Paget's disease if Nipple- Review
Clinical:Approximately 1% –3% of women with adenocarcinoma of the breast have Paget disease. Clinically-Paget disease has common dermatitis-like appearance, as originally described in 1874, when Sir James Paget recorded that such lesions may resemble “ordinary chronic eczema” or present as nipple erosion or ulceration. Paget disease often has a deceptively banal clinical morphology but should lead the list of differential diagnoses when evaluating unilateral lesions of the nipple–areola complex in adults.Paget disease presenting with nipple erosion. Most women with the histopathologic finding of Paget disease ...
Source: Oncopathology - June 28, 2013 Category: Cancer & Oncology Tags: a common misdiagnosis. breast Breast Biopsy Procedure Breast Carcinoma vs. Pulmonary Adenocarcinoma Source Type: blogs

A Call to Action on Glucosepane
Advanced glycation endproducts (AGEs) are one of the root causes of aging. Many different types of AGE are created as a byproduct of ordinary metabolic operation and also arrive in the diet. Their levels rise and fall over time depending on circumstances and the body's efforts to clear out these unwanted compounds. The hardiest forms of AGE are a challenge, however: they lurk in your tissues in growing amounts as the years pass, disrupting important biological machinery, provoking chronic inflammation, and altering cellular behavior for the worse. Of these various types of AGE the most important by far in human tissues is ...
Source: Fight Aging! - June 25, 2013 Category: Health Medicine and Bioethics Commentators Authors: Reason Tags: Daily News Source Type: blogs

"Nudging" Informed Consent Toward One Direction
Discussion Blog)
Source: Bioethics Discussion Blog - June 16, 2013 Category: Health Medicine and Bioethics Commentators Source Type: blogs

Hands on (and sometimes off) in object investigation session
As the It’s Not What You Think: Communicating Medical Materialities workshop in March, we experimented with different formats – from quick-fire intro presentations to break the interdisciplinary ice, to a hands-on object investigation session. In the object session (video here), participants were sorted into four groups, and entered an empty exhibition room to find one table per group, covered with acid-free tissue on which perched groups of objects selected from Museion’s collections. The four groups had been curated under the themes ‘metal’, ‘chemical’, ‘bodily’, a...
Source: Biomedicine on Display - June 7, 2013 Category: Medical Scientists Authors: Louise Whiteley Tags: aesthetics artefacts conferences haptics human remains INWYT medical scientific instruments senses Source Type: blogs

Prince Philip Abdominal Surgery Worrisome for Cancer?
Although we are not participating in the care of Prince Philip, husband to Queen Elizabeth of England, we have noted news reports that the prince consort is scheduled for “exploratory surgery” shortly after findings of abdominal. He was admitted to the hospital today under his own power after attending an afternoon garden party for a planned surgery for abnormal abdominal findings detected during a staged medical workup. Prince Philip is expected to be in the hospital for two weeks. This announcement by Buckingham Palace is very carefully worded and is likely not sharing all the details known to the Palace at t...
Source: Inside Surgery - June 6, 2013 Category: Surgeons Authors: Editor Tags: Medical News Wire exploratory Prince Philip Queen Elizabeth surgery Source Type: blogs

Nipple Delay Surgery
Angelina Jolie recently shared her BRCA+ diagnosis and brave decision to undergo prophylactic nipple-sparing mastectomy and immediate breast reconstruction. As part of her surgery, she underwent a nipple delay procedure.So what is a "nipple delay"?Most patients do not need a delay procedure. It's actually performed quite rarely. It can however be a good option for patients who want nipple-sparing mastectomy but are at high risk for nipple necrosis. High risk patients include smokers, patients with moderate to significant breast ptosis (sagging), and patients with a history of previous breast surgery (eg breast reducti...
Source: Breast Cancer Reconstruction Blog - May 15, 2013 Category: Cancer & Oncology Tags: Angelina Jolie BRCA breast cancer breast reconstruction nipple delay nipple necrosis nipple sparing mastectomy nipple-areolar complex nipple-sparing mastectomy prophylactic mastectomy Source Type: blogs

Nipple Delay Surgery
Angelina Jolie recently shared her BRCA+ diagnosis and brave decision to undergo prophylactic nipple-sparing mastectomy and immediate breast reconstruction. As part of her surgery, she underwent a nipple delay procedure. So what is a "nipple delay"? Most patients do not need a delay procedure. It's actually performed quite rarely. It can however be a good option for patients who want nipple-sparing mastectomy but are at high risk for nipple necrosis. High risk patients include smokers, patients with moderate to significant breast ptosis (sagging), and patients with a history of previous breast surgery (eg breast red...
Source: Breast Cancer Reconstruction Blog - May 15, 2013 Category: Cancer Tags: nipple sparing mastectomy nipple necrosis breast reconstruction breast cancer nipple delay Angelina Jolie nipple-sparing mastectomy prophylactic mastectomy BRCA nipple-areolar complex Source Type: blogs

Wheat headache
Karen tells this story of her son’s 3-month struggle with headache and other symptoms: My son suffered from chronic (nearly daily) headaches and dizziness for 3 months, missing 30+ days of school in that time. Three days after removing wheat from his diet, he is headache-free. Chronic constipation gone. Former pale skin, dark circles under his eyes: gone. Energy level back, moodiness: gone. Taking him off wheat was always my gut instinct, but we were told by everyone in the medical field that it couldn’t possibly be from a food issue. We had tried numerous medications, took every blood test possible, MRI, mass...
Source: Wheat Belly Blog - May 13, 2013 Category: Cardiology Authors: Dr. Davis Tags: Migraine headaches Wheat-elimination success stories Source Type: blogs

