Diffuse ST depression, and ST elevation in aVR. Left main, right?
This ECG was recorded on a middle-aged male with sickle cell disease and diffuse pain.Sinus rhythmLeft ventricular hypertrophy (LVH)Diffuse significant ST depression with ST Elevation in aVRComputerized QT = 494 ms, QTc = 538 msWhat else?What do you think?Here is a Previous ECG for comparison:Baseline LVHOnly minimal ST depressionDiffuse ST depression with ST Elevation in aVRKnotts et al. found that such ECG findings only represented left main ACS in 14% of such ECGs: Only 23% of patients with the aVR STE pattern had any LM disease (fewer if defined as ≥ 50% stenosis). Only 28% of patients had ACS of...
Source: Dr. Smith's ECG Blog - March 1, 2019 Category: Cardiology Authors: Steve Smith Source Type: blogs
Designer Babies: A Dystopian Sidetrack of Gene Editing
A Chinese scientist shocked the scientific community a couple of days ago with the announcement of having modified the very blueprint of life. If his claims are true, he tried to bestow two baby girls the ability to resist possible future infections with HIV. The outrage shows that humanity is not prepared to utilize the power of gene editing on embryos yet. We have no idea about the biological consequences, and we haven’t tackled the necessary legal and ethical issues.
Genes to become toys of the “Gods”?
Humanity has come a long way since Aldous Huxley pinned down how methods of genetic engineering, biological cond...
Source: The Medical Futurist - December 15, 2018 Category: Information Technology Authors: nora Tags: Bioethics Future of Medicine Genomics designer babies designer baby Gene gene editing genes Genome genome sequencing Health Healthcare healthcare system Innovation technology Source Type: blogs
Sickle cell is my neighbor
I was diagnosed with sickle cell disease at three months old in Haiti. The diagnosis from the doctor was followed by more tragic news; my parents were told that I was not going to live past five months. From that point on, my parents searched high and low for medication and knowledge about this unfamiliar […]Find jobs at Careers by KevinMD.com. Search thousands of physician, PA, NP, and CRNA jobs now. Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - December 6, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/benjedick-joseph-and-amy-sobota" rel="tag" > Benjedick Joseph, RN and Amy Sobota, MD, MPH < /a > Tags: Conditions Oncology/Hematology Source Type: blogs
How sickle cell anemia influences a medical school journey
“Where there is no struggle, there is no compassion.” -Frederick Douglass Growing up with sickle cell anemia exposed me to the field of medicine. As I go through the pain and complications, it humbles me to the point that motivates me to work harder to be the doctor I want for myself. I want to […]Find jobs at Careers by KevinMD.com. Search thousands of physician, PA, NP, and CRNA jobs now. Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - November 26, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/bianca-bowden" rel="tag" > Bianca Bowden < /a > Tags: Education Medical school Oncology/Hematology Source Type: blogs
I Got My Whole Genome Sequenced. Here ’s What I Learned.
Dante Labs sent me their Full DNA whole genome sequencing package, and I went through a roller-coaster of feelings: I was excited to know every secret of my cells, but I was afraid to get to know my hereditary cancer risks and worried what I might find. As in my case, (scientific) curiosity usually overrides fear, I jumped into the unknown and I’m eager to share my results here.
Whole genome sequencing is available to anyone. So what?
The human genome is the blueprint for building a person. When the Human Genome Project was completed in 2006, and the DNA double spiral uncovered its secrets for the very first time, scient...
Source: The Medical Futurist - November 20, 2018 Category: Information Technology Authors: nora Tags: Biotechnology Genomics Medical Professionals Patients Personalized Medicine Policy Makers Dante Labs data DNA future genetic genome sequencing genomic data genomic testing Health health risks health science Healthcare I Source Type: blogs
Mandated Queries of the Florida Prescription Drug Monitoring Program: Early Experiences from a Cancer Center-based Outpatient Palliative Medicine Clinic
This article describes our e xperiences in the first month of experience with the new law, although we plan to examine queries for a total of three months before closing this QI project.For the purpose of this QI project, we have documented patients ’ demographics, including each patient’s age, gender and limited identifying information, such as patient names and identification numbers; this data will be de-identified for any statistical analysis planned in the future. We also recorded patients’ main diagnosis and pain symptoms, the numbe r of prescribers listed by the PDMP as well as the dose of the patient’s opio...
Source: Pallimed: A Hospice and Palliative Medicine Blog - September 14, 2018 Category: Palliative Care Tags: kollas opioids pdmp quality improvement The profession Source Type: blogs
With every hardship comes ease
“Where is my baby?” I awoke upset that my belly, which hours before was bulging through my doctor scrubs, had surprisingly been flattened. No one had asked for my permission to deliver my baby. They told me he was delivered emergently — at 32-weeks gestation — to save both our lives.
