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Glowing Proteins Enable Stem Cell Stimulation for Stroke Recovery in Mice
A new method helps neural stem cells form synaptic connections, thereby restoring lost brain function.
Source: The Scientist - October 1, 2019 Category: Science Tags: The Literature Magazine Issue Source Type: news
Structural basis for power stroke vs. Brownian ratchet mechanisms of motor proteins Biophysics and Computational Biology
Two mechanisms have been proposed for the function of motor proteins: The power stroke and the Brownian ratchet. The former refers to generation of a large downhill free energy gradient over which the motor protein moves nearly irreversibly in making a step, whereas the latter refers to biasing or rectifying...
Source: Proceedings of the National Academy of Sciences - September 30, 2019 Category: Science Authors: Wonmuk Hwang, Martin Karplus Tags: Perspective Source Type: research
Man sees world in miniature after having a stroke
Publication date: 28 September 2019Source: New Scientist, Volume 243, Issue 3249Author(s): Alice Klein
Source: New Scientist - September 27, 2019 Category: Science Source Type: research
In vitro antioxidant, 𝛼-amylase and 𝛼-glucosidase activities of methanol extracts from three Momordica species
AbstractAntioxidant based drug preparations are used in the prevention and management of complex diseases which include atherosclerosis, stroke, diabetes, alzheimer ’s disease and cancer. Diabetes mellitus is a metabolic disorder of glucose metabolism. The management of blood glucose level is the hallmark in the treatment of this ailment, which may be achieved through the use of oral hypoglycemic drugs such as biguanides, insulin secretagogues, and 𝛼-amyla se and glucosidase inhibitors. Although several biological activities had been reported for MomordicafoetidaandMomordicacharantia; it appears there is limited info...
Source: International Journal of Phytomedicine - August 25, 2019 Category: Science Authors: Olubunmi Adenike Akinwunmi Source Type: research
In vitro antioxidant, α-amylase and α-glucosidase activities of methanol extracts from three Momordica species
AbstractAntioxidant based drug preparations are used in the prevention and management of complex diseases which include atherosclerosis, stroke, diabetes, alzheimer ’s disease and cancer. Diabetes mellitus is a metabolic disorder of glucose metabolism. The management of blood glucose level is the hallmark in the treatment of this ailment, which may be achieved through the use of oral hypoglycemic drugs such as biguanides, insulin secretagogues, and 𝛼-amyla se and glucosidase inhibitors. Although several biological activities had been reported for MomordicafoetidaandMomordicacharantia; it appears there is limited info...
Source: International Journal of Phytomedicine - August 25, 2019 Category: Science Authors: Oubunmi Adenike Akinwunmi Source Type: research
Heart attacks and the efficacy of polypills – a hard pill to swallow? | Letters
Dr Peter Trewby questions the risk-reduction figures of the Iran study andOliver Lepen says the focus must be on preventing disease, not medicationYour headline (Single polypill reduces risk of heart attacks and strokes, study finds, 23 August) should really have been tempered by quoting the absolute rather than the relative risk-reduction figures.The 34% reduction in major cardiac events you quote is calculated from “on the ground” reduction in events from 8.8% over five years in those not on the polypill to 5.9% in those receiving it – that is a 2.9% chance of benefit over five years to the individual and with no e...
Source: Guardian Unlimited Science - August 25, 2019 Category: Science Authors: Letters Tags: Drugs Health Society Science Heart disease Heart attack Stroke Medical research Medicine Pharmaceuticals industry Source Type: news
Single polypill reduces risk of heart attacks and strokes, study finds
Large trial held in Iran of inexpensive medication combining four common drugsA cheap, single pill taken once a day that combines four common drugs is safe and reduces the risk of events such as heart attacks, strokes and sudden death in people over the age of 50, research has found.The study, the first large-scale trial to date, looked at the effectiveness of a so-called polypill – a four-in-one therapy containing drugs to lower cholesterol and blood pressure that was first proposed more than 15 years ago. The researchers found those taking the polypill had a more than 30% lower risk of serious heart problems than those...
Source: Guardian Unlimited Science - August 23, 2019 Category: Science Authors: Nicola Davis Tags: Medical research Heart disease Heart attack Stroke Health Pharmaceuticals industry Drugs Science Iran Source Type: news
Kids' Brains Remarkably Plastic After Stroke
A small study reports that, among children who had left-hemisphere damage as newborns, the complementary region of the right hemisphere appears to compensate and protect language development.
Source: The Scientist - August 23, 2019 Category: Science Tags: News & Opinion Source Type: news
Insomniacs may be at greater risk of heart failure, study finds
People genetically predisposed to sleep problems have greater risk of stroke and coronary artery diseasePeople who struggle with sleep might be at greater risk of developing cardiovascular problems, research suggests.Scientists have found that people who are genetically predisposed to insomnia have a greater risk of heart failure, stroke and coronary artery disease.Continue reading...
