Part One: Tapping the Wrist
The wrist is not commonly aspirated in the emergency department, but emergent arthrocentesis may be indicated for extreme or concerning cases, and tapping the wrist to determine the underlying pathology or relieve pain may be of great value. The synovial fluid from the joint space can be analyzed for crystals, infection, and blood. This information may help determine the overall plan and aid in decision-making and consultation. The ultimate treatment plan may include admission, intravenous antibiotics, multiple aspirations, and even surgical washout.A swollen, painful wrist that is hot to the touch is concerning for sep...
Source: The Procedural Pause - April 1, 2020 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
10 Ways Technology Is Changing Healthcare
The future of healthcare is shaping up in front of our very eyes with advances in digital technologies, such as artificial intelligence, VR/AR, 3D-printing, robotics or nanotechnology. We have to familiarize with the latest developments in order to be able to control technology and not the other way around. The future of healthcare lies in working hand-in-hand with technology and healthcare workers have to embrace emerging technologies in order to stay relevant in the coming years.
Be bold, curious and informed!
Are you afraid that robots will take over the jobs of nurses, doctors and other healthcare professionals? Are y...
Source: The Medical Futurist - March 3, 2020 Category: Information Technology Authors: berci.mesko Tags: Future of Medicine 3d printing AI artificial intelligence augmented reality genetics Health Healthcare nanotechnology Personalized medicine pharma pharmacology robotics virtual reality wearables GC1 Source Type: blogs
Fight Aging! Newsletter, February 10th 2020
In conclusion, the concept of an epigenetic clock is compelling, but caution should be taken in interpreting associations with age acceleration. Association tests of age acceleration should include age as a covariate.
A Discussion of Recent Work on Allotopic Expression of Mitochondrial Genes at the SENS Research Foundation
https://www.fightaging.org/archives/2020/02/a-discussion-of-recent-work-on-allotopic-expression-of-mitochondrial-genes-at-the-sens-research-foundation/
A paper published last month outlines recent progress on allotopic expression of mitochondrial genes carried out by the SENS Research...
Source: Fight Aging! - February 9, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Newer skin cancer treatments improve prognosis for those with cutaneous melanoma
Cutaneous melanoma, also called malignant melanoma, is the type of skin cancer that is most likely to spread to other parts of the body. Though melanoma accounts for only about 1% of skin cancers, it is responsible for more than 90% of skin cancer-related deaths.
But thanks to developments in skin cancer treatment (mostly in the last decade), patients with melanoma have much better chances of living longer.
What is a melanoma?
Melanoma involves the uncontrolled growth of a type of cell known as a melanocyte. One of the most important functions of a normal melanocyte is to protect your skin from the sun’s damaging ultravi...
Source: Harvard Health Blog - February 3, 2020 Category: Consumer Health News Authors: Dominic Wu, MD Tags: Cancer Skin and Hair Care Source Type: blogs
Fight Aging! Newsletter, January 6th 2020
Conclusion
A great deal of progress is being made in the matter of treating aging: in advocacy, in funding, in the research and development. It can never be enough, and it can never be fast enough, given the enormous cost in suffering and lost lives. The longevity industry is really only just getting started in the grand scheme of things: it looks vast to those of us who followed the slow, halting progress in aging research that was the state of things a decade or two ago. But it is still tiny compared to the rest of the medical industry, and it remains the case that there is a great deal of work yet to be done at all...
Source: Fight Aging! - January 5, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Better Characterizing the Clonal Expansion of Somatic Mutations in Aging Tissues
Mutational damage to nuclear DNA occurs constantly in all cells, and not all of it is successfully repaired. Setting aside recent evidence for cycles of damage and repair to cause epigenetic changes characteristic of aging, most unrepaired mutational damage has no meaningful consequence. It occurs in somatic cells that have few cell divisions left, so will not spread, and these cells will die or become senescent and be destroyed once they reach the Hayflick limit. It occurs in genes that are not active in the tissue in question, so even in long-lived somatic cells that do not replicate, such as those of the central nervous...
Source: Fight Aging! - January 2, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
A Look Back at 2019: Progress Towards the Treatment of Aging as a Medical Condition
Conclusion
A great deal of progress is being made in the matter of treating aging: in advocacy, in funding, in the research and development. It can never be enough, and it can never be fast enough, given the enormous cost in suffering and lost lives. The longevity industry is really only just getting started in the grand scheme of things: it looks vast to those of us who followed the slow, halting progress in aging research that was the state of things a decade or two ago. But it is still tiny compared to the rest of the medical industry, and it remains the case that there is a great deal of work yet to be done at all...
Source: Fight Aging! - December 31, 2019 Category: Research Authors: Reason Tags: Of Interest Source Type: blogs
Fight Aging! Newsletter, December 30th 2019
This study presents the effects of berberine (BBR) on the aging process resulting in a promising extension of lifespan in model organisms. BBR extended the replicative lifespan, improved the morphology, and boosted rejuvenation markers of replicative senescence in human fetal lung diploid fibroblasts. BBR also rescued senescent cells with late population doubling (PD). Furthermore, the senescence-associated β-galactosidase (SA-β-gal)-positive cell rates of late PD cells grown in the BBR-containing medium were ~72% lower than those of control cells, and its morphology resembled that of young cells. Mechanistically, BBR im...
