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Total 1260 results found since Jan 2013.
Scorned scientist now vindicated in her work on how to treat stroke
Anne Abbott challenged medical establishment and faced ‘shocking’ rebuffsAnne Abbott is a scientist on a mission. She believes large numbers of debilitating strokes can be prevented without surgical interventions. Lifestyle changes and medication alone can make massive improvements to people at risk from the thickening of their arteries.It is not an attitude that has endeared her to the medical establishment, however. For years, it has attempted to block her work while instead pressing for increasing use of carotid surgery and stents, she told theObserver last week.Continue reading...
Source: Guardian Unlimited Science - December 19, 2020 Category: Science Authors: Robin McKie, Science Editor Tags: Stroke Science Medical research UK news Source Type: news
Mechanisms of collision recovery in flying beetles and flapping-wing robots
At rest, beetles fold and tuck their hindwings under the elytra. For flight, the hindwings are deployed through a series of unfolding configurations that are passively driven by flapping forces. The folds lock into place as the wing fully unfolds and thereafter operates as a flat membrane to generate the aerodynamic forces. We show that in the rhinoceros beetle (Allomyrina dichotoma), these origami-like folds serve a crucial shock-absorbing function during in-flight wing collisions. When the wing collides with an object, it collapses along the folds and springs back in place within a single stroke. Collisions are thus damp...
Source: ScienceNOW - December 3, 2020 Category: Science Authors: Phan, H. V., Park, H. C. Tags: Engineering, Physiology reports Source Type: news
Zoloft enters list of 10 most commonly prescribed drugs in Australia
Increase in women being diagnosed with depression partly behind rise in useAn increase in women being diagnosed with depression is partly behind a significant rise in prescriptions of the antidepressant sertraline – sold under the brand name Zoloft – which is in the list of Australia’s most commonly prescribed drugs for the first time.On Tuesday Australian Prescriberpublished its annual list of the 10 most commonly taken drugs – based on standard daily doses for every 1,000 people in the population each day – along with a list of the 10 most costly drugs to government, and the 10 most common drugs by prescription...
Source: Guardian Unlimited Science - November 30, 2020 Category: Science Authors: Melissa Davey Tags: Health Australia news Pharmaceuticals industry Depression Mental health Heart disease Stroke Psychology Drugs Women's health Source Type: news
Coupling of NMDA receptors and TRPM4 guides discovery of unconventional neuroprotectants
Excitotoxicity induced by NMDA receptors (NMDARs) is thought to be intimately linked to high intracellular calcium load. Unexpectedly, NMDAR-mediated toxicity can be eliminated without affecting NMDAR-induced calcium signals. Instead, excitotoxicity requires physical coupling of NMDARs to TRPM4. This interaction is mediated by intracellular domains located in the near-membrane portions of the receptors. Structure-based computational drug screening using the interaction interface of TRPM4 in complex with NMDARs identified small molecules that spare NMDAR-induced calcium signaling but disrupt the NMDAR/TRPM4 complex. These i...
Source: ScienceNOW - October 8, 2020 Category: Science Authors: Yan, J., Bengtson, C. P., Buchthal, B., Hagenston, A. M., Bading, H. Tags: Neuroscience, Online Only r-articles Source Type: news
Leslie Iversen obituary
Neuropharmacologist who searched for new gateways for drugs to treat the brain and mindAfflictions of the mind and brain, from stroke to schizophrenia, remain among the most challenging to treat, even after more than half a century of discoveries about the brain ’s biochemistry and how it responds to drugs. The neuropharmacologist Leslie Iversen, who has died aged 82, devoted his career to making sense of the interplay of signalling molecules in the nervous system that might provide sites where drugs could act.After directing laboratories in both the public sector and the pharmaceutical industry, in his later years Ivers...
Source: Guardian Unlimited Science - September 18, 2020 Category: Science Authors: Georgina Ferry Tags: Drugs Science People in science Drugs policy Medicine Source Type: news
Controlling for lesions, kinematics and physiological noise: impact on fMRI results of spastic post-stroke patients
Publication date: Available online 9 September 2020Source: MethodsXAuthor(s): Nabila Brihmat, Kader Boulanouar, Robert Darmana, Arnauld Biganzoli, David Gasq, Evelyne Castel-Lacanal, Philippe Marque, Isabelle Loubinoux
Source: MethodsX - September 10, 2020 Category: Science Source Type: research
High blood pressure and diabetes impair brain function, study suggests
The conditions appeared to cause structural changes that harmed memory and thinkingHigh blood pressure and diabetes bring about brain changes that impair thinking and memory, research suggests.Doctors examined brain scans and medical data from 22,000 volunteers enrolled in the UK Biobank project and found significant structural changes in the grey and white matter among those with diabetes and high blood pressure.Continue reading...
