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Total 32 results found since Jan 2013.

Gut Microbiota-Derived Short-Chain Fatty Acids Promote Post-Stroke Recovery in Aged Mice.
Conclusions:This is the first study suggesting that the poor stroke recovery in aged mice can be reversed via "post-stroke bacteriotherapy" following the replenishment of youthful gut microbiome via modulation of immunologic, microbial and metabolomic profiles in the host. PMID: 32354259 [PubMed - as supplied by publisher]
Source: Circulation Research - April 30, 2020 Category: Cardiology Authors: Lee J, d'Aigle J, Atadja L, Quaicoe V, Honarpisheh P, Ganesh BP, Hassan A, Graf J, Petrosino JF, Putluri N, Zhu L, Durgan DJ, Bryan RM, McCullough LD, Venna VR Tags: Circ Res Source Type: research

Organizing stroke systems in the field for patients with suspected large vessel occlusion acute stroke.
Authors: Almekhlafi MA, Holodinsky JK, Hill MD, Kamal N, Goyal M Abstract INTRODUCTION: The dawn of endovascular stroke therapy has reshaped stroke care. Eligible patients need to be rushed to capable centers for intervention. This may entail bypassing closer hospitals that could confirm the diagnosis, administer thrombolytic therapy, then transfer patients for intervention. This has created a set of challenges: identifying endovascular candidates in the field, determining the best transport destination, and getting patients there quickly. Areas covered: This review provides a context for these emerging challenges....
Source: Expert Review of Cardiovascular Therapy - November 20, 2018 Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research

Ethics and Bias in Clinical Trial Enrollment in Stroke
AbstractPurpose of ReviewTo familiarize the reader with ethical concerns and potential scientific bias in management and conduction of clinical stroke trials.Recent FindingsThe goal of clinical trials in stroke is to find effective interventions for stroke prevention, acute treatment, and rehabilitation and recovery. Acute trials must be designed in the context of the time-sensitivity of revascularization therapies. Standard ethical constraints apply. However, informed consent is hindered by tight time windows for reperfusion therapy and frequent cognitive impairment in patients. These might be mitigated by using visual de...
Source: Current Cardiology Reports - April 21, 2019 Category: Cardiology Source Type: research

Assessing the characteristics and diagnostic value of plaques for patients with acute stroke using high-resolution magnetic resonance imaging
CONCLUSIONS: A larger plaque area and smaller LA in the stenotic MCA, and obvious plaque enhancement might indicate that a patient is prone to acute stroke.PMID:35111645 | PMC:PMC8739121 | DOI:10.21037/qims-21-531
Source: Atherosclerosis - February 3, 2022 Category: Cardiology Authors: Danfeng Zhang Mi Wang Lili Wu Ying Zhao Siyu Wang Xindao Yin Xinying Wu Source Type: research

Availability of patient decision aids for stroke prevention in atrial fibrillation: A systematic review
The objective of this review was to examine the existence and accessibility of, as well as select outcomes associated with, published, formally evaluated patient decision aids for stroke prevention in atrial fibrillation. Methods Six databases were searched from inception to March 2016 with a research librarian. Two authors independently reviewed potential articles, selected trials meeting inclusion criteria, and assessed outcome measures. Outcomes included: patient knowledge, involvement, choice, and decisional conflict. Results The search resulted in 666 articles; most were excluded for not examining stroke prevention in...
Source: American Heart Journal - June 3, 2017 Category: Cardiology Source Type: research

Abstract 272: Preliminary Data from RESOLVE (Rapid Evaluation for Stroke Outcomes using Lytics in Vascular Events) Study Session Title: Poster Session II
Conclusions: Preliminary findings showed that less than half of the patients and CG felt the education was clear. However additional interviews are planned. Preliminary insights suggest an opportunity to use an individualized risk and benefit decision tool to inform and engage patients and CG regarding treatment decisions. We believe this can be accomplished without increasing the door to needle time in administration of rt-PA.
Source: Circulation: Cardiovascular Quality and Outcomes - June 2, 2014 Category: Cardiology Authors: Summers, D., Chhatriwalla, E., Gialde, E., Spertus, J., Decker, C. Tags: Session Title: Poster Session II Source Type: research

Brain Stimulation Aids Post-Stroke Arm Recovery
SAN DIEGO (MedPage Today) -- Magnetic brain stimulation added to hand and arm rehabilitation after a stroke nearly doubled the improvement in motor control, a pilot study showed.
Source: MedPage Today Cardiovascular - February 17, 2014 Category: Cardiology Source Type: news

Exercise Aids in Stroke Recovery
Title: Exercise Aids in Stroke RecoveryCategory: Health NewsCreated: 5/20/2014 4:36:00 PMLast Editorial Review: 5/21/2014 12:00:00 AM
Source: MedicineNet Heart General - May 21, 2014 Category: Cardiology Source Type: news