How one urologist approaches PSA testing
Prostate cancer is the most commonly diagnosed non–skin cancer among U.S. men. It can be life-threatening, and many men have cancer without knowing it. For those reasons, doctors sometimes look for prostate cancer in healthy men (screen for cancer) by measuring blood levels of prostate-specific antigen (PSA), a protein secreted by the prostate gland. High PSA levels can be caused by cancer and may lead a doctor to take a sample of prostate tissue to see whether cancer is present (biopsy). Most prostate cancer grows very slowly, however, and many men with prostate cancer die of other causes. Neither PSA testing nor prosta...
Source: Kevin, M.D. - Medical Weblog - May 12, 2013 Category: Family Physicians Tags: Conditions Cancer Source Type: blogs

The ABCDE's of Melanoma: 5 Letters That Can Save Your Life
True story: I've had a little spot on my face for a few years now. I've been all about ignoring it,  but it was my husband who finally insisted that I get it checked out by a dermatologist. To my surprise, when I finally made an appointment, my new doc agreed that it could be suspicious and suggested a biopsy, just in case. Turns out it really was fine, but it was certainly a wake-up call about what I could have been ignoring for years -- and not even on some tucked away body part -- on my face! (Source: The ND Blog: Notes from the Nutritionista by Monica Reinagel, L.D.N., C.N.S.)
Source: The ND Blog: Notes from the Nutritionista by Monica Reinagel, L.D.N., C.N.S. - May 10, 2013 Category: Nutritionists and Food Scientists Tags: Health cancer safety skin cancer summer sun protection sunscreen Source Type: blogs

Nipple-Sparing Mastectomy
Nipple-sparing mastectomy in conjunction with immediate breast reconstruction is becoming more and more popular so I thought a blog post about it was in order...What is a nipple-sparing mastectomy?A nipple-sparing mastectomy preserves the nipple,  areola and all the surrounding breast skin which is then used for the breast reconstruction. Unlike the traditional "modified radical mastectomy", nipple-sparing mastectomy only removes the breast tissue ("parenchyma") under the skin.What are the benefits?Studies show that nipple-sparing mastectomy provides the same level of surgical treatment as a modified radical mastectom...
Source: Breast Cancer Reconstruction Blog - April 24, 2013 Category: Cancer & Oncology Tags: BRCA breast reconstruction cowden's syndrome mastectomy modified radical mastectomy nipple areola nipple sparing mastectomy nipple-sparing prophylactic mastectomy strong family history Source Type: blogs

Breast Cancer
Pathophysiology of Breast Cancer Breast cancer is a: 1) neoplastic transformation of glandular epithelium of the terminal duct unit, lactiferous proximal ducts, or lobules of the breast 2) almost always adenocarcinoma 3) classification is controversial, but most experts recognize in situ (malignant cells do not invade through the basement membrane) and invasive forms 4) in situ types – intraductal (comedo and noncomedo sutypes) in situ, lobular in situ, and papillary in situ 5) invasive types – ductal, lobular, tubular, colloid, and medullary Signs and Symptoms 1) palpable mass – hard, irregular, no discr...
Source: Inside Surgery - March 21, 2013 Category: Surgeons Authors: Editor Tags: Breast Surgery Oncology adenocarcinoma BRCA1 BRCA2 comedo in situ invasive ductal Li Fraumeni lobular peau d'orange Source Type: blogs

Nipple-Sparing Mastectomy
Nipple-sparing mastectomy in conjunction with immediate breast reconstruction is becoming more and more popular so I thought a blog post about it was in order... What is a nipple-sparing mastectomy? A nipple-sparing mastectomy preserves the nipple,  areola and all the surrounding breast skin which is then used for the breast reconstruction. Unlike the traditional "modified radical mastectomy", nipple-sparing mastectomy only removes the breast tissue ("parenchyma") under the skin. What are the benefits? Studies show that nipple-sparing mastectomy provides the same level of surgical treatment as a modified radical ...
Source: Breast Cancer Reconstruction Blog - March 6, 2013 Category: Cancer Tags: nipple sparing mastectomy strong family history breast reconstruction cowden's syndrome modified radical mastectomy nipple-sparing nipple areola prophylactic mastectomy BRCA Source Type: blogs

Ulcerative colitis tamed
Traci posted this wonderful story of her dramatic relief from years of ulcerative colitis: Dr. Davis, For 24+ years I have suffered from Ulcerative Colitis (UC). This past Christmas, my stepmother recommend that I read your Wheat Belly book. I did because I had decided to remove carbs from my diet at the beginning of the year. She said your book would be a great supplement to my carb reduction. I had no idea that by reading your book my symptoms of UC would disappear!!! Normally, I am treated with a medicine called Remicade which is administered via IV. Usually I receive this medicine every 2 months. Guess what??? It’s ...
Source: Wheat Belly Blog - March 6, 2013 Category: Cardiology Authors: Dr. Davis Tags: Ulcerative colitis Source Type: blogs