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Specialty: Transplant Surgery

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Total 557 results found since Jan 2013.

Impact of mechanical circulatory support on post-transplant stroke risk
This study assesses if the type of circulatory support device affects stroke risk in this population. The study cohort of 4257 adult patients bridged with mechanical support to cardiac transplant were derived from the UNOS transplant registry data. Risk factors assessed were age, gender, ischemic time, diabetes (recipient), durable mechanical support at listing and mechanical ventilation pre-transplant. Descriptive statistics were used to describe characteristics of the study cohort. Univariate logistic regression was used to test if there is a significant association between stroke event and all the potential risk factors...
Source: The International Journal of Artificial Organs - August 19, 2021 Category: Transplant Surgery Authors: Nandini Nair Shengping Yang Enrique Gongora Source Type: research

Concomitant Mitochondrial Diabetes and Myopathy Mistook for Complications of Immunosuppressants After Kidney Transplant
We report the case of a 48-year-old woman with diabetes mellitus, sensorineural hearing loss, and severe myopathy without neuropathy after deceased donor kidney transplant. ShehadamitochondrialDNApointmutation at position 3243 (A>G), and mitochondrial diseases such as maternally inherited diabetes deafness or mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodeswere suspected.Diabetes andother symptoms following kidney transplant can often be overlooked as complications of immunosuppressants taken after kidney transplant. However, in patients without a known cause of their symptoms, appropriate exam...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - July 30, 2021 Category: Transplant Surgery Authors: Yong Hoon Shin Ae Jin Kim Han Ro Jae Hyun Chang Ji Yong Jung Woo Kyung Chung Hyun Hee Lee Source Type: research

Major Thromboembolic Complications in Liver Transplantation: The Role of Rotational Thromboelastometry and Cryoprecipitate Transfusion
Background. Although hemorrhage is a major concern during liver transplantation (LT), the risk for thromboembolism is well recognized. Implementation of rotational thromboelastometry (ROTEM) has been associated with the increased use of cryoprecipitate; however, the role of ROTEM-guided transfusion strategy and cryoprecipitate administration in the development of major thromboembolic complications (MTCs) has never been documented. Methods. We conducted a study on patients undergoing LT before and after the implementation of ROTEM. We defined MTC as intracardiac thrombus, pulmonary embolism, hepatic artery thromb...
Source: Transplantation - July 28, 2021 Category: Transplant Surgery Tags: Original Clinical Science—Liver Source Type: research

Outcomes of systemic anticoagulation with bivalirudin for Impella 5.0
Int J Artif Organs. 2021 Jul 12:3913988211032238. doi: 10.1177/03913988211032238. Online ahead of print.ABSTRACTTemporary mechanical circulatory support (tMCS) devices are used for the management of cardiogenic shock. The Impella 5.0 (Abiomed; Danvers, MA) (IMP5) is a commonly used, surgically implanted, tMCS device that requires systemic anticoagulation and purge solution to avoid pump failure. To avoid heparin-induced thrombocytopenia (HIT) from unfractionated heparin (UFH) use, our program has explored the utility of bivalirudin (BIV) for systemic anticoagulation in IMP5. This single center, retrospective study included...
Source: The International Journal of Artificial Organs - July 12, 2021 Category: Transplant Surgery Authors: Carly Fabrizio Marissa N Levito Ryan Rivosecchi Michael Bashline Brittany Slocum Arman Kilic Catalin Toma Holt Murray Raj Ramanan Jeffrey Fowler Gavin W Hickey Edward T Horn Source Type: research

Plethysmography Variability Index and Stroke Volume Variation Changes in Relation to Central Venous Pressure Changes During Living Related Donor Right Hepatotomy: A Diagnostic Test Accuracy
CONCLUSIONS: Plethysmography variability index and stroke volume variation showed negligible correlation and poor agreement with central venous pressure. Transfusion-free dissection was possible despite normovolemia, with median values of 8 mm Hg central venous pressure, 10% stroke volume variation, and 12% plethysmography variability index. Plethysmography variability index and stroke volume variation were unable to discriminate donors with increased blood loss.PMID:34085912 | DOI:10.6002/ect.2021.0546
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - June 4, 2021 Category: Transplant Surgery Authors: Yasmin Abdelsalam Kamel Amany Said Ammar Omnai Gamal Baiomy Mamdouh El-Sayed Lotfi Khaled Ahmed Yassen Source Type: research