Source: Guardian Unlimited Science - September 7, 2020 Category: Science Authors: Ian Sample Science editor Tags: Health Heart attack Stroke Medical research Diabetes Science UK news World news Source Type: news
Prescribe blood pressure monitors to reduce stroke, UK charity says
Giving home monitors to those with high blood pressure would reduce heart attacks and other conditionsBlood pressure monitors should be handed out on prescription to slash the number of people who die or are left with disabilities from strokes and heart attacks, a medical charity has said.Making the home monitors available to anyone diagnosed with high blood pressure would allow people to control the condition more effectively and reduce the demand on GPs ’ surgeries,Blood Pressure UK said.Continue reading...
Source: Guardian Unlimited Science - September 6, 2020 Category: Science Authors: Ian Sample Science editor Tags: Health Stroke Heart attack Heart disease UK news Science Society Source Type: news
Blood Replacement Rescues Mice from Stroke Damage
When mice that had suffered a stroke were given blood from a healthy donor, they experienced less tissue and neurological damage.
Source: The Scientist - August 31, 2020 Category: Science Tags: News & Opinion Source Type: news
Artificial Intelligence Is Here To Calm Your Road Rage
I am behind the wheel of a Nissan Leaf, circling a parking lot, trying not to let the day’s nagging worries and checklists distract me to the point of imperiling pedestrians. Like all drivers, I am unwittingly communicating my stress to this vehicle in countless subtle ways: the strength of my grip on the steering wheel, the slight expansion of my back against the seat as I breathe, the things I mutter to myself as I pilot around cars and distracted pedestrians checking their phones in the parking lot.
“Hello, Corinne,” a calm voice says from the audio system. “What’s stressing you out right n...
Source: TIME: Science - August 26, 2020 Category: Science Authors: Corinne Purtill Tags: Uncategorized Source Type: news
Sheila Youngson obituary
My friend and colleague Sheila Youngson, who has died aged 65 from a stroke, was a clinical psychologist in the NHS from 1981, focusing on children and young people.Her final clinical post, from 1998 to 2010, was as consultant clinical psychologist at St James ’ hospital, in Leeds, where she was based at the paediatric renal unit. Within the medicalised environment of the hospital, she worked with persistence and sensitivity to introduce her child-centred approach to the emotional needs of the young patients.Continue reading...
Source: Guardian Unlimited Science - July 14, 2020 Category: Science Authors: Jude Boyles Tags: Psychology People in science Source Type: news
Warning of serious brain disorders in people with mild coronavirus symptoms
UK neurologists publish details of mildly affected or recovering Covid-19 patients with serious or potentially fatal brain conditionsCoronavirus – latest updatesSee all our coronavirus coverageDoctors may be missing signs of serious and potentially fatal brain disorders triggered by coronavirus, as they emerge in mildly affected or recovering patients, scientists have warned.Neurologists are on Wednesday publishing details of more than 40 UK Covid-19 patients whose complications ranged from brain inflammation and delirium to nerve damage and stroke. In some cases, the neurological problem was the patient ’s first and m...
Source: Guardian Unlimited Science - July 8, 2020 Category: Science Authors: Ian Sample Science editor Tags: Coronavirus outbreak Science Health Neuroscience UK news Infectious diseases Source Type: news
Clonally expanding smooth muscle cells promote atherosclerosis by escaping efferocytosis and activating the complement cascade Medical Sciences
Atherosclerosis is the process underlying heart attack and stroke. Despite decades of research, its pathogenesis remains unclear. Dogma suggests that atherosclerotic plaques expand primarily via the accumulation of cholesterol and inflammatory cells. However, recent evidence suggests that a substantial portion of the plaque may arise from a subset of “dedifferentiated”...
Source: Proceedings of the National Academy of Sciences - July 6, 2020 Category: Science Authors: Ying Wang, Vivek Nanda, Daniel Direnzo, Jianqin Ye, Sophia Xiao, Yoko Koȷima, Kathryn L. Howe, Kai–Uwe Jarr, Alyssa M. Flores, Pavlos Tsantilas, Noah Tsao, Abhiram Rao, Alexandra A. C. Newman, Anne V. Eberhard, James R. Priest, Arno Ruusalepp Tags: Biological Sciences Source Type: research
Severe Neurological Ailments Reported in COVID-19 Patients
A survey of hospitalized patients finds some suffer fatigue, ischemic stroke, delirium, and other symptoms.
Source: The Scientist - June 29, 2020 Category: Science Tags: News & Opinion Source Type: news
Covid-19 may cause brain complications in some, say doctors
Stroke and psychosis found in small study of patients highlight need for researchCoronavirus – latest updatesSee all our coronavirus coverageBrain complications, including stroke and psychosis, have been linked to Covid-19 in a study that raises concerns about the potentially extensive impact of the disease in some patients.The study is small and based on doctors ’ observations, so cannot provide a clear overall picture about the rate of such complications. However, medical experts say the findings highlight the need to investigate the possible effects of Covid-19 in the brain and studies to explore potential treatment...
Source: Guardian Unlimited Science - June 26, 2020 Category: Science Authors: Hannah Devlin Science correspondent Tags: Medical research Coronavirus outbreak Stroke Neuroscience UK news Health Source Type: news
