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Specialty: Transplant Surgery

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Total 557 results found since Jan 2013.

Depletion of circ_0006459 protects human brain microvascular endothelial cells from oxygen-glucose deprivation-induced damage through the miR-940/FOXJ2 pathway
CONCLUSION: Depletion of circ_0006459 protected human brain microvascular endothelial cells from oxygen-glucose deprivation-induced damage through miR-940/FOXJ2 pathway, providing a promising therapeutic target for ischemic stroke.PMID:36608833 | DOI:10.1016/j.trim.2022.101780
Source: Transplant Immunology - January 7, 2023 Category: Transplant Surgery Authors: Wei Li Hong Pang Lin Xie Source Type: research

Central extracorporeal membrane oxygenation with left-ventricular vent for fulminant myocarditis: a retrospective study
ConclusionsCentral ECMO with an LV vent was effective for fulminant myocarditis refractory to percutaneous cardiopulmonary support therapy and other therapies.
Source: Journal of Artificial Organs - November 8, 2022 Category: Transplant Surgery Source Type: research

Impact of time off anticoagulation in patients with continuous-flow left ventricular assist devices
AbstractPatients with left ventricular assist devices (LVADs) receive anticoagulation to decrease the risk of thrombosis. Various circumstances require discontinuing anticoagulation in LVAD patients, but the risks entailed are not well defined. In a retrospective review of LVAD implantation procedures, we examined the effect of time off anticoagulation on thrombosis and mortality rates after implantation. An international normalized ratio  ≤ 1.5 was used to screen for patients taken off anticoagulation. Patients were divided into three groups by the cumulative number of days off anticoagulation: no discontinuation, s...
Source: Journal of Artificial Organs - October 8, 2022 Category: Transplant Surgery Source Type: research

Right heart failure after left ventricular assist device implantation – from prediction to action
In this issue of the Journal, Read and colleagues1 report the use of peak stroke volume index (SVI) during pre-procedure vasodilatory testing as a predictor of early right heart failure (RHF) after left ventricular assist device (LVAD) implantation. They retrospectively examine 70 patients from three institutions who underwent pre-implant nitroprusside vasodilator testing. Indications for pre-operative vasodilator testing were elevated pulmonary vascular resistance, pulmonary arterial wedge pressure, or systolic pulmonary artery pressure.
Source: The Journal of Heart and Lung Transplantation - August 31, 2022 Category: Transplant Surgery Authors: Sameer K Singh, Koji Takeda Tags: Editorial Source Type: research

Expanded Criteria Donors
Exp Clin Transplant. 2022 Aug;20(Suppl 4):13-19. doi: 10.6002/ect.DonorSymp.2022.L13.ABSTRACTThe expanded criteria donor is any donor over the age of 60 years or a donor over the age of 50 years with 2 of the following 3 items: (1) history of high blood pressure, (2) serum creatinine ≥1.5 mg/dL, and (3) death due to stroke. To accept an expanded criteria donor kidney may significantly decrease the amount of time a person waits for transplant but requires written informed consent from the recipient. Although expanded criteria donor kidneys have predictably shorter outcomes than standard criteria donors, the exact risk is ...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - August 26, 2022 Category: Transplant Surgery Authors: Hassan Argani Source Type: research

Three-year experience of catheter-based micro-axial left ventricular assist device, Impella, in Japanese patients: the first interim analysis of Japan registry for percutaneous ventricular assist device (J-PVAD)
AbstractCatheter-based micro-axial ventricular assist device Impella ® (Abiomed, Danvers, MA) has been used in Japanese patients with drug-refractory acute heart failure (AHF) since 2017. This is the first interim analysis of the ongoing Japan Registry for Percutaneous Ventricular Assist Device (J-PVAD) to investigate the safety and efficacy of Impella support. Betw een October 2017 and January 2020, 823 Japanese patients, who were treated with the Impella 2.5, CP, or 5.0 pump, were enrolled. The primary endpoints were safety profiles and cumulative 30-day survival. Among them, 44.8% of patients were acute myocardial infa...
Source: Journal of Artificial Organs - April 25, 2022 Category: Transplant Surgery Source Type: research

Three-Year Experience of Kidney Transplantation at a Single Center in Uzbekistan
CONCLUSIONS: Delayed graft function developed when duration of warm ischemia was increased, which was influenced by the number of vessels in the donor kidney. This is an important prognostic factor for acute rejection development. The risk of vascular complications increases due to postoperative hemodialysis trough, with development of delayed graft function. Recipient deaths during the first year after kidney transplant were mainly from pulmonary embolism, infection, and sepsis as a result of immunosuppression, hypovolemic shock, and acute ischemic stroke.PMID:35384804 | DOI:10.6002/ect.MESOT2021.O10
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - April 6, 2022 Category: Transplant Surgery Authors: Abdukhakim Khadjibaev Farhod Khadjibaev Rano Rakhimova Visolat Sharipova Pulat Sultanov Dilshod Ergashev Khikmat Anvarov Malika Ruzibakieva Source Type: research