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Total 1260 results found since Jan 2013.
Stroke epidemiology in southern Brazil: Investigating the relationship between stroke severity, hospitalization costs, and health-related quality of life
An Acad Bras Cienc. 2022 Jun 13;94(2):e20211492. doi: 10.1590/0001-3765202220211492. eCollection 2022.ABSTRACTWe aimed with the present study to fill the gap on the performance and safety of stroke management and the costs related to hospitalizations, the relevant comorbidities associated with stroke patients, and the stroke patient outcomes health-related quality of life (HRQOL) progress. Our study investigated the clinical, neurological, and social impact of stroke in 220 patients in a tertiary hospital located in the countryside of the state of Santa Catarina, Brazil. Description of clinical and neurological characteris...
Source: An Acad Bras Cienc - June 15, 2022 Category: Science Authors: Denise M Tereza Gabriela M Baldasso Rodrigo S Paes Antonio R DE S á Junior Marui W C Giehl Rafael C Dutra Source Type: research
Taboo stops south Asian people in UK seeking help for dementia, says charity
Exclusive: Alzheimer ’s Society says fear of embarrassment or misunderstanding stops thousands coming forwardThousands of south Asian people living with dementia in the UK are being denied access to help and support because stigma and taboo deter them from getting diagnosed, a charity has warned.People from south Asian communities are more likely to develop dementia than the general UK population due to being at higher risk of other illnesses, such as heart disease, stroke and diabetes, that increase the risk of dementia.Continue reading...
Source: Guardian Unlimited Science - May 15, 2022 Category: Science Authors: Andrew Gregory Health editor Tags: Alzheimer's Dementia Health Society UK news Science Source Type: news
Certain gut microbes may affect stroke risk and severity, scientists find
Studies of ischaemic stroke patients open up possibility of treatments to prevent condition and improve recoveryScientists have identified specific groups of gut microbes that could increase or decrease someone ’s risk of suffering the most common type of stroke. The research, presented at the European Stroke Organisation Conference (ESOC) in Lyon, France, adds to growing evidence that alterations in the gut microbiome could play a role in cardiovascular disease.Previous studies have suggested that certain microbes may influence the formation of atherosclerotic plaques in the arteries, and that the gut microbiomes of str...
Source: Guardian Unlimited Science - May 4, 2022 Category: Science Authors: Linda Geddes Science correspondent Tags: Stroke Biology Science Microbiology Health Medical research Source Type: news
New blood test predicts risk of heart attack and stroke with twice previous accuracy
New technique, already available in US, could aid in development of cardiovascular drugsScientists have developed a blood test that can predict whether someone is at high risk of a heart attack, stroke, heart failure or dying from one of these conditions within the next four years.The test, which relies of measurements of proteins in the blood, has roughly twice the accuracy of existing risk scores. It could enable doctors to determine whether patients ’ existing medications are working or whether they need additional drugs to reduce their risk.Continue reading...
Source: Guardian Unlimited Science - April 6, 2022 Category: Science Authors: Linda Geddes Tags: Heart attack Stroke Health Medical research Science World news Society Source Type: news
Long-term paracetamol use may be a risk for people with high blood pressure
Use of drug could raise risk of heart disease and stroke over time, study of 110 people suggestsLong-term paracetamol use could increase the risk of heart disease and strokes in people with high blood pressure, a study suggests.Patients who have a long-term prescription for the painkiller, usually used for the treatment of chronic pain, should opt for the lowest effective dose for the shortest possible time, researchers say.Continue reading...
Source: Guardian Unlimited Science - February 8, 2022 Category: Science Authors: Andrew Gregory Health editor Tags: Drugs Heart disease Stroke Health Science Source Type: news
The NEDD8-activating enzyme inhibitor MLN4924 reduces ischemic brain injury in mice Neuroscience
Blood–brain barrier (BBB) breakdown and inflammation occurring at the BBB have a key, mainly a deleterious role in the pathophysiology of ischemic stroke. Neddylation is a ubiquitylation-like pathway that is critical in various cellular functions by conjugating neuronal precursor cell-expressed developmentally down-regulated protein 8 (NEDD8) to target proteins. However, the...
