott R Whittemore David S K Magnuson Source Type: research

Relationship between endocrine disrupting chemicals (phthalate metabolites, triclosan and bisphenols) and vitamin D in female subjects: An exploratory pilot study
CONCLUSION: These putative data indicate that MCPP is related to 25(OH)D3, while MiBP and MBP were related to vitamin D deficiency; however, no correlations were observed with TCS and BPs. No phthalate metabolites correlated with 1,25(OH)2D3, CaM associated proteins or renal function, suggesting that effects occur earlier in the vitamin D pathway and not through modulation of cellular calcium flux. The observed correlations are surprisingly strong compared to other predictors of 25(OH)D3, and larger studies adjusting for potential confounders are warranted.PMID:38070612 | DOI:10.1016/j.chemosphere.2023.140894 (Source: Chemosphere)
Source: Chemosphere - December 9, 2023 Category: Chemistry Authors: Edwina Brennan Alexandra E Butler Manjula Nandakumar Kristie Thompson Thozhukat Sathyapalan Stephen L Atkin Source Type: research

Relationship between endocrine disrupting chemicals (phthalate metabolites, triclosan and bisphenols) and vitamin D in female subjects: An exploratory pilot study
CONCLUSION: These putative data indicate that MCPP is related to 25(OH)D3, while MiBP and MBP were related to vitamin D deficiency; however, no correlations were observed with TCS and BPs. No phthalate metabolites correlated with 1,25(OH)2D3, CaM associated proteins or renal function, suggesting that effects occur earlier in the vitamin D pathway and not through modulation of cellular calcium flux. The observed correlations are surprisingly strong compared to other predictors of 25(OH)D3, and larger studies adjusting for potential confounders are warranted.PMID:38070612 | DOI:10.1016/j.chemosphere.2023.140894 (Source: Chemosphere)
Source: Chemosphere - December 9, 2023 Category: Chemistry Authors: Edwina Brennan Alexandra E Butler Manjula Nandakumar Kristie Thompson Thozhukat Sathyapalan Stephen L Atkin Source Type: research

Long ascending propriospinal neurons are heterogenous and subject to spinal cord injury induced anatomic plasticity
Exp Neurol. 2023 Dec 7:114631. doi: 10.1016/j.expneurol.2023.114631. Online ahead of print.ABSTRACTLong ascending propriospinal neurons (LAPNs) are a subset of spinal interneurons that provide direct connectivity between distant spinal segments. Here, we focus specifically on an anatomically defined population of "inter-enlargement" LAPNs with cell bodies at L2/3 and terminals at C5/6. Previous studies showed that silencing LAPNs in awake and freely moving animals disrupted interlimb coordination of the hindlimbs, forelimbs, and heterolateral limb pairs. Surprisingly, despite a proportion of LAPNs being anatomically intact...
Source: Experimental Neurology - December 9, 2023 Category: Neurology Authors: Brandon L Brown Neha Anil Gregory States Scott R Whittemore David S K Magnuson Source Type: research

Dried blood spot analysis for the quantification of vancomycin and creatinine using liquid chromatography - tandem mass spectrometry: method development and validation
CONCLUSION: Hence, we successfully validated a quantification method for the simultaneous determination of creatinine and vancomycin in DBS.PMID:38052384 | DOI:10.1016/j.cca.2023.117689 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - December 5, 2023 Category: Chemistry Authors: Soma Bahmany Moska Hassanzai Robert B Flint Hein A W van Onzenoort Brenda C M de Winter Birgit C P Koch Source Type: research

Dried blood spot analysis for the quantification of vancomycin and creatinine using liquid chromatography - tandem mass spectrometry: method development and validation
CONCLUSION: Hence, we successfully validated a quantification method for the simultaneous determination of creatinine and vancomycin in DBS.PMID:38052384 | DOI:10.1016/j.cca.2023.117689 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - December 5, 2023 Category: Chemistry Authors: Soma Bahmany Moska Hassanzai Robert B Flint Hein A W van Onzenoort Brenda C M de Winter Birgit C P Koch Source Type: research

Breaking barriers in antibody discovery: harnessing divergent species for accessing difficult and conserved drug targets
Volume 15, Issue 1, January-December 2023 . (Source: mAbs)
Source: mAbs - December 5, 2023 Category: Biomedical Science Authors: Soma S.R. BanikNatasha KushnirBenjamin J. DoranzRoss ChambersIntegral Molecular, Philadelphia, PA, USA Source Type: research

Hospitalizations in Adult Patients With Congenital Heart Disease in Japan
Circ J. 2023 Dec 1. doi: 10.1253/circj.CJ-23-0822. Online ahead of print.NO ABSTRACTPMID:38044146 | DOI:10.1253/circj.CJ-23-0822 (Source: Circulation Journal)
Source: Circulation Journal - December 3, 2023 Category: Cardiology Authors: Katsura Soma Atsushi Yao Source Type: research