Screening flexible sigmoidoscopy versus colonoscopy for reduction of colorectal cancer mortality
ConclusionsScreening colonoscopy was associated with greater reductions in CRC mortality than screening sigmoidoscopy, and with a greater reduction in the distal than the proximal colon. These results provide additional information on the relative benefits of screening for CRC with sigmoidoscopy and colonoscopy. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - June 13, 2019 Category: Gastroenterology Source Type: research

Colorectal Cancer Screening in People With and Without HIV in an Integrated Health Care Setting
This study included PWH and demographically matched persons without HIV who were aged 50–75 years during 2005–2016 and had no previous CRC screening. We evaluated time to first CRC screening (fecal test, sigmoidoscopy, or colonoscopy). We also assessed detection of adenoma and CRC with sigmoidoscopy or colonoscopy by HIV status, accounting for CRC risk factors including sex, age, race/ethnicity, number of outpatient visits, smoking, body mass index, type-2 diabetes, and inflammatory bowel disease. Among PWH, we evaluated whether CD4 count ( (Source: JAIDS Journal of Acquired Immune Deficiency Syndromes)
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - June 13, 2019 Category: Infectious Diseases Tags: Epidemiology Source Type: research

Robotic transanal minimally invasive rectal mucosa harvest
ConclusionsTo our knowledge, this is the first use of R-TAMIS for rectal mucosa harvest. Our preliminary series indicates this approach is feasible and safe, constituting a promising minimally invasive technique for urethral reconstruction. Prospective studies evaluating graft outcomes and donor site morbidity with more long-term follow-up are needed. (Source: Surgical Endoscopy)
Source: Surgical Endoscopy - June 11, 2019 Category: Surgery Source Type: research

Appendicovesical fistula presenting as hypokalaemic hyperchloraemic metabolic acidosis: a case report.
Abstract A 52-year-old man was admitted with diarrhoea and faecaluria and referred recurrent urinary tract infections for over 20 years. He also reported a two-week hospital admission more than 20 years ago for right iliac fossa pain, which was managed conservatively. Computed tomography showed a fistulous tract extending from the bladder with an unclear connection to the bowel. Cystoscopy confirmed the presence of a vesical fistula and biopsy of the tract confirmed colonic mucosa. Flexible sigmoidoscopy was negative. A cystogram was requested as an outpatient procedure and the patient was discharged after antibio...
Source: Annals of the Royal College of Surgeons of England - June 3, 2019 Category: Surgery Authors: Keane S, Tebala GD Tags: Ann R Coll Surg Engl Source Type: research

Mo1062 AIR EMBOLISM AS A CONSEQUENCE OF ENDOSCOPY IN HOSPITALIZED PATIENTS: RESULTS FROM THE NATIONAL INPATIENT SAMPLE (1998-2013)
In this study, we aim to describe the national incidence and outcomes of air embolism following inpatient endoscopic procedures in the United States between 1998 and 2013. (Source: Gastrointestinal Endoscopy)
Source: Gastrointestinal Endoscopy - June 1, 2019 Category: Gastroenterology Authors: Babatunde Olaiya, Deola Saheed, Douglas G. Adler Tags: Monday abstract Source Type: research

[Rectal Ulcer Developed in Systemic Lupus Erythematosus without Ischemic Colitis].
Abstract Rectal involvement by systemic lupus erythematosus (SLE) is quite rare. Approximately 14 cases have been reported worldwide, but only one with ischemic colitis has been reported in Korea. A 17-year-old female patient was hospitalized with abdominal pain and hematochezia. Sigmoidoscopy revealed only a simple rectal ulcer without ischemic colitis. cytomegalovirus and bacterial infections were excluded. A sigmoidoscopic rectal biopsy indicated a rectal invasion by SLE, but the patient showed an acute worsening conditions that did not respond to treatment. This paper reports a case of rectal ulcer that develo...
Source: Korean J Gastroenter... - May 25, 2019 Category: Gastroenterology Authors: Sohn KC, Heo WG, Chu MS, Kim EJ, Chung JH, Choi SC, Yun KJ, Seo GS Tags: Korean J Gastroenterol Source Type: research

