Tu1549 INTRATUMORAL SALMONELLA ABUNDANCE IN HEPATOCELLULAR CARCINOMA IS ASSOCIATED WITH INCREASED DENDRITIC CELL INFILTRATE AND IMPROVED SURVIVAL OUTCOMES
(Source: Gastroenterology)
Source: Gastroenterology - May 6, 2024 Category: Gastroenterology Authors: Mohammed Al-Zakwani, Alam Merchant, Daniel T. Segarra, Saif Zaman Tags: AASLD Abstracts Source Type: research
A Food Poisoning Caused by Salmonella Enterica (S. Enteritidis) ST11 Carrying Multi-Antimicrobial Resistance Genes in 2019, China
(Source: Infection and Drug Resistance)
Source: Infection and Drug Resistance - May 6, 2024 Category: Infectious Diseases Tags: Infection and Drug Resistance Source Type: research
Treatment of cholangiocarcinoma by pGCsiRNA-vascular endothelial growth factor in vivo
CONCLUSIONS: In vivo silencing of VEGF can affect cell survival and inhibit cell migration, invasion, and development, probably by enhancing apoptosis and inhibiting the expressions of MMP2 and MMP9.PMID:38708333 | PMC:PMC11063079 | DOI:10.2478/abm-2024-0009 (Source: Cell Research)
Source: Cell Research - May 6, 2024 Category: Cytology Authors: Shenglin Lu Jun Li Source Type: research
Treatment of cholangiocarcinoma by pGCsiRNA-vascular endothelial growth factor in vivo
CONCLUSIONS: In vivo silencing of VEGF can affect cell survival and inhibit cell migration, invasion, and development, probably by enhancing apoptosis and inhibiting the expressions of MMP2 and MMP9.PMID:38708333 | PMC:PMC11063079 | DOI:10.2478/abm-2024-0009 (Source: Biomed Res)
Source: Biomed Res - May 6, 2024 Category: Research Authors: Shenglin Lu Jun Li Source Type: research
Bacteriophage-cocktail hydrogel dressing to prevent multiple bacterial infections and heal diabetic ulcers in mice
In this study we investigated whether the presence of phage itself could help repair delayed-healing wounds in diabetic mice. Three strains of phage that target Salmonella enterica, Escherichia coli, and Pseudomonas aeruginosa were used. To prevent the phage liquid from running off the wound, the mixture of phage (phage-cocktail) was encapsulated in a porous hydrogel dressing made with three-dimensional printing. The phage-cocktail dressing was tested for its phage preservation and release efficacy, bacterial reduction, cytotoxicity with 3T3 fibroblast, and performance in repairing a sterile full-thickness skin wound in di...
Source: Biomed Res - May 6, 2024 Category: Research Authors: Sheng-Jie Shiue Ming-Shun Wu Yi-Hsien Chiang Hsin-Yi Lin Source Type: research
Assessing computational predictions of antimicrobial resistance phenotypes from microbial genomes
Brief Bioinform. 2024 Mar 27;25(3):bbae206. doi: 10.1093/bib/bbae206.ABSTRACTThe advent of rapid whole-genome sequencing has created new opportunities for computational prediction of antimicrobial resistance (AMR) phenotypes from genomic data. Both rule-based and machine learning (ML) approaches have been explored for this task, but systematic benchmarking is still needed. Here, we evaluated four state-of-the-art ML methods (Kover, PhenotypeSeeker, Seq2Geno2Pheno and Aytan-Aktug), an ML baseline and the rule-based ResFinder by training and testing each of them across 78 species-antibiotic datasets, using a rigorous benchma...
Source: Briefings in Bioinformatics - May 6, 2024 Category: Bioinformatics Authors: Kaixin Hu Fernando Meyer Zhi-Luo Deng Ehsaneddin Asgari Tzu-Hao Kuo Philipp C M ünch Alice C McHardy Source Type: research
Treatment of cholangiocarcinoma by pGCsiRNA-vascular endothelial growth factor in vivo
CONCLUSIONS: In vivo silencing of VEGF can affect cell survival and inhibit cell migration, invasion, and development, probably by enhancing apoptosis and inhibiting the expressions of MMP2 and MMP9.PMID:38708333 | PMC:PMC11063079 | DOI:10.2478/abm-2024-0009 (Source: Cell Research)
Source: Cell Research - May 6, 2024 Category: Cytology Authors: Shenglin Lu Jun Li Source Type: research
Treatment of cholangiocarcinoma by pGCsiRNA-vascular endothelial growth factor in vivo
CONCLUSIONS: In vivo silencing of VEGF can affect cell survival and inhibit cell migration, invasion, and development, probably by enhancing apoptosis and inhibiting the expressions of MMP2 and MMP9.PMID:38708333 | PMC:PMC11063079 | DOI:10.2478/abm-2024-0009 (Source: Biomed Res)
Source: Biomed Res - May 6, 2024 Category: Research Authors: Shenglin Lu Jun Li Source Type: research
Bacteriophage-cocktail hydrogel dressing to prevent multiple bacterial infections and heal diabetic ulcers in mice
In this study we investigated whether the presence of phage itself could help repair delayed-healing wounds in diabetic mice. Three strains of phage that target Salmonella enterica, Escherichia coli, and Pseudomonas aeruginosa were used. To prevent the phage liquid from running off the wound, the mixture of phage (phage-cocktail) was encapsulated in a porous hydrogel dressing made with three-dimensional printing. The phage-cocktail dressing was tested for its phage preservation and release efficacy, bacterial reduction, cytotoxicity with 3T3 fibroblast, and performance in repairing a sterile full-thickness skin wound in di...