Source: Proceedings of the National Academy of Sciences - January 31, 2022 Category: Science Authors: Huilin Yu, Haiyu Luo, Luping Chang, Shisheng Wang, Xue Geng, Lijing Kang, Yi Zhong, Yongliang Cao, Ranran Wang, Xing Yang, Yuanbo Zhu, Mei-Juan Shi, Yue Hu, Zhongwang Liu, Xuhui Yin, Yunwei Ran, Hao Yang, Wenying Fan, Bing-Qiao Zhao Tags: Neuroscience Biological Sciences Source Type: research
Tea and coffee may be linked to lower risk of stroke and dementia – study
Research looking at 365,000 people aged 50-74 finds moderate consumption could have health benefitsDrinking coffee or tea may be linked with a lower risk of stroke and dementia, according to the largest study of its kind.Strokes cause 10% of deaths globally, while dementia is one of the world ’s biggest health challenges – 130 million are expected to be living with it by 2050.Continue reading...
Source: Guardian Unlimited Science - November 16, 2021 Category: Science Authors: Andrew Gregory Health editor Tags: Health Stroke Dementia Tea Coffee Medical research Science Food Alzheimer's Society Source Type: news
Agonistic analog of growth hormone-releasing hormone promotes neurofunctional recovery and neural regeneration in ischemic stroke Neuroscience
Ischemic stroke can induce neurogenesis. However, most stroke-generated newborn neurons cannot survive. It has been shown that MR-409, a potent synthetic agonistic analog of growth hormone–releasing hormone (GHRH), can protect against some life-threatening pathological conditions by promoting cell proliferation and survival. The present study shows that long-term treatment with MR-409...
Source: Proceedings of the National Academy of Sciences - November 15, 2021 Category: Science Authors: Yueyang Liu, Jingyu Yang, Xiaohang Che, Jianhua Huang, Xianyang Zhang, Xiaoxiao Fu, Jialing Cai, Yang Yao, Haotian Zhang, Ruiping Cai, Xiaomin Su, Qian Xu, Fu Ren, Renzhi Cai, Andrew V. Schally, Ming-Sheng Zhou Tags: Neuroscience Biological Sciences Source Type: research
Critical Period After Stroke Study (CPASS): A phase II clinical trial testing an optimal time for motor recovery after stroke in humans Neuroscience
Restoration of human brain function after injury is a signal challenge for translational neuroscience. Rodent stroke recovery studies identify an optimal or sensitive period for intensive motor training after stroke: near-full recovery is attained if task-specific motor training occurs during this sensitive window. We extended these findings to adult humans...
Source: Proceedings of the National Academy of Sciences - September 20, 2021 Category: Science Authors: Alexander W. Dromerick, Shashwati Geed, Jessica Barth, Kathaleen Brady, Margot L. Giannetti, Abigail Mitchell, Matthew A. Edwardson, Ming T. Tan, Yizhao Zhou, Elissa L. Newport, Dorothy F. Edwards Tags: Neuroscience Biological Sciences Source Type: research
Bioinformatic analysis for potential biological processes and key targets of heart failure-related stroke
This study aimed to uncover underlying mechanisms and promising intervention targets of heart failure (HF)-related stroke. HF-related dataset GSE42955 and stroke-related dataset GSE58294 were obtained from the Gene Expression Omnibus (GEO) database. Weighted gene co-expression network analysis (WGCNA) was conducted to identify key modules and hub genes. Gene Ontology (GO) and pathway enrichment analyses were performed on genes in the key modules. Genes in HF- and stroke-related key modules were intersected to obtain common genes for HF-related stroke, which were further intersected with hub genes of stroke-related key modu...
Source: J Zhejiang Univ Sci ... - September 13, 2021 Category: Science Authors: Chiyu Liu Sixu Chen Haifeng Zhang Yangxin Chen Qingyuan Gao Zhiteng Chen Zhaoyu Liu Jingfeng Wang Source Type: research