Oncologic Outcomes of Organ Preserving Approaches in Patients With Rectal Cancer Treated With Preoperative Chemoradiotherapy.
CONCLUSION: WW and LE were comparable in terms of 5-year OS and RFS. In the LE group, salvage treatment was performed much less among indicated patients. Therefore, methods to improve the oncologic outcomes of patients indicated for salvage treatment should be considered before local excision. PMID: 31113171 [PubMed] (Source: Annals of Coloproctology)
Source: Annals of Coloproctology - May 24, 2019 Category: Gastroenterology Tags: Ann Coloproctol Source Type: research

Effectiveness of sigmoidoscopy for assessing ulcerative colitis disease activity and therapeutic response
Ulcerative colitis (UC) typically begins in the rectum and progresses proximally in a contiguous fashion without skip lesions. Post-treatment inflammation distribution can change over time. Colonoscopy is unpleasant for the patient and clinical trials often use sigmoidoscopy for evaluation of disease severity. The aim of this study is to evaluate whether sigmoidoscopy is adequate to assess disease activity and therapeutic response as colonoscopy. We retrospectively reviewed patients who underwent colonoscopy for the initial diagnosis and follow-up by evaluating their mucosal inflammation in our hospital from January 2012 ...
Source: Medicine - May 1, 2019 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Management of acute sigmoid volvulus in a provincial centre-a 20-year experience.
CONCLUSION: Early sigmoid colectomy was associated with low morbidity and found to be safe in the elderly, and the results suggest that early surgery is associated with reduced readmissions and a low complication rate, with index surgery preferable to urgent elective surgery. Rigid sigmoidoscopy is a safe method of decompression as a bridge to index surgery and was not associated with any complications in this series. PMID: 30973858 [PubMed - in process] (Source: New Zealand Medical Journal)
Source: New Zealand Medical Journal - April 13, 2019 Category: General Medicine Tags: N Z Med J Source Type: research

Diagnosis and Treatment of Rectal Gastrointestinal Stromal Tumors
Case Summary: A 69-year-old man presented with a rectal mass that was noted on physical examination. Flexible sigmoidoscopy confirmed the presence of a well-defined mass 3 cm from the anal verge (Fig. 1). Magnetic resonance imaging of the pelvis identified a 5.8-cm heterogeneous mass with intersphincteric extension. Positron emission tomography-computed tomography revealed no evidence of distant metastatic disease. Endoscopic ultrasound (EUS) with fine-needle aspiration revealed a noncircumferential submucosal hypoechoic mass (Fig. 2) with pathology significant for spindle cells staining positive for CD117, consis...
Source: Diseases of the Colon and Rectum - April 10, 2019 Category: Gastroenterology Tags: Resident's Corner Source Type: research

Certification of UK gastrointestinal endoscopists and variations between trainee specialties: results from the JETS e-portfolio
Endosc Int Open 2019; 07: E551-E560 DOI: 10.1055/a-0839-4476 Introduction In the UK, endoscopy certification is administered by the Joint Advisory Group on Gastrointestinal Endoscopy (JAG). Since 2011, certification for upper and lower gastrointestinal endoscopy has been awarded via a national (JETS) e-portfolio to the main training specialties of: gastroenterology, gastrointestinal surgeons (GS) and non-medical endoscopists (NME). Trends in endoscopy certification and differences between trainee specialties were analyzed. Methods This prospective UK-wide observational study identified trainees awarded gast...
Source: Endoscopy International Open - April 4, 2019 Category: Gastroenterology Authors: Siau, Keith Anderson, John T. Valori, Roland Feeney, Mark Hawkes, Neil D. Johnson, Gavin McKaig, Brian C. Pullan, Rupert D. Hodson, James Wells, Christopher Thomas-Gibson, Siwan Haycock, Adam V. Beales, Ian L.P. Broughton, Raphael Dunckley, Paul Tags: Original article Source Type: research

Trends in colonoscopy and fecal occult blood test use after the introduction of dual screening offers in Germany: Results from a large population-based study, 2003–2016
Publication date: Available online 1 April 2019Source: Preventive MedicineAuthor(s): Chen Chen, Christian Stock, Lina Jansen, Jenny Chang-Claude, Michael Hoffmeister, Hermann BrennerAbstractAn increasing number of countries have recently introduced colorectal cancer (CRC) screening programs. Typically, one specific screening exam, such as fecal occult blood test (FOBT) or flexible sigmoidoscopy, is offered as a primary screening test. We aimed to assess trends in FOBT and colonoscopy use in Germany following the introduction of the offer of screening colonoscopy as an alternative to FOBT in 2002. We used data from 4052 con...
Source: Preventive Medicine - April 2, 2019 Category: International Medicine & Public Health Source Type: research

