TLC Todd-versations: Todd Linsky in Conversation with Dr. Alan Greene
Todd Linsky, a food and organic industry veteran, hosts the podcast Todd-versations. He interviews guests from around the globe — influencers, leaders, and innovators in their respective fields. In this episode, Todd and Dr. Greene discuss the pediatric roots of longevity, the importance of nutrition in health, Dr. Greene’s reasons for creating DrGreene.com, his next projects, and a whole host of side topics.
Transcript of Todd-versation Podcast with Todd Linsky and Dr. Greene
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this conversation is brought to you in part by Calavo Growers the family of fresh!
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hey there everybody good ...
Source: Conversations with Dr Greene - October 6, 2022 Category: Child Development Authors: Alan Greene MD Tags: Dr. Greene's Blog Source Type: blogs
Amazing Technologies Changing The Future Of Dermatology
Smart algorithms will soon diagnose skin cancer, dermatologists consult patients online, and 3D printers will print out synthetic skin to fight tissue shortages. There is a lot going on in dermatology, and medical professionals should prepare in time for the technological changes before they start swiping through the specialty. Let’s start by familiarising ourselves with the most amazing technologies changing the future of dermatology!
Skin cancer is too common
According to statistics from the WHO, currently, some 1.5 million non-melanoma skin cancers and 325,000 melanoma skin cancers occur globally each year. Data...
Source: The Medical Futurist - August 4, 2022 Category: Information Technology Authors: berci.mesko Tags: Future of Medicine Telemedicine & Smartphones 3d printing AI artificial intelligence digital Healthcare Innovation nanotechnology Personalized medicine robotics wearables GC1 dermatology Source Type: blogs
Fight Aging! Newsletter, June 27th 2022
In conclusion, this study confirms that innate immune training can be induced in aging healthy individuals as well as critically ill sepsis patients. We found that innate immune training can be induced regardless of age and there was no substantive difference in the immune trained phenotype as a function of age. We employed β-glucan as our immune training stimulus. The ability of glucan to induce the trained phenotype suggests that it may be possible to pharmacologically induce the immune trained phenotype in aging human immunocytes.
Sitting Time Correlates with Mortality Risk
https://www.fightaging.org/archi...
Source: Fight Aging! - June 26, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, May 30th 2022
In conclusion, fisetin supplementation may be a novel strategy to target excess cellular senescence and thereby reduce mitochondrial ROS to improve NO-mediated endothelial function with aging.
Exercise Upregulates BDNF Expression to Promote Dopamine Release and Brain Function
https://www.fightaging.org/archives/2022/05/exercise-upregulates-bdnf-expression-to-promote-dopamine-release-and-brain-function/
Researchers have in the past shown that exercise results in greater amounts of BDNF, which in turn promotes neurogenesis. Here, this line of research is extended to show that exercise results in an increa...
Source: Fight Aging! - May 29, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, February 21st 2022
In conclusion, clinical trials targeting aging in humans have shown promising but limited results on biomarkers so far.
Mycobacterium Vaccae Immunization as an Anti-Inflammatory Strategy
https://www.fightaging.org/archives/2022/02/mycobacterium-vaccae-immunization-as-an-anti-inflammatory-strategy/
In today's open access paper, researchers discuss immunization with Mycobacterium vaccae as an approach to reduce the inflammatory overactivity of the aged immune system. Researchers have made some initial inroads into studying the way in which this bacteria can alter the function of the immune system, and her...
Source: Fight Aging! - February 20, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Handheld Photoacoustic Device for Lymph Node Assessment
Researchers at Pohang University of Science & Technology in South Korea have developed a handheld photoacoustic device that can locate sentinel lymph nodes near the armpit. The technology could help clinicians to locate the correct lymph node from which to take a biopsy when checking for breast cancer metastases. At present, this process involves using radioactive probes, and so the current system can help patients and healthcare staff to avoid radiation exposure.
The lymph system provides a handy highway through the body for metastasizing cancers. Breast cancers and melanoma often hitch a ride through the lymphatic...
Source: Medgadget - September 23, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Oncology Surgery Source Type: blogs
Case of the Week 654
This week ' s case is of a middle-aged man with a painful lesion on the dorsum of his foot. He recently returned from Brazil, during which he swam in the ocean, walked barefoot on the beach, and ate local foods. An excisional biopsy was performed and submitted to the clinical microbiology lab to rule out a possible parasite. The specimen received was an excised ellipse of skin on which there was a central defect measuring ~ 5 mm in diameter:There was also a separate section of subcutaneous tissue, which contained numerous tan-white ovoid objects:Here is a close-up of these objects:To confirm our suspected diagnosis, ...
