Adoptive T-cell therapy ADP-A2M4 targeting MAGE-A4 shows early activity in patients with advanced solid tumors
(University of Texas M. D. Anderson Cancer Center) The adoptive T-cell therapy ADP-A2M4, which is engineered to express a T-cell receptor (TCR) directed against the MAGE-A4 cancer antigen, achieved responses in patients with multiple solid tumor types, including synovial sarcoma, head and neck cancer and lung cancer, according to results from a Phase I clinical trial led by researchers at The University of Texas MD Anderson Cancer Center. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 29, 2020 Category: International Medicine & Public Health Source Type: news

FDA Approves Pomalidomide for Kaposi Sarcoma FDA Approves Pomalidomide for Kaposi Sarcoma
Pomalidomide is the first new treatment option for Kaposi sarcoma in more than 20 years; the drug is already marketed for multiple myeloma.FDA Approvals (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - May 15, 2020 Category: Cancer & Oncology Tags: Hematology-Oncology News Alert Source Type: news

FDA Approves Pomalidomide for Patients with AIDS-Related Kaposi Sarcoma
Pomalidomide was approved for patients with AIDS-related Kaposi sarcoma whose disease has become resistant to highly active antiretroviral therapy, or in patients with Kaposi sarcoma who are HIV-negative. (Source: CancerNetwork)
Source: CancerNetwork - May 15, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

U.S. Food and Drug Administration Approves Bristol Myers Squibb ’s Pomalyst (pomalidomide) for AIDS-Related and HIV-Negative Kaposi Sarcoma
PRINCETON, N.J.--(BUSINESS WIRE)--May 15, 2020 -- Bristol Myers Squibb (NYSE: BMY) today announced that Pomalyst® (pomalidomide) was approved by the U.S. Food and Drug Administration (FDA) for patients with AIDS-related Kaposi sarcoma whose... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - May 15, 2020 Category: Drugs & Pharmacology Source Type: news

E-scooter  - a new source of danger in tumor endoprosthetics - den Toom DA, Bockholt S, Gosheger G, Budny T, Deventer N, Lübben T, Schneider KN.
A  24-year-old male patient who suffered a periprosthetic fracture of the left distal femur due to an e‑scooter accident was referred to the outpatient department of tumor orthopedics. The patient had been diagnosed with Ewing's sarcoma of the left prox... (Source: SafetyLit)
Source: SafetyLit - March 25, 2020 Category: International Medicine & Public Health Tags: Engineering, Physics, Structural Soundness and Failure Source Type: news

Incidence and risk factors for suicide death among Kaposi's sarcoma patients: a surveillance, epidemiology, and end results analysis - Shen J, Zhu M, Li S, Wang Q, Wu J, Li Y, Wang Q, Bian X, Yang L, Jiang X, Xie J, Lu Y, Wang K, Li L.
BACKGROUND The suicide risk of patients with cancer is higher than the general population. Our research aimed to explore the Surveillance, Epidemiology, and End Results (SEER) database to define incidence and quest risk factors for death of suicide in pati... (Source: SafetyLit)
Source: SafetyLit - March 12, 2020 Category: International Medicine & Public Health Tags: Research Methods, Surveillance and Codes, Models Source Type: news

Sarcoma Surveillance: A Review of Evidence and Guidelines Sarcoma Surveillance: A Review of Evidence and Guidelines
When it comes to surveillance strategies for sarcoma, what do existing guidelines and evidence recommend?Journal of the American Academy of Orthopaedic Surgeons (Source: Medscape Orthopaedics Headlines)
Source: Medscape Orthopaedics Headlines - February 19, 2020 Category: Orthopaedics Tags: Orthopaedics Journal Article Source Type: news

Uganda: Ministry of Health Moves to Regulate Cancer Homes as Residents Turn Into Beggars
[Independent (Kampala)] Kampala -Agnes Emujong battles Kaposi's sarcoma, a type of cancer that usually affects people living with HIV. The disease has made her develop large protruding tumors on the nose and eye areas that have almost shrunk her face. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - February 19, 2020 Category: African Health Source Type: news

Mother could give birth to her own GRANDCHILD
Jasmine Bowley, 21, from Norwich, had her ovaries and Fallopian tubes removed when she developed pelvic Ewing's sarcoma aged seven - which also affected her womb. (Source: the Mail online | Health)
Source: the Mail online | Health - February 18, 2020 Category: Consumer Health News Source Type: news

Much shorter radiation treatment found to be safe, effective for people with soft tissue sarcoma
In this study at UCLA, a national leader in the care of patients with sarcoma, researchers used a condensed five-day radiation regimen that considerably cuts down the length of treatment and the time to surgery.“Shortening the radiation therapy from five weeks to five days has been a very meaningful change for patients,” said lead author Dr. Anusha Kalbasi, assistant professor of radiation oncology in the division of molecular and cellular oncology. “Five weeks of daily treatments is a burdensome com mitment for patients. The daily back-and-forth can be expensive and time consuming, and it can really interfere with w...
Source: UCLA Newsroom: Health Sciences - February 13, 2020 Category: Universities & Medical Training Source Type: news

Much shorter radiation treatment found to be safe, effective for people with soft tissue sarcoma
(University of California - Los Angeles Health Sciences) A new study led by researchers at UCLA found that treating soft tissue sarcoma with radiation over a significantly shorter period of time is safe, and likely just as effective, as a much longer conventional course of treatment. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 13, 2020 Category: Cancer & Oncology Source Type: news

UN Health Agency Predicts 80 Percent Rise in Cancer Burden Among Poorest Countries
Many specialist doctors and nurses in Africa are migrating to greener pastures, leaving cancer patients with few options. Credit: Jeffrey Moyo/IPSBy External SourceLONDON, Feb 7 2020 (IPS) Low- and middle-income countries could see an 80 per cent rise in cancer over the next 20 years if treatment and prevention services are not stepped up, according to the latest World Cancer Report. The report, compiled by the World Health Organization (WHO), warns that cancer prevention is taking a back seat in poor countries, as their health systems tackle such immediate problems as infectious diseases, child health and nutrition. The r...
Source: IPS Inter Press Service - Health - February 7, 2020 Category: International Medicine & Public Health Authors: External Source Tags: Global Headlines Health Poverty & SDGs Source Type: news

St. Jude's scientist receives ACGT grant for sarcoma gene therapy
(Alliance for Cancer Gene Therapy) Stephen Gottschalk, MD, of St. Jude Children's Research Hospital receives $500k grant to use genetically engineered immune cells to attack pediatric sarcoma. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 7, 2020 Category: Cancer & Oncology Source Type: news

Drug Trials Snapshots: TAZVERIK
TAZVERIK is a drug used to treat a type of cancer called advanced epithelioid sarcoma. It is to be used in patients 16 years and older when cancer has spread and cannot be completely removed by surgery. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 4, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news