Source: Biomed Res - May 6, 2024 Category: Research Authors: Sheng-Jie Shiue Ming-Shun Wu Yi-Hsien Chiang Hsin-Yi Lin Source Type: research
Expression of Concern: Cell-Associated Flagella Enhance the Protection Conferred by Mucosally-Administered Attenuated < i > Salmonella < /i > Paratyphi A Vaccines
by The PLOS Neglected Tropical Diseases Editors (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - May 6, 2024 Category: Tropical Medicine Authors: The PLOS Neglected Tropical Diseases Editors Source Type: research
Prevalence, associated factors and antimicrobial susceptibility patterns of Salmonella and Shigella species among diarrheic under five children in Sultan Sheik Hassan Yabere referral Hospital, Jigjiga, Eastern Ethiopia
Diarrhea caused by Salmonella and Shigella species are the leading cause of illness especially in developing countries. These infections are considered as the main public health problems in children, including Et... (Source: BMC Pediatrics)
Source: BMC Pediatrics - May 6, 2024 Category: Pediatrics Authors: Kader Muse, Kedir Urgessa, Tadesse Shume, Bawlah Tahir and Fitsum Weldegebreal Tags: Research Source Type: research
Genetic recombination-mediated evolutionary interactions between phages of potential industrial importance and prophages of their hosts within or across the domains of Escherichia, Listeria, Salmonella, Campylobacter, and Staphylococcus
The in-depth understanding of the role of lateral genetic transfer (LGT) in phage-prophage interactions is essential to rationalizing phage applications for human and animal therapy, as well as for food and en... (Source: BMC Microbiology)
Source: BMC Microbiology - May 4, 2024 Category: Microbiology Authors: Saba Kobakhidze, Stylianos Koulouris, Nata Kakabadze and Mamuka Kotetishvili Tags: Research Source Type: research
Raw meat-based diet for pets: a neglected source of human exposure to < em > Salmonella < /em > and pathogenic < em > Escherichia coli < /em > clones carrying < em > mcr < /em > , Portugal, September 2019 to January 2020
ConclusionSome RMBDs from European brands available in Portugal can be a vehicle for clinically relevant MDR Salmonella and pathogenic E. coli clones carrying genes encoding resistance to the last-line antibiotic colistin. Proactive actions within the One Health context, spanning regulatory, pet-food industry and consumer levels, are needed to mitigate these public health risks.PMID:38699902 | DOI:10.2807/1560-7917.ES.2024.29.18.2300561 (Source: Euro Surveill)
Source: Euro Surveill - May 3, 2024 Category: Infectious Diseases Authors: Marisa Ribeiro-Almeida Joana Mour ão Mafalda Magalh ães Ana R Freitas Carla Novais Lu ísa Peixe Patr ícia Antunes Source Type: research
Prevalence and antimicrobial resistance of major foodborne pathogens isolated from pangas and tilapia fish sold in retail markets of Dhaka city, Bangladesh
The objective of this study was to evaluate the microbiological quality of tilapia and pangas fish sold in retail markets across Dhaka city, Bangladesh. Specifically, the study aimed to compare the quality of fish from traditional wet markets and modern supermarkets, as well as fish samples collected during morning and evening hours. A total of 500 raw cut-fish samples (250 tilapia and 250 pangas) were collected at the point of sale from 32 wet markets and 25 supermarkets. All samples were tested for Escherichia coli, extended-spectrum β-lactamase-producing E. coli (ESBL-Ec), along with the foodborne pathogens Salmonella,...
Source: International Journal of Food Microbiology - May 3, 2024 Category: Food Science Authors: Mohammed Badrul Amin Prabhat Kumar Talukdar Ajrin Sultana Sraboni Md Rayhanul Islam Zahid Hayat Mahmud David Berendes Clare Narrod Salina Parveen Mohammad Aminul Islam Source Type: research
Raw meat-based diet for pets: a neglected source of human exposure to < em > Salmonella < /em > and pathogenic < em > Escherichia coli < /em > clones carrying < em > mcr < /em > , Portugal, September 2019 to January 2020
ConclusionSome RMBDs from European brands available in Portugal can be a vehicle for clinically relevant MDR Salmonella and pathogenic E. coli clones carrying genes encoding resistance to the last-line antibiotic colistin. Proactive actions within the One Health context, spanning regulatory, pet-food industry and consumer levels, are needed to mitigate these public health risks.PMID:38699902 | DOI:10.2807/1560-7917.ES.2024.29.18.2300561 (Source: Euro Surveill)
Source: Euro Surveill - May 3, 2024 Category: Infectious Diseases Authors: Marisa Ribeiro-Almeida Joana Mour ão Mafalda Magalh ães Ana R Freitas Carla Novais Lu ísa Peixe Patr ícia Antunes Source Type: research
