PicnicHealth Raises a $60m Series C to Expand Patient-centered Real-world Data
PicnicHealth, a patient-centered health technology company, today announced the closing of a $60 million Series C financing led by new investor B Capital Group. Existing investors Felicis Ventures and Amplify Partners also joined the round, bringing the total PicnicHealth has raised to more than $100 million. The company also announced plans to build 30 new patient-centered real-world data cohorts, and the addition of Adam Seabrook, Partner at B Capital Group, to the PicnicHealth board of directors. PicnicHealth takes a patient-centered approach to building deep real-world datasets for life sciences researchers. This compl...
Source: EMR and HIPAA - July 1, 2022 Category: Information Technology Authors: Healthcare IT News Tags: Analytics/Big Data Health IT Company Healthcare IT Adam Seabrook Amplify Partner B Capital Group Felicis Ventures Health IT Funding Health IT Fundings Health IT Investment Noga Leviner PicnicHealth Real-World Data Robert Mittendo Source Type: blogs

Hunting Disease-Causing Genetic Variants
Dr. Miriam Meisler. Credit: University of Michigan Medical School. “In my lab, we’ve been gene hunters—starting with visible phenotypes, or characteristics, and searching for the responsible genes,” says Miriam Meisler, Ph.D., the Myron Levine Distinguished University Professor at the University of Michigan Medical School in Ann Arbor. During her career, Dr. Meisler has identified the functions of multiple genes and has shown how genetic variants, or mutations, can impact human health. Becoming a Scientist Dr. Meisler had a strong interest in science as a child, which she credits to “growing up at the tim...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - June 29, 2022 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Genes Injury and Illness Diseases DNA Profiles Research Organisms Scientific Process Source Type: blogs

Empowering Trainees to be Leaders and Change Agents
We described several wellness initiatives that were done at individual campuses. The University of Illinois where I attend, we had a wellness committee that we formed led by students. We were able to partner with local companies to bring in more healthy food options. We were able to set up a counseling center dedicated specifically towards medical trainees. Joe Geraghty: And so that’s at the institutional level, but then in our local community, we had several letters from places like the University of Chicago. We had a medical student who wrote about how they were developing kind of like easy to digest infograp...
Source: Academic Medicine Blog - April 25, 2022 Category: Universities & Medical Training Authors: amrounds Tags: AM Podcast AM Podcast Transcript Annual Call for Trainee-Authored Letters to the Editor ATLAS Trainee Perspective leadership medical education scholarship medical students residents scholarly publishing trainee engagement Source Type: blogs

The connection between sickle cell disease and socioeconomics
Two new treatments have emerged for sickle cell disease. One curative treatment is a bone marrow transplant, and the second treatment is a gene-based therapy undergoing clinical trials. While this is much-welcomed news for patients battling the disease, the medical profession still needs to address sickle cell disease’s socioeconomic and racial health care inequities. SickleRead more …The connection between sickle cell disease and socioeconomics originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - April 8, 2022 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/post-author/ramandeep-kaur" rel="tag" > Ramandeep Kaur, MD < /a > < /span > Tags: Physician Oncology/Hematology Public Health & Policy Source Type: blogs

Patients need palliative care to manage the pain of sickle cell disease [PODCAST]
“Sickle cell disease (SCD) affects about 100,000 Americans as an inherited genetic disorder with intermittent exacerbations requiring hospitalization. SCD is also a painful and complicated disease with no single physician specialist that can provide pain relief. While SCD pain is similar in severity to cancer pain, patients struggle to find adequate pain relief because theyRead more …Patients need palliative care to manage the pain of sickle cell disease [PODCAST] originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 25, 2022 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/post-author/the-podcast-by-kevinmd" rel="tag" > The Podcast by KevinMD < /a > < /span > Tags: Podcast Oncology/Hematology Source Type: blogs

Patients need palliative care to manage the pain of sickle cell disease
Sickle cell disease (SCD) affects about 100,000 Americans as an inherited genetic disorder with intermittent exacerbations requiring hospitalization. SCD is also a painful and complicated disease with no single physician specialist that can provide pain relief. While SCD pain is similar in severity to cancer pain, patients struggle to find adequate pain relief because theyRead more …Patients need palliative care to manage the pain of sickle cell disease originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - February 4, 2022 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/ramandeep-kaur" rel="tag" > Ramandeep Kaur, MD < /a > < /span > Tags: Conditions Oncology/Hematology Source Type: blogs

No one ’s listening: an inquiry into the avoidable deaths and failures of care for sickle cell patients in secondary care
This report, jointly published with the Sickle Cell Society, has found “serious care failings” in acute services and evidence of attitudes underpinned by racism. These concerns have led to a fear and avoidance of hospitals for many people living with sickle cell. The report includes a number of recommendations and the APPG is calling on the Secretary of State for H ealth and Social Care, NHS England and NHS Improvement to prioritise taking urgent action. ReportPress release (Source: Health Management Specialist Library)
Source: Health Management Specialist Library - November 15, 2021 Category: UK Health Authors: The King ' s Fund Library Tags: Public health and health inequalities Quality of care and clinical outcomes Source Type: blogs