Early Endoscopy Is Associated with Better Clinical Outcomes in Patients Hospitalized with Ischemic Bowel Disease
ConclusionEarly endoscopy, especially colonoscopy, is associated with better clinical outcomes and decreased healthcare utilization in IB. Unfortunately, there are disparities against Blacks, and  non-privately insured individuals in receiving early endoscopy. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 30, 2019 Category: Gastroenterology Source Type: research

Oral Anticoagulants and Aspirin Use and Its Effect on Positive  Predictive Value of Fecal Immunochemical Test for Advanced Neoplasia in Colorectal Cancer Screening: To Bleed or Not to Bleed
Colorectal cancer (CRC) has a significant impact on public health owing to its high incidence, morbidity, and mortality.1 It is the third most common cancer in men and second in women, and in most countries the second leading cause of cancer-related death.1,2 The early detection and removal of precursor cancer lesions decreases CRC incidence and mortality. CRC screening has, therefore, been implemented in various countries worldwide.3 The selected modality varies per country or region and differs from primary colonoscopy, sigmoidoscopy to noninvasive testing, in particular by means of a fecal immunochemical test (FIT). (So...
Source: Gastroenterology - March 26, 2019 Category: Gastroenterology Authors: Manon C.W. Spaander, Ernst J. Kuipers Tags: Editorial Source Type: research

Effects of Oral Anticoagulant and Aspirin Use on Ability of Fecal Immunochemical Tests to Detect Advanced Neoplasia
Colorectal cancer (CRC) has a significant impact on public health owing to its high incidence, morbidity, and mortality.1 It is the third most common cancer in men and second in women, and in most countries the second leading cause of cancer-related death.1,2 The early detection and removal of precursor cancer lesions decreases CRC incidence and mortality. CRC screening has, therefore, been implemented in various countries worldwide.3 The selected modality varies per country or region and differs from primary colonoscopy, sigmoidoscopy to noninvasive testing, in particular by means of a fecal immunochemical test (FIT). (So...
Source: Gastroenterology - March 26, 2019 Category: Gastroenterology Authors: Manon C.W. Spaander, Ernst J. Kuipers Tags: Editorial Source Type: research

Need For Whole Large Bowel Investigation in Sole Change in Bowel Habit: An Analysis of 719 Patients.
CONCLUSIONS: Sole CIBH without anemia/abdominal mass yields a 2.5% colorectal malignancy rate from 2-week wait referrals. Those with PLS had a 0.17% yield of proximal tumors. A straight-to-test FS in this low risk group would be clinically effective with potential annual savings of more than £50 000. PMID: 30898041 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - March 23, 2019 Category: Surgery Tags: J Invest Surg Source Type: research

What Happened to Disparities in CRC Screening Among FFS Medicare Enrollees Following Medicare Modernization?
We examined Blacks, Asians, and Hispanics relative to Whites, and Females relative to Males (with race or ethnicity combined). We examined each state separately for evidence of disparities within states, to avoid confounding by geographic disparities. We expected that the net effect o f the policy changes and the targeted interventions over the decade would be to increase CRC screening by endoscopy, reducing disparities. We saw improvements over time (reduced disparities relative to Whites) for Blacks and Hispanics residing in several states, and improvements over time for Female s relative to Males in many states. For the...
Source: Journal of Racial and Ethnic Health Disparities - March 19, 2019 Category: International Medicine & Public Health Source Type: research

Safe investigation of isolated change in bowel habit with a flexible sigmoidoscopy? A systematic review and meta-analysis.
CONCLUSIONS: There is a higher than expected risk that if a cancer is diagnosed in a patient presenting with either an isolated change in bowel habit or a combination of change in bowel habit with rectal bleeding, the cancer may be right sided. PMID: 30855983 [PubMed - as supplied by publisher] (Source: Annals of the Royal College of Surgeons of England)
Source: Annals of the Royal College of Surgeons of England - March 11, 2019 Category: Surgery Authors: Herrod P, Boyd-Carson H, Doleman B, Blackwell J, Hardy E, Harper F, Lund JN Tags: Ann R Coll Surg Engl Source Type: research