Source: Guardian Unlimited Science - August 19, 2019 Category: Science Authors: Nicola Davis Tags: Sleep Health & wellbeing Life and style Science Heart disease Stroke UK news Society Source Type: news
Cardiovascular disease risk greater in people prone to insomnia - study
People genetically predisposed to sleep problems have greater risk of heart failure and stroke, say researchersPeople who struggle with sleep might be at greater risk of developing cardiovascular problems, research suggests.Scientists have found that people who are genetically predisposed to insomnia have a greater risk of heart failure, stroke and coronary artery disease.Continue reading...
Source: Guardian Unlimited Science - August 19, 2019 Category: Science Authors: Nicola Davis Tags: Sleep Health & wellbeing Life and style Science Heart disease Stroke UK news Society Source Type: news
Scientists Predict Climate Change Will Make Dangerous Heat Waves Far More Common
People all across the U.S. have been sweating through heat waves this summer, and new research suggests they should get used to it.
Over the next century, climate change will likely make extreme heat conditions—and their concordant health risks—much more frequent in nearly every part of the U.S., according to a paper published in the journal Environmental Research Communications. By the end of the century, it says, parts of the Gulf Coast states could experience more than 120 days per year that feel like they top 100°F.
The study was conducted by researchers from the Union of Concerned Scientists (UCS), a n...
Source: TIME: Science - July 16, 2019 Category: Science Authors: Jamie Ducharme Tags: Uncategorized Research Source Type: news
Shape memory nanocomposite fibers for untethered high-energy microengines
Classic rotating engines are powerful and broadly used but are of complex design and difficult to miniaturize. It has long remained challenging to make large-stroke, high-speed, high-energy microengines that are simple and robust. We show that torsionally stiffened shape memory nanocomposite fibers can be transformed upon insertion of twist to store and provide fast and high-energy rotations. The twisted shape memory nanocomposite fibers combine high torque with large angles of rotation, delivering a gravimetric work capacity that is 60 times higher than that of natural skeletal muscles. The temperature that triggers fiber...
Source: ScienceNOW - July 10, 2019 Category: Science Authors: Yuan, J., Neri, W., Zakri, C., Merzeau, P., Kratz, K., Lendlein, A., Poulin, P. Tags: Materials Science reports Source Type: news
Device could bring both solar power and clean water to millions
Researchers say one invention could solve two problems for people lacking basic resourcesA device that can produce electricity from sunlight while simultaneously purifying water has been produced by researchers, an invention they say could solve two problems in one stroke.The researchers say the device is not only a source of green energy but also offers an alternative to current technologies for purifying water. These, they add, often consume large amounts of electricity and require infrastructure beyond the reach of many communities that lack basic access to safe drinking water – a situation thought to affect more than...
Source: Guardian Unlimited Science - July 10, 2019 Category: Science Authors: Nicola Davis Tags: Science Water Global health Solar power Renewable energy Environment World news Source Type: news
Nogo-A targeted therapy promotes vascular repair and functional recovery following stroke Neuroscience
Stroke is a major cause of serious disability due to the brain’s limited capacity to regenerate damaged tissue and neuronal circuits. After ischemic injury, a multiphasic degenerative and inflammatory response is coupled with severely restricted vascular and neuronal repair, resulting in permanent functional deficits. Although clinical evidence indicates that revascularization...
Source: Proceedings of the National Academy of Sciences - July 8, 2019 Category: Science Authors: Ruslan Rust, Lisa Gronnert, Christina Gantner, Alinda Enzler, Geertȷe Mulders, Rebecca Z. Weber, Arthur Siewert, Yanuar D. P. Limasale, Andrea Meinhardt, Michael A. Maurer, Andrea M. Sartori, Anna–Sophie Hofer, Carsten Werner, Martin E. Schwa Tags: PNAS Plus Source Type: research
Region-specific and activity-dependent regulation of SVZ neurogenesis and recovery after stroke Neuroscience
Stroke is the leading cause of adult disability. Neurogenesis after stroke is associated with repair; however, the mechanisms regulating poststroke neurogenesis and its functional effect remain unclear. Here, we investigate multiple mechanistic routes of induced neurogenesis in the poststroke brain, using both a forelimb overuse manipulation that models a clinical...
Source: Proceedings of the National Academy of Sciences - July 1, 2019 Category: Science Authors: Huixuan Liang, Handi Zhao, Amy Gleichman, Michal Machnicki, Sagar Telang, Sydney Tang, Mary Rshtouni, Jack Ruddell, S. Thomas Carmichael Tags: PNAS Plus Source Type: research