Source: Creepy Dreadful Wonderful Parasites - September 20, 2021 Category: Parasitology Source Type: blogs
Case of the Week 647
The following objects were seen on Giemsa-stained touch preps of a skin biopsy from a patient with a slowly enlarging ulcer. He had recently travelled to Costa Rica. Identification? What additional testing is indicated? (Source: Creepy Dreadful Wonderful Parasites)
Source: Creepy Dreadful Wonderful Parasites - July 27, 2021 Category: Parasitology Source Type: blogs
Fight Aging! Newsletter, June 28th 2021
In conclusion, in our prospective community-based study, aging-related biomarkers were associated with measures of subclinical atherosclerosis cross-sectionally and with all-cause mortality prospectively, supporting the concept that these biomarkers may reflect the aging process in community-dwelling adults.
The Role of Aging Macrophages in Skin Inflammation
https://www.fightaging.org/archives/2021/06/the-role-of-aging-macrophages-in-skin-inflammation/
The immune system is complex and ages in complex ways, pressed by the lifetime burden of infection and rising levels of molecular damage that trigger man...
Source: Fight Aging! - June 27, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
The Forever Healthy Foundation Knowledge Base on Dasatinib and Quercetin as a Senolytic Therapy
The Forever Healthy Foundation has been building a database of materials covering presently available options for the treatment of aging, all of which have little available data in comparison to more established areas of medicine. The bias in these materials is towards a very conservative viewpoint, appropriate for physicians, so you will see little to no enthusiasm for forging ahead with use, as the self-experimenters in the longevity community are presently doing. Nonetheless, this provides a convenient repositories of information, pulling together references to all of the animal and human data available for the topics u...
Source: Fight Aging! - June 24, 2021 Category: Research Authors: Reason Tags: Activism, Advocacy and Education Source Type: blogs
New Bioprinting Technique to Make Artificial Cartilage Implants
Researchers at the University of Alberta have developed a method to 3D print cartilage-like materials consisting of a collagen hydrogel containing human chondrocytes. The printed structures mimic human nasal cartilage in terms of its mechanical, molecular and histological characteristics. The researchers hope the technology could lead to personalized cartilage implants for skin cancer patients who have nasal cartilage defects following surgery to remove their tumors.
The nose is a common site for skin cancer, and in many such patients, removal of the cancerous lesions will result in cartilage defects. At present, surgeo...
Source: Medgadget - May 10, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Materials Orthopedic Surgery Plastic Surgery Source Type: blogs
Software Spots Suspicious Skin Lesions on Smartphone Photos
Melanoma, which accounts for over 70 percent of all skin cancers, occurs when pigment producing cells called melanocytes multiply uncontrollably. This cancer is typically diagnosed through visual inspection of Suspicious Pigmented Lesions (SPLs), and such early detection of lesions in a physician’s office are often life-saving. However, there are several disadvantages with this approach, including the high volume of potential lesions one has to biopsy and test before confirming a diagnosis.
To overcome these issues, researchers from MIT and a few other institutions around Boston, have developed a new deep learning...
Source: Medgadget - April 20, 2021 Category: Medical Devices Authors: Rukmani Sridharan Tags: Dermatology Informatics Oncology Source Type: blogs
Fight Aging! Newsletter, March 8th 2021
Conclusion
Coupled with the animal data, and the existing human trial data for safety, the results here suggests that someone should run a formal, controlled trial of flagellin immunization in older people, 65 and over. The goal would be to see whether (a) this sort of outcome holds up in a larger group of people, and (b) there is a meaningful impact on chronic inflammation and other parameters of health that are known to be affected by the aging of the gut microbiome.
The Role of Reactive Oxygen Species in Aging is Complex
https://www.fightaging.org/archives/2021/03/the-role-of-reactive-oxygen-species-in-a...
Source: Fight Aging! - March 7, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, March 1st 2021
This study may have important implications for preventing cell senescence and aging-induced tendinopathy, as well as for the selection of novel therapeutic targets of chronic tendon diseases.
Our results showed that the treatment of bleomycin, a DNA damaging agent, induced rat patellar TSC (PTSC) cellular senescence. The senescence was characterized by an increase in the senescence-associated β-galactosidase activity, as well as senescence-associated changes in cell morphology. On the other hand, rapamycin could extend lifespan in multiple species, including yeast, fruit flies, and mice, by decelerating DNA damage ...
Source: Fight Aging! - February 28, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Upregulation of Autophagy via mTOR Inhibition Reduces Tendon Stem Cell Senescence
This study may have important implications for preventing cell senescence and aging-induced tendinopathy, as well as for the selection of novel therapeutic targets of chronic tendon diseases.
Our results showed that the treatment of bleomycin, a DNA damaging agent, induced rat patellar TSC (PTSC) cellular senescence. The senescence was characterized by an increase in the senescence-associated β-galactosidase activity, as well as senescence-associated changes in cell morphology. On the other hand, rapamycin could extend lifespan in multiple species, including yeast, fruit flies, and mice, by decelerating DNA damage ...
Source: Fight Aging! - February 26, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