Sickle cell disease in newborns and children: What families should know and do
If you’ve learned that your newborn or young child has sickle cell disease, you — and other family members and friends — may have many questions. These days, most cases of sickle cell disease in the US are diagnosed through newborn screening. It’s important to make the diagnosis early, so that babies can be started on penicillin (or another antibiotic) to prevent infection. Getting connected early to a pediatrician for primary care — and to specialists in blood disorders who can work closely with the child as they grow, and with their families — can help prevent complications of the disease. The basics Hemoglob...
Source: Harvard Health Blog - May 6, 2021 Category: Consumer Health News Authors: Claire McCarthy, MD Tags: Children's Health Genes Health care disparities Parenting Source Type: blogs

Fully vaccinated against COVID-19? So, what can you safely do?
Congrats on getting your COVID-19 vaccine! You qualify as fully vaccinated two weeks after your second dose of the Moderna or Pfizer/BioNTech vaccine, or two weeks after your single dose of the Johnson & Johnson vaccine, according to the US Centers for Disease Control and Prevention (CDC). Maybe you’re wondering what you can safely do now that you’re fully vaccinated. As an infectious disease specialist, I’ve provided answers to some common questions. Please keep in mind that information about COVID-19 and vaccines is evolving, and recommendations may change as we learn more. Can I gather with people outside my h...
Source: Harvard Health Blog - March 25, 2021 Category: Consumer Health News Authors: Amy C. Sherman, MD Tags: Coronavirus and COVID-19 Health Parenting Relationships Vaccines Source Type: blogs

What ’s behind racial disparities in kidney disease?
My first exposure to kidney disease and its impact on communities of color occurred when I was in high school. An elderly neighbor, who was like a grandfather to me, had been diagnosed with kidney failure. At about the same time, my older first cousin, who had children about my age, was starting dialysis due to kidney failure attributed to hypertension. She would go on to get a kidney transplant. If you ask any African American, he or she is likely to have at least one relative with kidney disease requiring dialysis or transplantation. Disparities in kidney disease not noted in medical literature until early 1980s When I b...
Source: Harvard Health Blog - February 3, 2021 Category: Consumer Health News Authors: J. Kevin Tucker, MD Tags: Health care disparities Kidney and urinary tract Source Type: blogs

Refusal Redux. Revisiting Debate About Adolescent Refusal of Treatment.
by Prof Dominic Wilkinson @Neonatalethics Last month, in an emergency hearing, the High court in London heard a case that characterises a familiar problem in medical ethics. A 15 year old adolescent (known as ‘X’) with a long-standing medical condition, Sickle Cell disease, had a very low blood count and required an urgent blood transfusion. […] (Source: blog.bioethics.net)
Source: blog.bioethics.net - November 25, 2020 Category: Medical Ethics Authors: Dominic Wilkinson Tags: Clinical Ethics Health Care bioethics Children and Families Dominic Wilkinson's Posts Euthanasia and Assisted Suicide syndicated Source Type: blogs

Q & A With Nobel Laureate and CRISPR Scientist Jennifer Doudna
Jennifer Doudna, Ph.D. Credit: University of California, Berkeley. The 2020 Nobel Prize in Chemistry was awarded to Jennifer Doudna, Ph.D., and Emmanuelle Charpentier, Ph.D., for the development of the gene-editing tool CRISPR. Dr. Doudna shared her thoughts on the award and answered questions about CRISPR in a live chat with NIH Director Francis S. Collins, M.D., Ph.D. Here are a few highlights from the interview. Q: How did you find out that you won the Nobel Prize? A: It’s a little bit of an embarrassing story. I slept through a very important phone call and finally woke up when a reporter called me. I was just comin...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - November 18, 2020 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Genes Tools and Techniques Cool Tools/Techniques CRISPR DNA Gene Editing Nobel Prize Source Type: blogs

Ultrasound Device to Rapidly Diagnose Sickle Cell Disease
Researchers at the University of Colorado have developed a new rapid test for sickle cell disease. Their tiny device is less than the size of a quarter, and can provide a result in as little as one minute. The technology uses ultrasound to heat a protein sample and then measures how it dissolves over time to identify the protein responsible for sickle cell disease. Relatively inexpensive and requiring only a simple camera (such as those on a smartphone), a power source and a microscope, the technology could be suitable for use in low-resource regions. “In Africa, sickle cell disease is the cause of death in 5% of ...
Source: Medgadget - October 16, 2020 Category: Medical Devices Authors: Conn Hastings Tags: Diagnostics Medicine Public Health Source Type: blogs

CXR Case 158
Michael A. Gibbs, MD CXR Case 158 25 year old with a history of sickle cell disease presents with severe back and bilateral leg pain. Describe and interpret the progression of her CXR's (Source: Life in the Fast Lane)
Source: Life in the Fast Lane - April 16, 2020 Category: Emergency Medicine Authors: Michael A. Gibbs, MD Tags: Radiology acute chest syndrome CXR CXR interpretation CXR Quiz Sickle Cell Sickle Cell Crisis sickle cell disease Source Type: blogs

Fight Aging! Newsletter, April 13th 2020
This study is par for the course, looking at Japanese Olympic participants. Interestingly, it hints at the upper end of the dose-response curve for physical activity, in that a longer career as a professional athlete may be detrimental in comparison to lesser degrees of exercise and training. From this large, retrospective cohort study targeting 3546 Japanese Olympic athletes, we observed significant lower mortality among Olympians compared with the Japanese general population. The overall standardised mortality ratio (SMR) was 0.29. The results were consistent with previous studies conducted in other non-Asian co...
Source: Fight Aging! - April 12, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs