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Total 37833 results found since Jan 2013.
mpMRI-targeted biopsy of the prostate in men ≥ 75 years. 7-year report from a high-volume referral center
CONCLUSION: After evaluation of a large patient cohort, we show that age≥75 years represents a significant risk factor for the detection of clinically significant prostate cancer. Further studies on mid- and long term outcome are necessary to draw conclusions for clinical decision making in this patient cohort.PMID:37718788 | DOI:10.3233/CH-238101
Source: Clinical Hemorheology and Microcirculation - September 18, 2023 Category: Hematology Authors: Michael Chaloupka Nikolaos Pyrgidis Benedikt Ebner Paulo Pfitzinger Yannic Volz Elena Berg Benazir Abrarova Michael Atzler Troya Ivanova Paulo Pfitzinger Christian G Stief Maria Apfelbeck Dirk-Andr é Clevert Source Type: research
Baseline prostate health index risk category and risk category changes during active surveillance predict grade reclassification
CONCLUSIONS: Baseline PHI risk category and PHI changes over time were both independent predictors of GR after confirmatory biopsy, but the added benefit over PSAD seemed modest. However, baseline PHI and PHI risk category changes provided clinically useful risk stratification for time to GR, so further evaluation of PHI's ability to help reduce the frequency of mpMRI and/or surveillance biopsies with more PHI data points over time may be warranted.PMID:37722985 | DOI:10.1016/j.urolonc.2023.08.011
Source: Urologic Oncology - September 18, 2023 Category: Urology & Nephrology Authors: Claire M de la Calle Yuezhou Jing Mufaddal M Mamawala Patricia Landis Katarzyna J Macura Bruce J Trock Jonathan I Epstein Lori J Sokoll Christian P Pavlovich Source Type: research
The Value of < sup > 18 < /sup > F-FDG PET/MRI in Detecting Lumbar Radiculopathy for Selective Percutaneous Endoscopic Discectomy: a Case Report
Nucl Med Mol Imaging. 2023 Oct;57(5):247-250. doi: 10.1007/s13139-023-00797-3. Epub 2023 Mar 29.ABSTRACTMagnetic resonance imaging (MRI) is the most popular imaging modality for investigating intervertebral disc herniation. However, it has a high chance for identifying incidental findings that are morphologically or structurally abnormal but not responsible for patients' symptoms. Although a previous study suggested that 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/magnetic resonance imaging (PET/MRI) may help identify neuroinflammation in lumbar radiculopathy, there is currently no direct evidence obtaine...
Source: Molecular Medicine - September 18, 2023 Category: Molecular Biology Authors: Chih-Ying Su Guo-Shu Huang Wei-Chou Chang Chih-Chien Wang Chun-Wen Chen Yi-Chih Hsu Source Type: research
Stimuli-Responsive Codelivery System Self-Assembled from < em > in Situ < /em > Dynamic Covalent Reaction of Macrocyclic Disulfides for Cancer Magnetic Resonance Imaging and Chemotherapy
ACS Appl Mater Interfaces. 2023 Sep 18. doi: 10.1021/acsami.3c10245. Online ahead of print.ABSTRACTSupramolecular self-assembly has gained increasing attention to construct multicomponent drug delivery systems for cancer diagnosis and therapy. Despite that these self-assembled nanosystems present surprising properties beyond that of each subcomponent, the spontaneous nature of co-self-assembly causes significant difficulties in control of the synthesis process and consequently leads to unsatisfactory influences in downstream applications. Hence, we utlized an in situ dynamic covalent reaction based on thiol-disulfide excha...