I was a third-year pediatric resident, the senior for the pediatric ICU, on the night of my son’s birth. My overnight call had just started with an admission of a 12-year-old in pain of a sickle cell crisis. As I began writing up the admitting orders, I felt a sudden descent in my pregnant belly, and then an intense, halting stab of ...
Source: Kevin, M.D. - Medical Weblog - September 12, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/alya-ahmad" rel="tag" > Alya Ahmad, MD < /a > Tags: Physician Critical Care Pediatrics Source Type: blogs
Believe Me When I Say That I ’m In Pain
A young man with SCD presents to the ED reporting that his leg and back pain is a 9 on a 10-point scale. “Really?” The nurse responds in disbelief—he is not grimacing, sweating, or crying out in pain. One of the first things that nurses learn about pain is that “pain is whatever the person
The post Believe Me When I Say That I’m In Pain appeared first on Johns Hopkins Nursing Magazine. (Source: Nursing Blogs at Johns Hopkins University)
Source: Nursing Blogs at Johns Hopkins University - September 7, 2018 Category: Nursing Authors: Editor Tags: Health Equity On the Pulse pain sickle cell disease Source Type: blogs
Cord Blood and Your Family ’s Future
Storing your child’s cord blood is an incredible way to invest in their future health and well-being. What you might not know: The same cord blood can be used to cure devastating diseases in your other children, or even in you. Click here to read the story of Hamad, a young Emirati boy who was cured of sickle cell anemia. He wasn’t cured with his own cord blood; he was cured with cord blood stem cells from his younger brother. Cord blood isn’t just an investment in your child; it’s an investment in your family.
Call us to learn more about cord blood and cord blood tissue banking.
The post Cord Blood and Your Fami...
Source: Cord Blood News - August 20, 2018 Category: Perinatology & Neonatology Authors: maze_cordadmin Tags: Cord Blood Cord Tissue parents Source Type: blogs
LITFL Review 341
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog
Welcome to the 341st LITFL Review! Your regular and reliable source for the highest highlights, sneakiest sneak peeks and loudest shout-outs from the webbed world of emergency medicine and critical care. Each week the LITFL team casts the spotlight on the blogosphere’s best and brightest and deliver a bite-sized chunk of FOAM.
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The Most Fair Dinkum Ripper Beauts of the Week
PARAMEDIC-2 epi...
Source: Life in the Fast Lane - July 22, 2018 Category: Emergency Medicine Authors: Marjorie Lazoff, MD Tags: LITFL review LITFL R/V Source Type: blogs
What counts as " memory " and who gets to define it?
Do Plants Have “Memory”?A new paper byB édécarrats et al. (2018) is the latest entry into the iconoclastic hullabaloo claiming a non-synaptic basis for learning and memory. In short, “RNA extracted from the central nervous system ofAplysia given long-term sensitization training induced sensitization when injected into untrained animals... ” The results support the minority view that long-term memory is not encoded by synaptic strength, according to the authors, but instead by molecules inside cells (à laRandy Gallistel).Adam Calhoun has a nice summary of the paper atNeuroecology:...there is a particularreflex1(m...
Source: The Neurocritic - May 21, 2018 Category: Neuroscience Authors: The Neurocritic Source Type: blogs
Notice of Funding Opportunity: Bioethics and Disability
This report would examine developments at the state and federal-level, court cases, and current views from stakeholders.
Policy Questions
Which states have PAS laws and what do those laws provide? What protections against abuse of PAS?What have the Supreme Court and lower courts held regarding individuals’ rights under PAS laws? The laws themselves?Is there evidence that persons with disabilities are being denied treatment by insurance companies but offered PAS instead, as NCD predicted?How is PAS viewed by disability organizations? Has this evolved in the past 13 years? If so why? If not, why?Are persons with disabi...
Source: blog.bioethics.net - May 8, 2018 Category: Medical Ethics Authors: Thaddeus Mason Pope, JD, PhD Tags: Health Care syndicated Source Type: blogs
New treatment through stem cell transplant for Sickle cell anemia
Sickle cell anemia is a form of anemia in which there aren’t enough healthy red blood cells to carry enough oxygen throughout your body. General symptoms include fatigue and joint pain with periods of intense pain that can last either hours or weeks.
Revee Agyepong, a 17-year-old from Edmonton, Canada, suffered from sickle cell anemia with symptoms of chronic bone and joint pain, irregular heartbeat, kidney stones and shortness of breath.
“I thought that everyone would go out for recess and play, then come back with a terrible headache and body pain, couldn’t breathe … eventually I realized it was j...
Source: Cord Blood News - April 30, 2018 Category: Perinatology & Neonatology Authors: Maze Cord Blood Tags: blood disorder Cord Blood medical research stem cells Source Type: blogs
