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Total 256 results found since Jan 2013.

SMART (stroke-like migraine attack after radiation therapy) syndrome: a case report with review of the literature
Source: Neurological Sciences - October 14, 2015 Category: Neurology Source Type: research

Stroke-like migraine attacks after radiation therapy (SMART) Syndrome causing permanent neurological deficit
Dalveer Singh, Charlie Chia-Tsong HsuAnnals of Indian Academy of Neurology 2016 19(1):129-130
Source: Annals of Indian Academy of Neurology - February 2, 2016 Category: Neurology Authors: Dalveer SinghCharlie Chia-Tsong Hsu Source Type: research

Effects of local irradiation combined with sunitinib on early remodeling, mitochondria, and oxidative stress in the rat heart.
CONCLUSIONS: This study found no early enhanced effects of radiation and sunitinib on cardiac function or structure. Long-term effects remain to be determined. PMID: 27072940 [PubMed - as supplied by publisher]
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 8, 2016 Category: Radiology Authors: Sridharan V, Thomas CJ, Cao M, Melnyk SB, Pavliv O, Joseph J, Singh SP, Sharma S, Moros EG, Boerma M Tags: Radiother Oncol Source Type: research

Cerebral Hyperperfusion in a Child with Stroke-Like Migraine Attacks after Radiation Therapy Syndrome
We report an 11-year-old girl with a primary diagnosis of medulloblastoma presented with acute-onset severe headache and left-sided weakness, 20 months after completing cranial radiotherapy. MRI demonstrated unilateral cortical swelling and concomitant leptomeningeal, gyral contrast enhancement, and MR perfusion imaging showed increased cortical perfusion in the right temporo-parieto-occipital region. Her symptoms resolved spontaneously over several days.SMART syndrome appears to be a reversible, long-term complication of cranial radiotherapy. So far, a limited number of pediatric patients with SMART syndrome have been rep...
Source: Neuropediatrics - April 21, 2016 Category: Neurology Authors: Ardicli, DidemGocmen, RahsanOguz, Kader K.Varan, AliYalnizoglu, Dilek Tags: Short Communication Source Type: research

Surgical salvage of recurrent vestibular schwannoma following prior stereotactic radiosurgery
ConclusionMicrosurgical salvage of VS following primary radiation therapy is challenging. Less‐than‐complete resection is required in a greater percentage of patients to preserve facial nerve integrity and prevent neurological complications. Long‐term follow‐up is needed to determine the risk of delayed progression following incomplete tumor removal. Level of EvidenceLevel 3. Laryngoscope, 2016
Source: The Laryngoscope - April 22, 2016 Category: ENT & OMF Authors: Stephanie C. Wise, Matthew L. Carlson, Øystein Vesterli Tveiten, Colin L. Driscoll, Erling Myrseth, Morten Lund‐Johansen, Michael J. Link Tags: Otology/Neurotology Source Type: research

Treatment of pediatric cerebral radiation necrosis: a systematic review
Abstract Cerebral radiation necrosis (CRN) is a toxicity of radiation therapy that can result in significant, potentially life-threatening neurologic deficits. Treatment for CRN has included surgical resection, corticosteroids, hyperbaric oxygen therapy (HBOT), and bevacizumab, but no consensus approach has been identified. We reviewed the available literature to evaluate efficacy of treatment approaches. Using methods specified in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines when possible, we conducted searches of Ovid MEDLINE, Embase and Pubmed to identify studies re...
Source: Journal of Neuro-Oncology - July 19, 2016 Category: Cancer & Oncology Source Type: research

E-067 Endovascular Approach in the Repair of the Middle Cerebral Artery Aneurysm Including Those with Wide Neck and Complex in Morphology-A Case Series
ConclusionsEndovascular repair of the MCA aneurysm inclosing those with wide neck and complex are not only safe and feasible, but associated with high long-term functional outcome. Therefore, endovascular options must be offered to patients prior to surgical clipping of a MCA aneurysm. Further study may be warranted.DisclosuresY. Lodi: None. V. Reddy: None.
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Lodi, Y., Reddy, V. Tags: Electronic poster abstracts Source Type: research

SMART syndrome: Classic transient symptoms leading to an unusual unfavorable outcome.
CONCLUSION: SMART syndrome may progress from a benign reversible form to a severe and eventually irreversible form. This severe course may also be confused with tumor progression, and lead to permanent disability and inadequate antitumor treatment. Clinicians should be aware of this latter atypical presentation. PMID: 27919464 [PubMed - as supplied by publisher]
Source: Revue Neurologique - December 8, 2016 Category: Neurology Tags: Rev Neurol (Paris) Source Type: research