Barriers and Facilitators of Colorectal Cancer Screening in a Federally Qualified Health Center (FQHC)
Conclusion: In this study, the most common perceived barriers to return of screening fecal test kits were forgetfulness and lack of motivation. The most common perceived facilitators were live call reminders and postage-paid return envelopes. Understanding barriers and facilitators to FITs may be necessary to enhance cancer screening rates in underserved patient populations. (Source: Journal of the American Board of Family Medicine)
Source: Journal of the American Board of Family Medicine - March 8, 2019 Category: Primary Care Authors: Ylitalo, K. R., Camp, B. G., Umstattd Meyer, M. R., Barron, L. A., Benavidez, G., Hess, B., Laschober, R., Griggs, J. O. Tags: Original Research Source Type: research

Flexible Sigmoidoscopy Rather than Colonoscopy Is Adequate for the Diagnosis of Ipilimumab-Associated Colitis.
CONCLUSIONS: Ipilimumab-associated colitis can be diagnosed with a flexible sigmoidoscopy alone, obviating the need for full colonoscopy. PMID: 30830228 [PubMed - in process] (Source: Southern Medical Journal)
Source: Southern Medical Journal - March 6, 2019 Category: General Medicine Tags: South Med J Source Type: research

The Value of Sigmoidoscopy to Detect Colonic Ischaemia After Ruptured Abdominal Aortic Aneurysm Repair
This study determined the diagnostic value of sigmoidoscopy in patients suspected of CI after RAAA repair. (Source: Journal of Vascular Surgery)
Source: Journal of Vascular Surgery - February 21, 2019 Category: Surgery Authors: H. Jalalzadeh, T.G. van Schaik, J.J. Duin, R. Indrakusuma, S.C. van Beek, A.C. Vahl, W. Wisselink, R. Balm, M.J.W. Koelemay Tags: Selected Abstract from the February Issue of the European Journal of Vascular and Endovascular Surgery Source Type: research

The Impacts of the ACA Medicaid Expansions on Cancer Screening Use by Primary Care Provider Supply
Conclusions: ACA Medicaid expansions were associated with increased cancer screening use only in states with high supply of primary care providers. Improving access for Medicaid beneficiaries in provider shortage areas may require coupling coverage expansions with supply-side interventions to increase provider availability. (Source: Medical Care)
Source: Medical Care - February 14, 2019 Category: Health Management Tags: Original Articles Source Type: research

Anastomotic Sinus That Developed From Leakage After a Rectal Cancer Resection: Should We Wait for Closure of the Stoma Until the Complete Resolution of the Sinus?
Conclusion: Patients with an anastomotic sinus who had been carefully selected underwent successful ileostomy closure without delay. PMID: 30727707 [PubMed - as supplied by publisher] (Source: Annals of Coloproctology)
Source: Annals of Coloproctology - February 9, 2019 Category: Gastroenterology Tags: Ann Coloproctol Source Type: research

[Acute Suppurative Appendicitis Diagnosed by Acute Lower Gastrointestinal Hemorrhage].
Abstract A 49-year-old man visited the emergency room of Korea University Ansan Hospital with hematochezia starting the day before the visit. Recently, he was on anti-platelet medication due to hypertension. The patient had no definite symptoms other than hematochezia. Digital rectal exam was positive and laboratory tests showed severe anemia. Sigmoidoscopy was initiated and almost no fecal material was observed in the intestinal tract, allowing insertion into the cecum. Active bleeding from the appendiceal opening was noted. On abdominal CT, contrast enhancement was observed at the tip of the appendix. Under susp...
Source: Korean J Gastroenter... - January 25, 2019 Category: Gastroenterology Authors: Kim DH, Lee JH, Kim D, Hwang S, Kang K, Koo JS Tags: Korean J Gastroenterol Source Type: research

Colon Cancer in Young Adults: Trends and Their Implications
We describe the epidemiologic shifts of CRC incidence and mortality across age groups as well as the differences in clinicopathologic, molecular, treatment, and survival characteristics between young and older patients. Novel studies of the microbiome may elucidate bacterial causes of CRC carcinogenesis in younger individuals. Moving up the colonoscopy screening to age 45 in normal-risk individuals should prove beneficial in detecting more patients with early-onset CRC.SummaryWe favor the development of risk-adaptive screening decision algorithms and flexible sigmoidoscopy screening at age 40 given the predilection for lef...
Source: Current Oncology Reports - January 18, 2019 Category: Cancer & Oncology Source Type: research

Cost-effectiveness of Colorectal Cancer Screening Strategies-a Systematic Review.
CONCLUSION: In an updated review, we found that common CRC screening strategies and computed tomographic colonography continued to be cost-effective compared to no screening. There were discrepancies among studies from different regions, which could be associated with the model types or model assumptions. PMID: 30659991 [PubMed - as supplied by publisher] (Source: Clinical Colorectal Cancer)
Source: Clinical Colorectal Cancer - January 16, 2019 Category: Cancer & Oncology Authors: Ran T, Cheng CY, Misselwitz B, Brenner H, Ubels J, Schlander M Tags: Clin Gastroenterol Hepatol Source Type: research

Prospective study on the safety and feasibility of early ileostomy closure 2 weeks after lower anterior resection for rectal cancer.
Conclusion: Transient loop ileostomy, which is confirmed to be intact endoscopically and radiologically, can be safely closed 2 weeks postoperatively without requiring a significant delay in adjuvant chemotherapy. PMID: 30603633 [PubMed] (Source: Annals of Surgical Treatment and Research)
Source: Annals of Surgical Treatment and Research - January 5, 2019 Category: Surgery Tags: Ann Surg Treat Res Source Type: research

Rapid review of factors associated with flexible sigmoidoscopy screening use
Publication date: Available online 28 December 2018Source: Preventive MedicineAuthor(s): Robert S. Kerrison, Christian von Wagner, Trish Green, Monica Winfield, Una Macleod, Mark Hughes, Colin J. Rees, Stephen Duffy, Lesley M. McGregorAbstractFlexible sigmoidoscopy (FS) screening has been shown to reduce colorectal cancer (CRC) incidence and mortality among screened adults. The aim of this review was to identify patient-related factors associated with the screening test's use.We searched PubMed for studies that examined the association between FS screening use and one or more factors. To determine the eligibility of studie...
Source: Preventive Medicine - December 28, 2018 Category: International Medicine & Public Health Source Type: research

Why Is Nonadherence to Cancer Screening Associated With Increased Mortality?
In this issue ofJAMA Internal Medicine, Pierre-Victor and Pinsky use data from the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening trial to demonstrate an association between lack of adherence to cancer screening and increased mortality from causes not related to the screening. Participants in the PLCO Cancer Screening trial were 55 to 74 years of age and generally healthy. At trial entry, participants of both sexes in the screening arm were asked to undergo chest radiographs for lung cancer and flexible sigmoidoscopy for colon cancer, men were asked to undergo prostate-specific antigen tests and digital rec...
Source: JAMA Internal Medicine - December 28, 2018 Category: Internal Medicine Source Type: research

Virtual reality simulation in endoscopy training: Current evidence and future directions.
Abstract Virtual reality simulation is becoming the standard when beginning endoscopic training. It offers various benefits including learning in a low-stakes environment, improvement of patient safety and optimization of valuable endoscopy time. This is a review of the evidence surrounding virtual reality simulation and its efficacy in teaching endoscopic techniques. There have been 21 randomized controlled trials (RCTs) that have investigated virtual reality simulation as a teaching tool in endoscopy. 10 RCTs studied virtual reality in colonoscopy, 3 in flexible sigmoidoscopy, 5 in esophagogastroduodenoscopy, an...
Source: World Journal of Gastroenterology - December 28, 2018 Category: Gastroenterology Authors: Mahmood T, Scaffidi MA, Khan R, Grover SC Tags: World J Gastroenterol Source Type: research

Transanal Tube Drainage as a Conservative Treatment for Anastomotic Leakage Following a Rectal Resection.
Conclusion: These results suggest that TD for management of patients with AL is safe, cheap, and effective. Salvaging the anastomosis will help decrease the need for Hartmann colostomy formation. Proper patient selection is important. PMID: 30572421 [PubMed - as supplied by publisher] (Source: Annals of Coloproctology)
Source: Annals of Coloproctology - December 24, 2018 Category: Gastroenterology Tags: Ann Coloproctol Source Type: research

Acceptability of receiving lifestyle advice at cervical, breast and bowel cancer screening
Publication date: Available online 19 December 2018Source: Preventive MedicineAuthor(s): Claire Stevens, Charlotte Vrinten, Samuel G. Smith, Jo Waller, Rebecca J. BeekenAbstractCancer screening could be an opportunity to deliver cancer prevention advice, but it is not known how such information would be received. We explored willingness to receive lifestyle advice in the context of the English National Health Service cervical, breast, and bowel (FS; flexible sigmoidoscopy) screening programmes. A population-based survey was conducted in 2016 to collect nationally representative data on willingness to receive lifestyle advi...
Source: Preventive Medicine - December 20, 2018 Category: International Medicine & Public Health Source Type: research

