Answer to Case 715
Answer to theParasite Case of the Week 715: Cockroach ootheca (egg case or ' purse ' )These fascinating structures contain about 30-40 eggs each. The female cockroach carries her ootheca until the eggs hatch and the first instar nymphs emerge. For those of you who had never heard of this phenomenon before, you can read moreHERE. In this case, we can see the emerging nymphs:Laura noted that the ootheca was hard and solid when it first arrived in the lab so she added some saline and waited for 30 minutes. This is when the nymphs began to poke out and she was able to remove them for individual viewing. Thinking abo...
Source: Creepy Dreadful Wonderful Parasites - April 23, 2023 Category: Parasitology Source Type: blogs
Typhoid Detection Technique Improves Diagnostic Sensitivity
A team at the University of California Davis Health working with international collaborators have developed a new technique to detect typhoid and estimate its incidence in populations over time. The approach requires only a drop of blood from a finger prick and involves measuring levels of antibodies against two antigens: Hemolysin E (Hlye) and Salmonella lipopolysaccharide (LPS). The researchers simplified the assay so that it can be performed in remote and low-resource regions. The method also employs AI to calculate antibody decay, which provides an indication of when someone was originally infected. This lets the resea...
Source: Medgadget - July 12, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Diagnostics Medicine Pathology Public Health typhoid UCDavis UCDavisHealth Source Type: blogs
Fight Aging! Newsletter, December 27th 2021
We report that whereas microglia are characterized by marked gene-level alterations related to negative regulation of protein phosphorylation and phagocytic vesicles, astrocytes show activation of enzyme- or peptidase-inhibitor signaling after detectable changes in BBB permeability. We also identify several genes enriched in these pathways that are notably altered after BBB breakdown. Our data reveal that microglia and astrocytes play an active role in maintaining BBB stabilization and corralling infiltrating cells, and thus might potentially function in ameliorating the lesions and neurologic disabilities in CNS diseases....
Source: Fight Aging! - December 26, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Nicotinamide Mononucleotide Supplement Adjusts the Gut Microbiome
In today's open access paper, the authors report on their investigation of the effects of nicotinamide mononucleotide (NMN) supplementation on the gut microbiome in mice. The gut microbiome changes with age, exhibiting a loss of helpful populations that produce metabolites necessary to health, and the growth in harmful populations that provoke chronic inflammation. Rejuvenating the aged gut microbiome via fecal microbiota transplantation from a young individual has been shown to improve health and extend life in short-lived species. Thus there is some interest in evaluating the effects on the gut microbiome produced by int...
Source: Fight Aging! - December 24, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Marijuana Microbe Test in Massachusetts Is Unnecessary and Counterproductive
Jeffrey Miron andRevana SharfuddinStates with legal marijuana typically require lab testing for specific pathogens, such as salmonella and aspergillus. But Massachusetts sets a low limit on the total amount of bacteria and fungus in each regulated unit of marijuana, regardless of whether that fungus or bacteria is harmful.The Boston Globereports:The standards are intended to protect consumers from moldy or bacteria ‐contaminated flower. But farmers across Massachusetts have complained that the state’s unusually tight rules are based on flimsy science, discourage outdoor growing and other sustainable practices, ...
Source: Cato-at-liberty - March 2, 2021 Category: American Health Authors: Jeffrey Miron, Revana Sharfuddin Source Type: blogs
All you need to know about waterborne diseases
Waterborne diseases are contracted through exposure to contaminated water including drinking water, water used in food preparation, and swimming water.
They can be caused by bacteria, viruses, and parasites. Below is a partial list of waterborne disease pathogens, their microbial classification, and their resulting illnesses.
Classification
Microorganism
Disease
Bacterium
Campylobacter spp.
Campylobacteriosis
Bacterium
Escherichia coli
E. Coli Diarrhea
Bacterium
Legionella pneumophila
Legionnaires’ Disease
Bacterium
Salmonella enterica
Salmonellosis
Bacterium
Salmonella typhi
Typhoid fever
...
Source: GIDEON blog - January 14, 2021 Category: Databases & Libraries Authors: Kristina Symes Tags: Microbiology News Tips Source Type: blogs
Typhoid Trump: A Public Health Threat
by Stephen P. Wood, MS,ACNP
Mary Mallon, better known as Typhoid Mary, was an asymptomatic carrier of Salmonella typhi, the organism known to cause typhoid fever. Mallon worked as a cook for eight different families in and around New York city, infecting seven of the families she worked for. There were a number of deaths in these families as typhoid had a 10% mortality rate at the time. George Soper, a sanitary engineer enlisted by one of the families affected, is credited with discovering Mallon as the source of this outbreak and he followed her around, collecting samples of her urine and ...
Source: blog.bioethics.net - October 5, 2020 Category: Medical Ethics Authors: Blog Editor Tags: Featured Posts Public Health #covid19 #Journalofaplagueyear COVID-19 medical history Typhoid Mary Source Type: blogs
Fight Aging! Newsletter, May 4th 2020
The objective is to start treating chronic diseases from the root and not the symptoms of the disease. As we are starting to enroll patients in "senolytics-clinical trials," it will be imperative to assess if senolysis efficiently targets the primary cause of disease or if it works best in combination with other drugs. Additional basic science research is required to address the fundamental role of senescent cells, especially in the established contexts of disease.