Source: Fight Aging! - December 29, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Artificial Intelligence vs. Tuberculosis, Part 1
By SAURABH JHA, MD
Slumdog TB
No one knows who gave Rahul Roy
tuberculosis. Roy’s charmed life as a successful trader involved traveling in his
Mercedes C class between his apartment on the plush Nepean Sea Road in South
Mumbai and offices in Bombay Stock Exchange. He cared little for Mumbai’s weather.
He seldom rolled down his car windows – his ambient atmosphere, optimized for
his comfort, rarely changed.
Historically TB, or
“consumption” as it was known, was a Bohemian malady; the chronic suffering produced
a rhapsody which produced fine art. TB was fashionable in Victorian Britain, in
part, because c...
Source: The Health Care Blog - December 5, 2019 Category: Consumer Health News Authors: Christina Liu Tags: Artificial Intelligence Health Tech Saurabh Jha TB tuberculosis Source Type: blogs
Fight Aging! Newsletter, December 2nd 2019
In conclusion, T2D impairs vascular function by dysregulated autophagy. Therefore, autophagy could be a potential target for overcoming diabetic microvascular complications.
To What Degree Does Loss of Skeletal Muscle with Age Contribute to Immunosenescence?
https://www.fightaging.org/archives/2019/11/to-what-degree-does-loss-of-skeletal-muscle-with-age-contribute-to-immunosenescence/
Sarcopenia, the progressive loss of muscle mass and strength, is characteristic of aging. A perhaps surprisingly large fraction of the losses can be averted by strength training, but there are nonetheless inexorable proces...
Source: Fight Aging! - December 1, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, November 4th 2019
In this study, we hypothesized that moderately and chronically reducing ACh could attenuate the deleterious effects of aging on NMJs and skeletal muscles. To test this hypothesis, we analyzed NMJs and muscle fibers from heterozygous transgenic mice with reduced expression of the vesicular ACh transporter (VAChT), VKDHet mice, which present with approximately 30% less synaptic ACh compared to control mice.
Because ACh is constitutively decreased in VKDHet, we first analyzed developing NMJs and muscle fibers. We found no obvious morphological or molecular differences between NMJs and muscle fibers of VKDHet and contro...
Source: Fight Aging! - November 3, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Tiny Traps Lure Cancer Cells for Diagnostics, Treatment Monitoring
Detecting cancer at its early stages remains a major challenge in oncology. Even monitoring the progression of cancer is difficult, but researchers at the University of Michigan have come up with a tiny implantable device that can draw cancer cells toward itself for gene expression analysis.
The microscopic device is a biomaterial scaffold that is designed to allow new cells to settle within. Circulating tumor cells, being the most opportunistic at finding fresh nooks to make home, are quickly captured by the scaffold device.
Such implants can be positioned just under the skin in a simple procedure, and the presence ...
Source: Medgadget - October 30, 2019 Category: Medical Devices Authors: Medgadget Editors Tags: Materials Medicine Nanomedicine Oncology Source Type: blogs
Apps for Healthcare Monitoring: Interview with Artem Petrov, CEO of Reinvently
Reinvently, a mobile app development company based in Palo Alto, California, has created a number of healthcare apps, including those which collect, collate, and display data from wearable medical devices. The combination of a wearable device and a mobile app allows clinicians to monitor their patients in real-time and identify issues before they become a problem.
This approach is becoming increasingly popular, but in many cases, wearables are only as good as the software that accompanies them. Healthcare monitoring requires reliable and user-friendly apps that clearly display key data and alert users to issues as soon...
Source: Medgadget - September 25, 2019 Category: Medical Devices Authors: Conn Hastings Tags: Anesthesiology Cardiac Surgery Cardiology Critical Care Emergency Medicine Exclusive Vascular Surgery Source Type: blogs
From Brexit to TRexit: Transperineal biopsies pose a challenge to the traditional transrectal biopsy method
By now most of us are familiar with Brexit, the UK’s pending divorce with the European Union. But in a play on that term, British doctors are also moving towards an exit they’ve dubbed “TRexit” from the most common sort of prostate biopsy: the transrectal ultrasound guided biopsy, or TRUS.
Men who test positive on the PSA cancer screening test will usually have a prostate biopsy that’s performed in either of two ways. With a TRUS, doctors guided by an ultrasound machine can sample the prostate using a biopsy needle inserted through the rectum. Alternatively, the biopsy needle can be inserted (also under ultrasoun...
Source: Harvard Health Blog - July 26, 2019 Category: Consumer Health News Authors: Charlie Schmidt Tags: Diagnosis Prostate Knowledge HPK Source Type: blogs
Virtual Biopsy for Skin Lesions Using Vibrational Optical Coherence Tomography
Tissue biopsies of skin lesions can be unpleasant and quite painful. Moreover, a biopsy typically doesn’t sample the whole lesion and doesn’t provide much information about a given lesion’s size and depth. Now, scientists at Rutgers University have developed and tested a new device that relies on two different mechanisms to analyze skin lesions.
The new “virtual biopsy” device relies on vibrational optical coherence tomography to analyze tissue. It delivers pulses of near-infrared light, along with sound clicks, into the target tissue. The combination technology can identify how deep a lesion ...
Source: Medgadget - June 18, 2019 Category: Medical Devices Authors: Medgadget Editors Tags: Dermatology Oncology Pathology Source Type: blogs