Whole-colon investigation vs. flexible sigmoidoscopy for suspected colorectal cancer based on presenting symptoms and signs: a multicentre cohort study
Whole-colon investigation vs. flexible sigmoidoscopy for suspected colorectal cancer based on presenting symptoms and signs: a multicentre cohort study, Published online: 19 December 2018; doi:10.1038/s41416-018-0335-zWhole-colon investigation vs. flexible sigmoidoscopy for suspected colorectal cancer based on presenting symptoms and signs: a multicentre cohort study (Source: British Journal of Cancer)
Source: British Journal of Cancer - December 19, 2018 Category: Cancer & Oncology Authors: Amanda J. Cross Kate Wooldrage Emma C. Robbins Kevin Pack Jeremy P. Brown William Hamilton Michael R. Thompson Karen G. Flashman Steve Halligan Siwan Thomas-Gibson Margaret Vance Brian P. Saunders Wendy Atkin Source Type: research

Compliance with Age-Appropriate Screening for Malignancies and Influenza Vaccination in 3-Year Lymphoma Survivors
Background: The frequency of preventive health practices (PHP), including age-appropriate screening for malignancies and immunizations, and compliance with PHP guidelines in lymphoma survivors is not known. We hypothesized that lymphoma survivors are more compliant with PHP than the general population but PHP rates may differ based on patient, disease and treatment characteristics.Methods: We identified eligible lymphoma patients from the SPORE Molecular Epidemiology Resource (MER) cohort, in which they were prospectively enrolled within 50 years and compliant if they had fecal occult blood test
Source: Blood - November 21, 2018 Category: Hematology Authors: Pophali, P., Larson, M. C., Allmer, C., Farooq, U., Link, B. K., Maurer, M. J., Cerhan, J. R., Thompson, C. A. Tags: 902. Health Services Research-Malignant Diseases: Poster III Source Type: research

The Role of Physician Recommendation in Colorectal Cancer Screening Receipt Among Immigrant Chinese Americans
AbstractChinese Americans have low colorectal cancer (CRC) screening rates. It is unclear whether physicians should offer all CRC screening modalities (fecal occult blood test [FOBT], sigmoidoscopy, colonoscopy) to Chinese Americans to increase screening. Seven hundred and twenty-five Chinese Americans were asked in a survey if their physician had ever recommended CRC screening and to self-report receipt and type of CRC screening. Participants whose physician had recommended all CRC screening modalities were significantly more likely to report ever having screening (adjusted odds ratio 4.29, 95% CI 1.26 –14.68) and b...
Source: Journal of Immigrant and Minority Health - November 19, 2018 Category: International Medicine & Public Health Source Type: research

Laparoscopic rectal tumor surgery after administration of a new sclerosing therapy (aluminum potassium sulfate and tannic acid injection) for internal hemorrhoids: A report of three cases
AbstractAluminum potassium sulfate and tannic acid (ALTA) injection is a new sclerosing therapy for internal hemorrhoids that has been gaining widespread use. However, there have been few reports about rectal cancer after ALTA injection. We performed laparoscopic surgery for three patients who had underwent ALTA therapy 6 months or 1 year earlier: (i) a 51 ‐year‐old man with neuroendocrine tumor; (ii) a 44‐year‐old woman with rectal cancer; and (iii) 77‐year‐old man with rectal cancer. All three patients had sclerosis of the resected rectal wall stump, making transection of the rectum difficult. Histological ex...
Source: Asian Journal of Endoscopic Surgery - November 8, 2018 Category: Surgery Authors: Saori Goto, Koya Hida, Nobuaki Hoshino, Shigeo Hisamori, Kenji Kawada, Takaki Sakurai, Yoshiharu Sakai Tags: Case Report Source Type: research

Long-Term Effectiveness of Sigmoidoscopy Screening in Women and Men.
r M, Hoff G PMID: 30398636 [PubMed - in process] (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - November 6, 2018 Category: Internal Medicine Authors: Holme Ø, Løberg M, Kalager M, Bretthauer M, Hoff G Tags: Ann Intern Med Source Type: research