Updates in outcomes of stereotactic radiation therapy in acromegaly
Conclusion Although the use of radiotherapy in patients with acromegaly has decreased with advances in medical treatments, it remains an effective treatment option after unsuccessful surgery and/or resistance or unavailability of medical therapy. Long-term studies evaluating secondary morbidity and mortality rate after the new stereotactic techniques are needed, in order to evaluate their potential brain-sparing effect.
Source: Pituitary - February 15, 2017 Category: Endocrinology Source Type: research

A 15-year-old girl with acute and reversible neurologic symptoms after cranial irradiation for medulloblastoma
A 15-year-old girl with history of medulloblastoma was evaluated for headache and acute onset neurologic deficits 5 years after completion of initial radiation therapy and 3 years following completion of re-irradiation. Neurological examination was notable for new onset left hemianopia, hemiparesis and neglect. MRI showed extensive areas of cortical T2 prolongation and thickening involving the right parietal, occipital and temporal lobes, with associated extensive gyral enhancement. Upon spontaneous resolution of her weakness after 4 days, repeat MRI showed resolution of the edema and gyral enhancement, suggestive of the d...
Source: Seminars in Pediatric Neurology - April 1, 2017 Category: Neurology Authors: Elizabeth Duke, Nicole J Ullrich Source Type: research

A 15-Year-Old Girl With Sudden Onsent Reversible Neurologic Symptoms After Cranial Irradiation for Medulloblastoma
A 15-year-old girl with history of medulloblastoma was evaluated for headache and neurologic deficits 5 years after completion of initial radiation therapy and 3 years following completion of reirradiation. Neurologic examination was notable for new-onset left hemianopia, hemiparesis, and neglect. Magnetic resonance imaging showed extensive areas of cortical T2 prolongation and thickening involving the right parietal, occipital, and temporal lobes with associated extensive gyral enhancement. Upon spontaneous resolution of her weakness after 4 days, repeat magnetic resonance imaging showed resolution of the edema and gyral ...
Source: Seminars in Pediatric Neurology - April 1, 2017 Category: Neurology Authors: Elizabeth Duke, Nicole J. Ullrich Source Type: research

Reversible hemispheric hypoperfusion in two cases of SMART syndrome
We present two cases demonstrating reversible hemispheric hypoperfusion. Case 1 presented with left hemispheric symptoms following previous similar episodes. CT perfusion (CTP) demonstrated reversible hemispheric hypoperfusion; subsequent investigations were consistent with SMART syndrome. Case 2 presented following the third episode of a hemispheric syndrome with near-identical CTP abnormalities. L-arginine was administered with rapid reversal of clinical and CTP abnormalities. We conclude that SMART syndrome may demonstrate significant hypoperfusion on hyperacute CTP without subsequent infarction. Impaired cerebrovascula...
Source: Journal of Clinical Neuroscience - June 21, 2017 Category: Neuroscience Source Type: research

SMART syndrome with cerebral angiographic abnormalities - A case report
Black et al. first used the terminology ‘stroke-like migraine attacks after radiation therapy (SMART) syndrome’ and proposed diagnostic criteria in 2006 [1]. Proposed diagnostic criteria are remote history of cerebral radiotherapy, prolonged but reversible signs and symptoms referable to a unilateral cortical region and nearly reversi ble diffuse gyral and leptomeningeal enhancement within the symptomatic area [2]. However, these criteria do not include angiographic features. To the best of our knowledge, our case is the first report to show vascular change by means of digital subtraction angiography.
Source: Journal of the Neurological Sciences - August 22, 2017 Category: Neurology Authors: Ji-Hyung Park, Moo-seok Park, Gyeong-Moon Kim Tags: Letter to the Editor Source Type: research

Efficacy and safety in frameless robot-assisted stereo-electroencephalography (SEEG) for drug-resistant epilepsy.
CONCLUSION: Frameless robot-assisted SEEG appears to be a safe procedure, providing sufficient accuracy in order to delineate the epileptogenic zone and represents a helpful tool in the pre-surgical management of refractory epilepsy. PMID: 28882607 [PubMed - as supplied by publisher]
Source: Neuro-Chirurgie - September 4, 2017 Category: Neurosurgery Authors: Ollivier I, Behr C, Cebula H, Timofeev A, Benmekhbi M, Valenti MP, Staack AM, Scholly J, Kehrli P, Hirsch E, Proust F Tags: Neurochirurgie Source Type: research

Mortality following benign sacral insufficiency fracture and associated risk factors
ConclusionsLike other types of osteoporotic fractures, sacral insufficiency fractures are associated with increased mortality.
Source: Archives of Orthopaedic and Trauma Surgery - November 9, 2017 Category: Orthopaedics Source Type: research