Source: Cancer Control - September 18, 2023 Category: Cancer & Oncology Authors: Xiaoxia Wu Dinghu Zhang Ting Pan Jianwei Li Yujiao Xie Chenguang Zhang Chunshu Pan Zhewei Zhang Jie Lin Aiguo Wu Guoliang Shao Source Type: research
Diseases of the Coronary Microcirculation: Diagnosis and Treatment
CONCLUSION: Approximately 25% of patients with CMD have symptoms that do not respond to intensive treatment with the currently available modalities. New treatments, including interventional therapies, are being studied. Their long-term benefit remains to be assessed and compared to that of the existing methods.PMID:37721132 | DOI:10.3238/arztebl.m2023.0205
Source: Deutsches Arzteblatt International - September 18, 2023 Category: General Medicine Authors: Helen Ullrich-Daub Steffen Daub Maximilian Olschewski Thomas M ünzel Tommaso Gori Source Type: research
Radiation-dependent demyelination in normal appearing white matter in glioma patients, determined using quantitative magnetic resonance imaging
CONCLUSION: In the long-term follow-up for glioma patients, qMRI is a powerful tool for detecting small changes, such as a decrease of myelin concentration, in NAWM after CRT.PMID:37720464 | PMC:PMC10500023 | DOI:10.1016/j.phro.2023.100451
Source: Health Physics - September 18, 2023 Category: Physics Authors: Anna Ljusberg Ida Blystad Peter Lundberg Emelie Adolfsson Anders Tisell Source Type: research
Cone beam computed tomography image guidance within a magnetic resonance imaging-only planning workflow
CONCLUSION: The results of this study support the concept that with focussed training, an MRI to CBCT image guidance approach can be successfully implemented in a clinical planning workflow.PMID:37720461 | PMC:PMC10500022 | DOI:10.1016/j.phro.2023.100472
Source: Health Physics - September 18, 2023 Category: Physics Authors: Laura M O'Connor Alesha Quinn Samuel Denley Lucy Leigh Jarad Martin Jason A Dowling Kate Skehan Helen Warren-Forward Peter B Greer Source Type: research
Infant body composition: A comprehensive overview of assessment techniques, nutrition factors, and health outcomes
Nutr Clin Pract. 2023 Oct;38 Suppl 2:S7-S27. doi: 10.1002/ncp.11059.ABSTRACTBody composition assessment is a valuable tool for clinical assessment and research that has implications for long-term health. Unlike traditional measurements such as anthropometrics or body mass index, body composition assessments provide more accurate measures of body fatness and lean mass. Moreover, depending on the technique, they can offer insight into regional body composition, bone mineral density, and brown adipose tissue. Various methods of body composition assessment exist, including air displacement plethysmography, dual-energy x-ray ab...
Source: Nutrition in Clinical Practice - September 18, 2023 Category: Nutrition Authors: Maggie L Jerome Vivian Valcarce Laura Lach Elena Itriago Ariel A Salas Source Type: research
Relationship between seminal vesicle displacement and distribution of hydrogel spacer within the perirectal space in prostate radiotherapy
In conclusion, SV cranial displacement was influenced by HS lateral distribution of ≥1.00 cm in the upper two slices. Therefore, when the sigmoid colon or small bowel is depressed in rectovesical excavation and SV needs to be included in the target volume, HS insertion should be performed carefully.PMID:37719041 | PMC:PMC10502802 | DOI:10.3892/mco.2023.2674
Source: Clinical Prostate Cancer - September 18, 2023 Category: Cancer & Oncology Authors: Kenji Makita Yasushi Hamamoto Hiromitsu Kanzaki Kei Nagasaki Katsuyoshi Hashine Source Type: research
mpMRI-targeted biopsy of the prostate in men ≥ 75 years. 7-year report from a high-volume referral center
CONCLUSION: After evaluation of a large patient cohort, we show that age≥75 years represents a significant risk factor for the detection of clinically significant prostate cancer. Further studies on mid- and long term outcome are necessary to draw conclusions for clinical decision making in this patient cohort.PMID:37718788 | DOI:10.3233/CH-238101