Long-Term Effectiveness of Sigmoidoscopy Screening in Women and Men.
PMID: 30398635 [PubMed - in process] (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - November 6, 2018 Category: Internal Medicine Authors: Shaukat A, Church TR Tags: Ann Intern Med Source Type: research

Repeated rectal application of a hyperosmolar lubricant is associated with microbiota shifts but does not affect PrEP drug concentrations: results from a randomized trial in men who have sex with men.
CONCLUSIONS: Repeated rectal application of a hyperosmolar lubricant does not affect mucosal PrEP drug concentrations but is associated with changes in the rectal microbiome. PMID: 30378274 [PubMed - in process] (Source: Journal of the International AIDS Society)
Source: Journal of the International AIDS Society - November 2, 2018 Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research

Editor ’s Perspectives – November 2018
Rigid endoscopy started by designing rigid endoscopes which went through the natural orifices of the human body, e.g. proctoscopes or sigmoidoscopes through the anus, cystourethoscopes through the urethral orifice, laryngoscopes or oesophagoscopes through the mouth. Many of these scopes have gradually been replaced by flexible endoscopes which can go further into the human body along the lumens of the various organs. (Source: International Journal of Surgery)
Source: International Journal of Surgery - November 1, 2018 Category: Surgery Authors: Joseph W.Y. Lau Source Type: research

Preventing colorectal cancer or early diagnosis: Which is best? A re-analysis of the U.S. Preventive Services Task Force Evidence Report
Publication date: Available online 24 October 2018Source: Preventive MedicineAuthor(s): Andrew W. Swartz, Jan M. Eberth, Scott M. StrayerAbstractFlexible sigmoidoscopy (FS) is the only cancer screening test to lower the risk of death compared to usual care in randomized controlled trials (RCTs). We hypothesize that this unique death reduction is more attributable to prevention of colorectal cancer (CRC) than to early diagnosis. The systematic review of the 2016 US Preventive Services Task Force Evidence Report for CRC Screening was used for selection of RCT studies. A random-effects meta-analysis of five FS trials (N =...
Source: Preventive Medicine - October 24, 2018 Category: International Medicine & Public Health Source Type: research

Sigmoidoscopy an Effective Tool for Identifying Colonic Ischaemia After Ruptured AAA
The study by Jalalzadeh et  al.1 investigated the effectiveness of sigmoidoscopy for identifying colonic ischaemia (CI) in patients who suffered ruptured abdominal aortic aneurysms (RAAAs) in the Dutch Dream Trial. (Source: European Journal of Vascular and Endovascular Surgery)
Source: European Journal of Vascular and Endovascular Surgery - October 24, 2018 Category: Surgery Authors: Jonathan R. Boyle Tags: Invited Commentary Source Type: research

Differences in colorectal cancer screening rates across income strata by levels of urbanization: results from the Canadian Community Health Survey (2013/2014).
DISCUSSION: Half of Canadians report UTD-CRC screening but across levels of urbanization, higher income was associated with higher screening rates. Efforts are needed to understand and address inequities, particularly among low-income populations. PMID: 30353502 [PubMed - as supplied by publisher] (Source: Canadian Journal of Public Health)
Source: Canadian Journal of Public Health - October 23, 2018 Category: International Medicine & Public Health Authors: Simkin J, Ogilvie G, Hanley B, Elliott C Tags: Can J Public Health Source Type: research

Use of Two Self-referral Reminders and a Theory-Based Leaflet to Increase the Uptake of Flexible Sigmoidoscopy in the English Bowel Scope Screening Program: Results From a Randomized Controlled Trial in London.
This study reports the results following the second reminder. Methods: Men and women included in the initial sample (n = 1,383) were re-assessed for eligibility 24 months after their invitation (12 months after the first reminder) and excluded if they had attended screening, moved away, or died. Eligible adults received the same treatment they were allocated 12 months previous, that is, no reminder ("control"), or a self-referral reminder with either the standard information booklet ("Reminder and Standard Information Booklet") or theory-based leaflet designed using the Behavior Change Wheel ("...
Source: Annals of Behavioral Medicine - October 22, 2018 Category: Psychiatry & Psychology Authors: Kerrison RS, McGregor LM, Counsell N, Marshall S, Prentice A, Isitt J, Rees CJ, von Wagner C Tags: Ann Behav Med Source Type: research