Minute Stroke Distance is a More Reproducible Measurement Than Cardiac Output in the Assessment of Fetal Ventricular Systolic Function
Echocardiographic quantification of fetal cardiac output (CO) aids clinical decision-making in the management of various cardiac and extracardiac diseases. Small variability in measuring semilunar valve dimension significantly reduces the reproducibility of the calculated CO. We propose minute stroke distance or velocity-time integral (VTI) as a more reproducible measure reflecting fetal ventricular systolic function. We hypothesized that right and left ventricular minute VTI increase predictably with estimated fetal weight (EFW) and are more reproducible than CO.
Source: Journal of the American Society of Echocardiography - August 13, 2022 Category: Cardiology Authors: Heather Y. Sun, Elif Seda Selamet Tierney, Theresa A. Tacy, Rajesh Punn Tags: Clinical Investigations Source Type: research

A risk assessment tool incorporating new biomarkers for cardiovascular events in acute coronary syndromes: the Organization to Assess Strategies in Ischemic Syndromes (OASIS) risk score
Conclusions The addition of NT-proBNP and hemoglobin A1C to 5 standard variables creates a 7-variable risk score that improves prediction of cardiovascular events at 1 year and aids in risk-based selection of NSTEACS patients for dual antiplatelet therapy. Teaser Several new biomarkers improve risk stratification in non-ST-segment elevation ACS, however they are not integrated into risk prediction tools. A risk score to predict CV death/MI/stroke was developed by incorporating new biomarkers with standard variables. The addition of NT-proBNP and hemoglobin A1C to 5 standard variables (age, prior MI/stroke, sex, ST-segment ...
Source: Canadian Journal of Cardiology - February 3, 2016 Category: Cardiology Source Type: research

Genotype-phenotype associations in atrial fibrillation: meta-analysis
ConclusionsPooled analysis showed a significantly high prevalence of stroke (10%) inRS2200733 AF patients. AF patients with the studied SNPs had preserved left ventricular systolic function (i.e., ejection fraction greater than 50%). AF patients withRS10033464 presented larger left atrium diameter (44  mm (95% CI 42.02–45.98)) than those with other SNPs. The late AF recurrence rate was highest inRS2200733 patients (53% (95% CI 0.43 –0.64)). This study aids our understanding of the existing genetic findings and the function-altering “strongest” SNPs.
Source: Journal of Interventional Cardiac Electrophysiology - November 17, 2018 Category: Cardiology Source Type: research

Score Aids Treatment Decision in Mild Large-Vessel Stroke Score Aids Treatment Decision in Mild Large-Vessel Stroke
Location and length of thrombus can identify those at highest risk for early neurologic deterioration, flagging those who may be the best candidates for thrombectomy.Medscape Medical News
Source: Medscape Cardiology Headlines - January 15, 2021 Category: Cardiology Tags: Neurology & Neurosurgery News Source Type: news

Vessel wall magnetic resonance imaging of symptomatic middle cerebral artery atherosclerosis: A systematic review and meta-analysis
CONCLUSION: Based on current evidence, contrast enhancement and T1 hyperintensity on high-resolution MRI have high potential as imaging biomarkers of patients with MCA plaques at risk of ischemic events. Future prospective, longitudinal studies of intracranial-plaque high-resolution MRI are required to improve decision-making for the management of intracranial atherosclerotic plaques.PMID:35952437 | DOI:10.1016/j.clinimag.2022.08.001
Source: Atherosclerosis - August 11, 2022 Category: Cardiology Authors: Rongwei Yang Jiang Yuan Xiuen Chen Xufeng Xie Ziming Ye Chao Qin Source Type: research

Predictors of Long-Term Outcomes in Patients with Significant Myxomatous Mitral Regurgitation Undergoing Exercise Echocardiography.
CONCLUSIONS: In patients with ≥III+ myxomatous MR undergoing ExEc, lower %age-gender predicted METS, lower HRR, atrial fibrillation, lower LV ejection fraction and high resting RVSP predicted worse outcomes. PMID: 24396041 [PubMed - as supplied by publisher]
Source: Circulation - January 6, 2014 Category: Cardiology Authors: Naji P, Griffin BP, Asfahan F, Barr TS, Rodriguez LL, Grimm R, Agarwal S, Stewart WJ, Mihaljevic T, Gillinov AM, Desai MY Tags: Circulation Source Type: research

Importance of Exercise Capacity in Predicting Outcomes and Determining Optimal Timing of Surgery in Significant Primary Mitral Regurgitation Valvular Heart Disease
Conclusion In patients with primary MR that underwent exercise echocardiography followed by MV surgery, lower achieved metabolic equivalents were associated with worse long-term outcomes. In those with preserved exercise capacity, delaying MV surgery by ≥1 year did not adversely affect outcomes.
Source: JAHA:Journal of the American Heart Association - September 11, 2014 Category: Cardiology Authors: Naji, P., Griffin, B. P., Barr, T., Asfahan, F., Gillinov, A. M., Grimm, R. A., Rodriguez, L. L., Mihaljevic, T., Stewart, W. J., Desai, M. Y. Tags: Valvular Heart Disease Source Type: research