Notes on Self-Experimentation with Sex Steroid Ablation for Regrowth of the Thymus
https://www.fightaging.org/archives/2020/04/notes-on-self-experi...
Source: Fight Aging! - May 3, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
How to Plan and Carry Out a Simple Self-Experiment, a Single Person Trial of Flagellin Immunization
This lengthy post covers the topic of setting up and running a self-experiment, a human trial of a single individual, to assess whether a ten week course of flagellin immunization will significantly and beneficially affect gut microbe populations. Flagellin is the protein making up a flagellum, the appendage that bacteria use to move themselves around. As it happens, the presence of flagellae correlates decently well with harmful gut microbes, and the absence of flagellae correlates decently well with helpful gut microbes. In principle, provoking the immune system into greater efforts to chase down and destroy anything wit...
Source: Fight Aging! - April 27, 2020 Category: Research Authors: Reason Tags: Self-Experimentation Source Type: blogs
Outbreak of Salmonella Poisoning from Contaminated Vegetables in Massachusetts But DPH Refuses to Release Data on Which Products are Involved and Where They Were Purchased
Despite an outbreak of vegetable-associated Salmonella poisoning linked to products sold at Massachusetts restaurants that has affected 90 Massachusetts residents and resulted in three deaths, the Massachusetts Department of Public Health is refusing to release any information on the restaurants at which the patients ate or the exact products they consumed. The Department has revealed only that the outbreak is associated with " vegetable products " and that some of the patients reported having eaten vegetables at restaurants in the Commonwealth.The Department of Public Health is not even telling the restaurant owners thems...
Source: The Rest of the Story: Tobacco News Analysis and Commentary - December 9, 2019 Category: Addiction Source Type: blogs
Tennessee Department of Health Appears to Have Deliberately Blamed E-Cigarettes for a Death It Knew Was Caused by THC Carts
Yesterday, I revealed that the Tennessee Department of Healthreported its first death from vaping-associated respiratory illness as follows: "The Tennessee Department of Health has reported one death in a patient with serious respiratory disease associated with use of electronic cigarettes or other vaping devices. This is the first such death reported in Tennessee. "As it turns out, it appears that this death was not caused by electronic cigarettes, but byTHC vape carts.I suggested that the health department ' s reporting of the death as being associated with the use of " electronic cigarettes or other vaping devices " wou...
Source: The Rest of the Story: Tobacco News Analysis and Commentary - October 18, 2019 Category: Addiction Source Type: blogs
Tennessee Department of Health Tragically Misleads the Public in Order to Falsely Blame a Death on E-Cigarettes
Sadly, Tennessee recently experienced itsfirst death from vaping-associated respiratory illness.Here ' s how the Tennessee Department of Healthreported it:" The Tennessee Department of Health has reported one death in a patient with serious respiratory disease associated with use of electronic cigarettes or other vaping devices. This is the first such death reported in Tennessee. "So which one was it? Was it the use of " electronic cigarettes " or was it the use of " other vaping devices. " If the Tennessee Department of Health truly wants to prevent further cases of this illness, it is incumbent upon the agency to inform ...
Source: The Rest of the Story: Tobacco News Analysis and Commentary - October 18, 2019 Category: Addiction Source Type: blogs
The CDC is Still Misleading the Public about the Cause of the Respiratory Disease Outbreak: Why?
Last Thursday, CDC finally revised itswarning to the public about the vaping-associated respiratory disease outbreak to state clearly that vaping THC-containing products is playing a major role in the outbreak. It stated that:" The latest national and state findings suggest products containing THC, particularly those obtained off the street or from other informal sources (e.g. friends, family members, illicit dealers), are linked to most of the cases and play a major role in the outbreak. Therefore, CDC recommends that you should not use e-cigarette, or vaping, products that contain THC."In addition, CDC finallyrecommended...
Source: The Rest of the Story: Tobacco News Analysis and Commentary - October 14, 2019 Category: Addiction Source Type: blogs
Despite Increasing Clarity in Role of Illicit THC Vape Carts in Lung Injury Outbreak, CDC Violating Its Own Principles to Blame E-Cigarettes
The role of illicit THC vape carts in the lung injury outbreak --which has now caused 7 deaths--continues to become clear. Yesterday, Dallas County reported14 new cases ranging in age from 16 to 44 with a median age of 19, all of whom were hospitalized with severe respiratory distress. Although the news headline mentions only that these cases were associated with " vaping, " if you read down to the 11th paragraph, you find out that" Ninety percent of the Dallas County cases reported vaping THC products. "The CDC has continually downplayed the role of THC vape carts in the outbreak and even today, continues to blame it on e...
Source: The Rest of the Story: Tobacco News Analysis and Commentary - September 17, 2019 Category: Addiction Source Type: blogs
Fight Aging! Newsletter, August 19th 2019
In conclusion, our data show how oncogenic and tumor-suppressive drivers of cellular senescence act to regulate surveillance processes that can be circumvented to enable SnCs to elude immune recognition but can be reversed by cell surface-targeted interventions to purge the SnCs that persist in vitro and in patients. Since eliminating SnCs can prevent tumor progression, delay the onset of degenerative diseases, and restore fitness; since NKG2D-Ls are not widely expressed in healthy human tissues and NKG2D-L shedding is an evasion mechanism also employed by tumor cells; and since increasing numbers of B cells express NKG2D ...
Source: Fight Aging! - August 18, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