Factors Influencing Colorectal Cancer Screening Among Thais in the U.S.
This study examined factors related to colorectal cancer (CRC) screening uptake among Thais in the United States. A total of 121 Thais between 50 and 75  years of age, who were married and living in southern California participated in the survey (mean age = 61 years). Out of all the participants, only 21% of the participants had fecal occult blood tests, 21% had sigmoidoscopy, and 45% had colonoscopy that were within the recommended period. Ov erall, 55% of participants met CRC screening adherence criteria. Participants who had had regular checkups in the previous 2 years without having any sym...
Source: Journal of Community Health - October 19, 2018 Category: International Medicine & Public Health Source Type: research

The Value of Sigmoidoscopy to Detect Colonic Ischaemia After Ruptured Abdominal Aortic Aneurysm Repair
This study determined the diagnostic value of sigmoidoscopy in patients suspected of CI after RAAA repair. (Source: European Journal of Vascular and Endovascular Surgery)
Source: European Journal of Vascular and Endovascular Surgery - October 11, 2018 Category: Surgery Authors: Hamid Jalalzadeh, Theodorus G. van Schaik, Jan J. Duin, Reza Indrakusuma, Sytse C. van Beek, Anco C. Vahl, Willem Wisselink, Ron Balm, Mark J.W. Koelemay Source Type: research

The Value of Sigmoidoscopy to Detect Colonic Ischaemia After Ruptured Abdominal Aortic Aneurysm Repair.
CONCLUSIONS: Sigmoidoscopy increases the likelihood of correctly identifying the presence or absence of transmural CI, especially in patients with a moderate clinical suspicion for CI after RAAA repair. PMID: 30318394 [PubMed - as supplied by publisher] (Source: PubMed: Eur J Vasc Endovasc ...)
Source: PubMed: Eur J Vasc Endovasc ... - October 11, 2018 Category: Surgery Authors: Jalalzadeh H, van Schaik TG, Duin JJ, Indrakusuma R, van Beek SC, Vahl AC, Wisselink W, Balm R, Koelemay MJW Tags: Eur J Vasc Endovasc Surg Source Type: research

Accuracy of pelvic MRI in measuring tumor height in rectal cancer patients with or without preoperative chemoradiotherapy
Publication date: Available online 9 October 2018Source: European Journal of Surgical OncologyAuthor(s): Eric Chung, Dongwon Kang, Hye Sun Lee, Eun-Suk Cho, Joo Hee Kim, Eun Jung Park, Seung Hyuk Baik, Kang Young Lee, Jeonghyun KangAbstractIntroductionIn measuring tumor height for rectal cancer, rigid sigmoidoscopy (RS) is a standard modality, and the accuracy of magnetic resonance imaging(MRI) in patients with/without preoperative chemoradiotherapy (CRT) has not been fully investigated. The aim of this study was to investigate the accuracy of MRI for measuring tumor height.Materials and MethodsAmong rectal cancer patients...
Source: European Journal of Surgical Oncology (EJSO) - October 10, 2018 Category: Surgery Source Type: research

Barriers to bowel scope (flexible sigmoidoscopy) screening: a comparison of non-responders, active decliners and non-attenders
This study aimed to quantify the prevalence of barriers to BSS and e... (Source: BMC Public Health)
Source: BMC Public Health - October 5, 2018 Category: Consumer Health News Authors: Christian von Wagner, Bernardette Bonello, Sandro Stoffel, Hanna Skrobanski, Madeleine Freeman, Robert S Kerrison and Lesley M McGregor Tags: Research article Source Type: research

Recommendations on prevention and screening for colorectal cancer in Hong Kong.
Abstract Colorectal cancer is the commonest cancer in Hong Kong. The Cancer Expert Working Group on Cancer Prevention and Screening was established in 2002 under the Cancer Coordinating Committee to review local and international scientific evidence, assess and formulate local recommendations on cancer prevention and screening. At present, the Cancer Expert Working Group recommends that average-risk individuals aged 50 to 75 years and without significant family history consult their doctors to consider screening by: (1) annual or biennial faecal occult blood test, (2) sigmoidoscopy every 5 years, or (3) colonoscop...
Source: Hong Kong Med J - October 1, 2018 Category: General Medicine Authors: Lam TH, Wong KH, Chan KK, Chan MC, Chao DV, Cheung AN, Fan CY, Ho J, Hui EP, Lam KO, Law CK, Law WL, Loong HH, Ngan RK, Tsang TH, Wong MC, Yeung RM, Ying AC, Ching R Tags: Hong Kong Med J Source Type: research