Source: Clinical Prostate Cancer - September 18, 2023 Category: Cancer & Oncology Authors: Michael Chaloupka Nikolaos Pyrgidis Benedikt Ebner Paulo Pfitzinger Yannic Volz Elena Berg Benazir Abrarova Michael Atzler Troya Ivanova Paulo Pfitzinger Christian G Stief Maria Apfelbeck Dirk-Andr é Clevert Source Type: research
Bone marrow edema at ligament insertion is an accurate MRI sign of deltoid ligament injury
CONCLUSION: BMELI can reliably indicate concomitant injury to the DL in CAI patients. Using BMELI as a sign of chronic DL injury when ALMC is unclear may reduce the risk of a false negative diagnosis.PMID:37722764 | DOI:10.1177/02841851231197508
Source: Acta Radiologica - September 18, 2023 Category: Radiology Authors: Jiahui Tong Hong Li Hongyun Li Yinghui Hua Source Type: research
Assessment of brainstem function and haemodynamics by MRI: challenges and clinical prospects
Br J Radiol. 2023 Sep 18:20220940. doi: 10.1259/bjr.20220940. Online ahead of print.ABSTRACTMRI offers techniques for non-invasively measuring a range of aspects of brain tissue function. Blood oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI) is widely used to assess neural activity, based on the brain's haemodynamic response, while arterial spin labelling (ASL) MRI is a non-invasive method of quantitatively mapping cerebral perfusion. Both techniques can be applied to measure cerebrovascular reactivity (CVR), an important marker of the health of the cerebrovascular system. BOLD, ASL and CVR ...
Source: The British Journal of Radiology - September 18, 2023 Category: Radiology Authors: Owen Bleddyn Woodward Ian Driver Stefan Theodor Schwarz Emma Hart Richard Wise Source Type: research
Artificial intelligence in breast imaging: potentials and challenges
Phys Med Biol. 2023 Sep 18. doi: 10.1088/1361-6560/acfade. Online ahead of print.ABSTRACTBreast cancer, which is the most common type of malignant tumor among humans, is a leading cause of death in females. Standard treatment strategies, including neoadjuvant chemotherapy, surgery, postoperative chemotherapy, targeted therapy, endocrine therapy, and radiotherapy, are tailored for individual patients. Such personalized therapies have tremendously reduced the threat of breast cancer in females. Furthermore, early imaging screening plays an important role in reducing the treatment cycle and improving breast cancer prognosis. ...
Source: Physics in Medicine and Biology - September 18, 2023 Category: Physics Authors: Jiawei Li Danli Sheng Jiangang Chen Chao You Shuai Liu Huixiong Xu Cai Chang Source Type: research
Distinct serum GDNF coupling with brain structural and functional changes underlies cognitive status in Parkinson's disease
CONCLUSION: Our findings reveal that the topological features of brain networks and cortical thickness are altered in PD patients with cognitive deficits. The above change, accompanied by the serum GDNF, may have merit as a diagnosis marker for PD and, arguably, cognition status.PMID:37718594 | DOI:10.1111/cns.14461
Source: CNS Neuroscience and Therapeutics - September 18, 2023 Category: Neuroscience Authors: Chuanxi Tang Ruiao Sun Ke Xue Mengying Wang Sijie Liang Piniel Alphayo Kambey Mingyu Shi Changyu Wu Gang Chen Dianshuai Gao Source Type: research
Disentangling accelerated cognitive decline from the normal aging process and unraveling its genetic components: A neuroimaging-based deep learning approach
Conclusion Our deep learning model was demonstrated effective on extracting relevant neuroimaging features and predicting individual cognitive decline. We reported a novel variant (rs144614292) within the NELL1 gene. Our approach has the potential to disentangle accelerated cognitive decline from the normal aging process and to determine its related genetic factors, leveraging opportunities for early intervention.PMID:37720047 | PMC:PMC10503860 | DOI:10.21203/rs.3.rs-3328861/v1
Source: Cell Research - September 18, 2023 Category: Cytology Authors: Yulin Dai Yu-Chun Hsu Brisa S Fernandes Kai Zhang Xiaoyang Li Nitesh Enduru Andi Liu Astrid M Manuel Xiaoqian Jiang Zhongming Zhao Source Type: research
